|
rs25487
|
|
|
0.090 |
GeneticVariation |
BEFREE |
We also observed that the rs25487 mutation was significantly increased within the cervical cancer</span> population.
|
30616520 |
2019 |
|
rs25487
|
|
|
0.090 |
GeneticVariation |
BEFREE |
In view of the exiting heterogeneity, we did subgroup analysis stratified</span> by ethnicity, resulting in the fact that the Arg39</span>9Gln polymorphism was related to the decreased risk of cervical cancer.
|
27903984 |
2017 |
|
rs25487
|
|
|
0.090 |
GeneticVariation |
BEFREE |
This meta-analysis showed that the XRCC1 Arg399Gln GA variant might be risk alleles for cervical cancer susceptibility in the Chinese population, and further studies in other ethnic groups are required to arrive at definite conclusions.
|
27487002 |
2017 |
|
rs25487
|
|
|
0.090 |
GeneticVariation |
BEFREE |
This meta-analysis provides strongly statistical evidence for the association between rs1799782 and cervical cancer risk, as well as its association with rs25487 only in Asian populations.
|
24057881 |
2014 |
|
rs25487
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The XRCC1 Arg399Gln genetic variants were identified by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) in patients with advanced cervical cancer (n=189) and controls (n=308).
|
21928248 |
2012 |
|
rs25487
|
|
|
0.090 |
GeneticVariation |
BEFREE |
This meta-analysis suggests that Arg194Trp polymorphism may be associated with CC risk, Arg399Gln polymorphism might be a low-penetrent risk factor for CC only in Asians, and there may be no association between Arg280His polymorphism and CC risk.
|
22984511 |
2012 |
|
rs25487
|
|
|
0.090 |
GeneticVariation |
BEFREE |
We found that the Arg194Trp polymorphism (Trp vs. Arg, OR=1.342, 95% CI: 1.176) was associated with increased risk of cervical cancer, while no significant association was found with Arg280His (His vs. Arg, OR=1.059, 95% CI: 0.863, 1.299) or Arg399Gln (Gln vs. Arg, OR=1.144, 95% CI: 0.938, 1.394).
|
23464469 |
2012 |
|
rs25487
|
|
|
0.090 |
GeneticVariation |
BEFREE |
XRCC1 R399Q polymorphism is associated with response to platinum-based neoadjuvant chemotherapy in bulky cervical cancer.
|
16875718 |
2006 |
|
rs25487
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Association of XRCC1 Arg399Gln and OGG1 Ser326Cys polymorphisms with the risk of cervical cancer in Japanese subjects.
|
15990162 |
2005 |
|
rs1799782
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Taken together, there was no obvious association between the Arg194Trp or Arg280His polymorphism and cervical cancer risk.
|
27903984 |
2017 |
|
rs25489
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Taken together, there was no obvious association between the Arg194Trp or Arg280His polymorphism and cervical cancer risk.
|
27903984 |
2017 |
|
rs25489
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Moreover, the AA genotype at rs25489 was determined to be a risk factor for cervical cancer etiology (homozygous model, OR 2.91, 95%CI, 1.17-7.26; recessive model, OR 3.16, 95%CI 1.91-5.24).
|
28415705 |
2017 |
|
rs1799782
|
|
|
0.050 |
GeneticVariation |
BEFREE |
This meta-analysis provides strongly statistical evidence for the association between rs1799782 and cervical cancer risk, as well as its association with rs25487 only in Asian populations.
|
24057881 |
2014 |
|
rs25489
|
|
|
0.050 |
GeneticVariation |
BEFREE |
However, there was no significant association between rs25489 and cervical cancer risk.
|
24057881 |
2014 |
|
rs1799782
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The Arg194Trp polymorphism of XRCC1 increases risk of cervical cancer; the variant 399Gln allele predicts poor response to platinum-based chemotherapy, while the Arg194Trp polymorphism indicates a good response.
|
23464469 |
2012 |
|
rs1799782
|
|
|
0.050 |
GeneticVariation |
BEFREE |
This meta-analysis suggests that Arg194Trp polymorphism may be associated with CC risk, Arg399Gln polymorphism might be a low-penetrent risk factor for CC only in Asians, and there may be no association between Arg280His polymorphism and CC risk.
|
22984511 |
2012 |
|
rs25489
|
|
|
0.050 |
GeneticVariation |
BEFREE |
This meta-analysis suggests that Arg194Trp polymorphism may be associated with CC risk, Arg399Gln polymorphism might be a low-penetrent risk factor for CC only in Asians, and there may be no association between Arg280His polymorphism and CC risk.
|
22984511 |
2012 |
|
rs25489
|
|
|
0.050 |
GeneticVariation |
BEFREE |
We found that the Arg194Trp polymorphism (Trp vs. Arg, OR=1.342, 95% CI: 1.176) was associated with increased risk of cervical cancer, while no significant association was found with Arg280His (His vs. Arg, OR=1.059, 95% CI: 0.863, 1.299) or Arg399Gln (Gln vs. Arg, OR=1.144, 95% CI: 0.938, 1.394).
|
23464469 |
2012 |
|
rs1799782
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The genotypes of XRCC1 Arginine194Tryptophan and GGH-401Cytosine/Thymine were associated with the response to NAC in patients with cervical cancer.
|
18851872 |
2008 |
|
rs3213245
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In summary, the findings indicated that the functional <i>XRCC1</i> SNP rs3213245 was associated with the risk of cervical cancer based on the Sp1/Krox-20 switch.
|
29156789 |
2017 |