Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1045642
rs1045642
ABCB1
0.010 GeneticVariation BEFREE One hundred twenty-seven cases of seizure (86 GS and 41 FS) patients were analyzed for MDR1 C3435T and GABRG2 C588T gene polymorphisms using restriction fragment length polymorphism-polymerase chain reaction.Serum PHT levels were analyzed. 22239287

2012
dbSNP: rs114444506
rs114444506
ANO3 ; LOC105376598 ; ANO3-AS1
C 0.700 GeneticVariation GWASCAT Furthermore, four loci were associated with febrile seizures in general, implicating the sodium channel genes SCN1A (rs6432860: P = 2.2 × 10(-16)) and SCN2A (rs3769955: P = 3.1 × 10(-10)), a TMEM16 family gene (ANO3; rs114444506: P = 3.7 × 10(-20)) and a region associated with magnesium levels (12q21.33; rs11105468: P = 3.4 × 10(-11)). 25344690

2014
dbSNP: rs886041065
rs886041065
ASXL2
T 0.700 CausalMutation CLINVAR

dbSNP: rs606231435
rs606231435
ATP1A3
T 0.700 CausalMutation CLINVAR

dbSNP: rs6265
rs6265
BDNF ; BDNF-AS
0.010 GeneticVariation BEFREE Brain-derived neurotrophic factor (BDNF) Val66Met polymorphisms in febrile seizures. 15279867

2004
dbSNP: rs759834365
rs759834365
BDNF ; BDNF-AS
0.010 GeneticVariation BEFREE Brain-derived neurotrophic factor (BDNF) Val66Met polymorphisms in febrile seizures. 15279867

2004
dbSNP: rs121909323
rs121909323
CACNA1A
A 0.700 CausalMutation CLINVAR CACNA1A haploinsufficiency causes cognitive impairment, autism and epileptic encephalopathy with mild cerebellar symptoms. 25735478

2015
dbSNP: rs1555745467
rs1555745467
CACNA1A
A 0.700 GeneticVariation CLINVAR

dbSNP: rs786200962
rs786200962
CACNA1A
G 0.700 CausalMutation CLINVAR CACNA1A haploinsufficiency causes cognitive impairment, autism and epileptic encephalopathy with mild cerebellar symptoms. 25735478

2015
dbSNP: rs786200963
rs786200963
CACNA1A
T 0.700 GeneticVariation CLINVAR CACNA1A haploinsufficiency causes cognitive impairment, autism and epileptic encephalopathy with mild cerebellar symptoms. 25735478

2015
dbSNP: rs2724384
rs2724384
CD46
A 0.700 GeneticVariation GWASCAT Common variants associated with general and MMR vaccine-related febrile seizures. 25344690

2014
dbSNP: rs201439531
rs201439531
CHAT
G 0.700 CausalMutation CLINVAR

dbSNP: rs769234940
rs769234940
CHAT
T 0.700 CausalMutation CLINVAR

dbSNP: rs61738009
rs61738009
CPA6 ; LOC102724708
0.010 GeneticVariation BEFREE Screening all exons of CPA6 in unrelated patients with partial epilepsy (n = 195) and FS (n = 145) revealed a new heterozygous missense mutation c.799G>A (p.Gly267Arg) in three TLE patients. 21922598

2012
dbSNP: rs1398830127
rs1398830127
GABBR1
0.010 GeneticVariation BEFREE Our results indicate that TLE preceded by FS is not associated with the polymorphisms or mutations in the GABBR1 gene, including the G1465A polymorphism. 15799783

2005
dbSNP: rs1805057
rs1805057
GABBR1
0.010 GeneticVariation BEFREE Our results indicate that TLE preceded by FS is not associated with the polymorphisms or mutations in the GABBR1 gene, including the G1465A polymorphism. 15799783

2005
dbSNP: rs211037
rs211037
GABRG2
0.050 GeneticVariation BEFREE One hundred twenty-seven cases of seizure (86 GS and 41 FS) patients were analyzed for MDR1 C3435T and GABRG2 C588T gene polymorphisms using restriction fragment length polymorphism-polymerase chain reaction.Serum PHT levels were analyzed. 22239287

2012
dbSNP: rs211037
rs211037
GABRG2
0.050 GeneticVariation BEFREE GABRG2, rs211037 is associated with epilepsy susceptibility, but not with antiepileptic drug resistance and febrile seizures. 24061200

2013
dbSNP: rs211037
rs211037
GABRG2
0.050 GeneticVariation BEFREE GABRG2 rs211037 TT homozygotes and T allele variants have an increased risk for developing febrile seizures.</span> 29379546

2018
dbSNP: rs211037
rs211037
GABRG2
0.050 GeneticVariation BEFREE This study showed significant association of GABRG2 rs211037 with susceptibility to FS, caused by two studies with small sample sizes, however the possibility of false positive results due to the effect of significant studies for FS cannot be excluded. 23140995

2013
dbSNP: rs211037
rs211037
GABRG2
0.050 GeneticVariation BEFREE In conclusion, rs211037 alone may be a risk factor for FS, partial seizure, and SE, and in linkage disequilibrium with rs210987 can contribute to FS and SE in Asians, particularly in Chinese. 26452361

2016
dbSNP: rs121909673
rs121909673
GABRG2
0.010 GeneticVariation BEFREE Heterozygous gamma-aminobutyric acid A receptor γ2 subunit (R43Q) mutation may have an effect in the development of febrile seizures. 24630281

2014
dbSNP: rs210987
rs210987
GABRG2
0.010 GeneticVariation BEFREE In conclusion, rs211037 alone may be a risk factor for FS, partial seizure, and SE, and in linkage disequilibrium with rs210987 can contribute to FS and SE in Asians, particularly in Chinese. 26452361

2016
dbSNP: rs211014
rs211014
GABRG2
0.010 GeneticVariation BEFREE Compared with the single-nucleotide polymorphism rs211014 CC genotype, the odds ratio for developing febrile seizures in individuals with the single-nucleotide polymorphism rs211014 AA genotype was 4.05 (P < .005). 17641256

2007
dbSNP: rs267606837
rs267606837
GABRG2
0.010 GeneticVariation BEFREE GABAA receptor biogenesis is impaired by the γ2 subunit febrile seizure-associated mutation, GABRG2(R177G). 24874541

2014