|
rs9939609
|
|
|
0.790 |
GeneticVariation |
BEFREE |
The rs9939609 polymorphism in the FTO gene has recently been implicated as a risk factor for some types of cancer, such as breast, pancreatic, and prostate cancers.
|
29260910 |
2018 |
|
rs9939609
|
|
|
0.790 |
GeneticVariation |
BEFREE |
The study objective was to assess the prevalence of cardiovascular disease risk factors in patients treated for childhood cancer (<i>N</i> = 101) and to determine the involvement of clinical (cancer type and therapy) and/or genetic (<i>FTO</i> gene rs9939609 polymorphism) factors.
|
29675043 |
2018 |
|
rs9939609
|
|
|
0.790 |
GeneticVariation |
BEFREE |
Besides, in the subgroup analysis of ethnicity, our results indicated that rs9939609 polymorphism was significantly associated with cancer risk in Asians.
|
26931363 |
2017 |
|
rs9939609
|
|
|
0.790 |
GeneticVariation |
BEFREE |
However, <i>FTO</i> rs9939609 variant was associated with some types of cancer in the subgroup analysis.
|
28881622 |
2017 |
|
rs9939609
|
|
|
0.790 |
GeneticVariation |
BEFREE |
Variants (such as rs9939609) in the fat mass- and obesity-associated (FTO) gene have been associated with obesity, type 2 diabetes, some cancers, and alcohol consumption.
|
23771786 |
2013 |
|
rs9939609
|
|
|
0.790 |
GeneticVariation |
BEFREE |
Our meta-analysis indicated that there was no association between FTO rs9939609 polymorphism and the increased risk of c</span>ancer, although this polymorphism was marginally associated with pancreatic cancer.
|
22396042 |
2012 |
|
rs9939609
|
|
|
0.790 |
GeneticVariation |
BEFREE |
Among 22,799 individuals (44-74 years) in the population-based Malmö diet and cancer cohort that were genotyped for rs9939609 in FTO and had information on dietary intake (from a modified diet history method) and no history of diabetes, cancer or cardiovascular disease, 2255 deaths (including 1100 cancer and 674 cardiovascular deaths) occurred during 12.0 years of follow-up.
|
21179003 |
2011 |
|
rs9939609
|
|
|
0.790 |
GeneticVariation |
BEFREE |
The rs9939609 A allele, which was associated with higher BMI in the sample, was inversely associated with overall (odds ratio (OR) versus all controls = 0.93; 95% confidence interval (CI): 0.85-1.02 p = 0.12 per allele) and low-grade (OR = 0.90; 0.81-0.99 p = 0.03 per allele) prostate cancer risk, but positively associated with high-grade cancer among cases (OR high- versus low-grade cancer = 1.16; 0.99-1.37 p = 0.07 per allele).
|
20976066 |
2010 |
|
rs9939609
|
|
|
0.790 |
GeneticVariation |
BEFREE |
A cross-sectional study examined 4839 subjects in the population-based Malmö Diet and Cancer study with dietary data (from a modified diet history method) and information on the genetic variant FTO (rs9939609).
|
19726594 |
2009 |
|
rs1477196
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In addition, overall, there was no significant association between <i>FTO</i> rs1477196 variant and cancer risk regardless of adjustment for body mass index.
|
28881622 |
2017 |
|
rs1121980
|
|
|
0.020 |
GeneticVariation |
BEFREE |
To date it has been observed that variants rs9939609, rs17817449, rs8050136, rs1477196, rs6499640, rs16953002, rs11075995 and rs1121980 are associated with the risk of developing cancer.
|
25387436 |
2015 |
|
rs1477196
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The homocysteine level was not associated with either MTHFR C677T or A1298C, nor with FTO rs1477196, but was inversely correlated with folate status in cancer cases (p<0.0001) and tended to be higher in patients with the MTHFR 677TT genotype.
|
24023349 |
2013 |
|
rs1121980
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The FTO variant rs1121980 was genotyped in 20,374 participants (39-79 y of age) from the European Prospective Investigation into Cancer and Nutrition-Norfolk Study, an ethnically homogeneous population-based cohort.
|
19553294 |
2009 |
|
rs8050136
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Participants from the Tübingen Family study (n = 2245) and the Malmö Diet and Cancer study (n = 2921) were genotyped for FTO SNP rs8050136 and ANKK1 SNP rs1800497.
|
27600277 |
2016 |
|
rs11075995
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To date it has been observed that variants rs9939609, rs17817449, rs8050136, rs1477196, rs6499640, rs16953002, rs11075995 and rs1121980 are associated with the risk of developing cancer.
|
25387436 |
2015 |
|
rs16953002
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To date it has been observed that variants rs9939609, rs17817449, rs8050136, rs1477196, rs6499640, rs16953002, rs11075995 and rs1121980 are associated with the risk of developing cancer.
|
25387436 |
2015 |