Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1076560
rs1076560
DRD2
0.020 GeneticVariation BEFREE One functional single nucleotide polymorphism in dopamine receptor D2 (DRD2), rs1076560, is involved in regulating splicing of the gene and alters the ratio of DRD2 isoforms located pre- and postsynaptically. rs1076560 has been previously associated with cocaine abuse and we set out to confirm this association in a sample of European American (EA) (n = 336) and African American (AA) (n = 1034) cocaine addicts and EA (n = 656) and AA (n = 668) controls. 24359476

2014
dbSNP: rs1076560
rs1076560
DRD2
0.020 GeneticVariation BEFREE Our results confirm the role of rs2283265/rs1076560 in D2 alternative splicing and support a strong role in susceptibility to cocaine abuse. 21150907

2011
dbSNP: rs1500
rs1500
CRHBP
0.010 GeneticVariation BEFREE Reduction in cocaine abuse among MMT patients may be mediated by a genetic effect in a stress-related gene (CRHBP SNP rs1500 minor C allele). 30844877

2020
dbSNP: rs2283265
rs2283265
DRD2
0.010 GeneticVariation BEFREE Our results confirm the role of rs2283265/rs1076560 in D2 alternative splicing and support a strong role in susceptibility to cocaine abuse. 21150907

2011