Gene: IFNG-AS1 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs7134599
rs7134599
IFNG-AS1 ; LOC107984526
A 0.800 GeneticVariation GWASCAT Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. 21297633

2011
dbSNP: rs7134599
rs7134599
IFNG-AS1 ; LOC107984526
A 0.800 GeneticVariation GWASDB Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. 21297633

2011
dbSNP: rs1558744
rs1558744
IFNG-AS1 ; LOC107984526
A 0.800 GeneticVariation GWASCAT Genome-wide association identifies multiple ulcerative colitis susceptibility loci. 20228799

2010
dbSNP: rs1558744
rs1558744
IFNG-AS1 ; LOC107984526
A 0.800 GeneticVariation GWASDB Genome-wide association identifies multiple ulcerative colitis susceptibility loci. 20228799

2010
dbSNP: rs1558744
rs1558744
IFNG-AS1 ; LOC107984526
A 0.800 GeneticVariation GWASDB In an analysis that controlled for gender and population structure, ulcerative colitis loci attaining genome-wide significance and subsequent replication in two independent populations were identified on chromosomes 1p36 (rs6426833, combined P = 5.1 x 10(-13), combined odds ratio OR = 0.73) and 12q15 (rs1558744, combined P = 2.5 x 10(-12), combined OR = 1.35). 19122664

2009
dbSNP: rs1558744
rs1558744
IFNG-AS1 ; LOC107984526
A 0.800 GeneticVariation GWASCAT In an analysis that controlled for gender and population structure, ulcerative colitis loci attaining genome-wide significance and subsequent replication in two independent populations were identified on chromosomes 1p36 (rs6426833, combined P = 5.1 x 10(-13), combined odds ratio OR = 0.73) and 12q15 (rs1558744, combined P = 2.5 x 10(-12), combined OR = 1.35). 19122664

2009
dbSNP: rs2870946
rs2870946
IL26 ; IFNG-AS1 ; LOC105369818
G 0.800 GeneticVariation GWASCAT Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study. 19122664

2009
dbSNP: rs2870946
rs2870946
IL26 ; IFNG-AS1 ; LOC105369818
G 0.800 GeneticVariation GWASDB Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study. 19122664

2009
dbSNP: rs11614178
rs11614178
IFNG-AS1 ; LOC107984526
0.700 GeneticVariation GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908

2017
dbSNP: rs11614178
rs11614178
IFNG-AS1 ; LOC107984526
0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007

2016
dbSNP: rs7134472
rs7134472
IFNG-AS1 ; LOC107984526
A 0.700 GeneticVariation GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919

2015
dbSNP: rs1861494
rs1861494
IFNG ; IFNG-AS1
0.010 GeneticVariation BEFREE Peripheral T cells of UC and Crohn's disease (CD) patients were genotyped for rs1861494 and analyzed for allele-specific and IFNG promoter methylation. 25171510

2014
dbSNP: rs2430561
rs2430561
IFNG ; IFNG-AS1
0.010 GeneticVariation BEFREE Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05). 24776844

2014