|
rs145204276
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association between indel polymorphism (rs145204276) in the promoter region of lncRNA GAS5 and the risk of febrile convulsion.
|
30656683 |
2019 |
|
rs1564365418
|
|
T |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs273259
|
|
A |
0.710 |
GeneticVariation |
GWASCAT |
Two loci were distinctly associated with MMR-related febrile seizures, harboring the interferon-stimulated gene IFI44L (rs273259: P = 5.9 × 10(-12) versus controls, P = 1.2 × 10(-9) versus MMR-unrelated febrile seizures) and the measles virus receptor CD46 (rs1318653: P = 9.6 × 10(-11) versus controls, P = 1.6 × 10(-9) versus MMR-unrelated febrile seizures).
|
25344690 |
2014 |
|
rs273259
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Two loci were distinctly associated with MMR-related febrile seizures, harboring the interferon-stimulated gene IFI44L (rs273259: P = 5.9 × 10(-12) versus controls, P = 1.2 × 10(-9) versus MMR-unrelated febrile seizures) and the measles virus receptor CD46 (rs1318653: P = 9.6 × 10(-11) versus controls, P = 1.6 × 10(-9) versus MMR-unrelated febrile seizures).
|
25344690 |
2014 |
|
rs1800587
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No association was observed between the IL-1B rs1143627, IL-1B rs1143634, and IL-1A rs1800587 polymorphisms and FS risk.
|
29808330 |
2018 |
|
rs16944
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The findings of our meta-analysis suggest that the IL-1B rs16944 polymorphism may be an important genetic determinant for FS in Caucasian and Asian populations.
|
29808330 |
2018 |
|
rs16944
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Expression of these cytokines can be modulated by polymorphisms such as rs16944 and rs1800629, respectively, both of which have been associated with febrile seizures (FS) and MTLE-HS development.
|
28675059 |
2018 |
|
rs1143627
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No association was observed between the IL-1B rs1143627, IL-1B rs1143634, and IL-1A rs1800587 polymorphisms and FS risk.
|
29808330 |
2018 |
|
rs1143634
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No association was observed between the IL-1B rs1143627, IL-1B rs1143634, and IL-1A rs1800587 polymorphisms and FS risk.
|
29808330 |
2018 |
|
rs11105468
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Furthermore, four loci were associated with febrile seizures in general, implicating the sodium channel genes SCN1A (rs6432860: P = 2.2 × 10(-16)) and SCN2A (rs3769955: P = 3.1 × 10(-10)), a TMEM16 family gene (ANO3; rs114444506: P = 3.7 × 10(-20)) and a region associated with magnesium levels (12q21.33; rs11105468: P = 3.4 × 10(-11)).
|
25344690 |
2014 |
|
rs61752717
|
|
|
0.010 |
GeneticVariation |
BEFREE |
MEFV gene mutations, especially M694V mutation, are positively associated with FSs.
|
24668705 |
2014 |
|
rs2910164
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of genetic polymorphism of pre-microRNA-146a rs2910164 and serum high-mobility group box 1 with febrile seizures in Egyptian children.
|
25319229 |
2015 |
|
rs1318653
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Two loci were distinctly associated with MMR-related febrile seizures, harboring the interferon-stimulated gene IFI44L (rs273259: P = 5.9 × 10(-12) versus controls, P = 1.2 × 10(-9) versus MMR-unrelated febrile seizures) and the measles virus receptor CD46 (rs1318653: P = 9.6 × 10(-11) versus controls, P = 1.6 × 10(-9) versus MMR-unrelated febrile seizures).
|
25344690 |
2014 |
|
rs1318653
|
|
T |
0.710 |
GeneticVariation |
GWASCAT |
Two loci were distinctly associated with MMR-related febrile seizures, harboring the interferon-stimulated gene IFI44L (rs273259: P = 5.9 × 10(-12) versus controls, P = 1.2 × 10(-9) versus MMR-unrelated febrile seizures) and the measles virus receptor CD46 (rs1318653: P = 9.6 × 10(-11) versus controls, P = 1.6 × 10(-9) versus MMR-unrelated febrile seizures).
|
25344690 |
2014 |
|
rs755604487
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs13306038
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To investigate possible association of FS with single nucleotide polymorphisms (SNPs) in prostaglandin-endoperoxide synthase-2 (prostaglandin G/H synthase-2; PTGS2/cyclooxygenase-2; COX2) gene involving in thermoregulatory pathway, eight SNPs, rs689465, rs689466, rs20417, rs13306038, rs201931599, rs689470, rs4648306 and rs4648308, along with 2 previously reported variations in IL1RN (86-bp VNTR) and IL10 (rs1900872) were genotyped and utilized for case-control association studies on 35 FS and 31 non-FS controls.
|
27871023 |
2017 |
|
rs201931599
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To investigate possible association of FS with single nucleotide polymorphisms (SNPs) in prostaglandin-endoperoxide synthase-2 (prostaglandin G/H synthase-2; PTGS2/cyclooxygenase-2; COX2) gene involving in thermoregulatory pathway, eight SNPs, rs689465, rs689466, rs20417, rs13306038, rs201931599, rs689470, rs4648306 and rs4648308, along with 2 previously reported variations in IL1RN (86-bp VNTR) and IL10 (rs1900872) were genotyped and utilized for case-control association studies on 35 FS and 31 non-FS controls.
|
27871023 |
2017 |
|
rs4648306
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To investigate possible association of FS with single nucleotide polymorphisms (SNPs) in prostaglandin-endoperoxide synthase-2 (prostaglandin G/H synthase-2; PTGS2/cyclooxygenase-2; COX2) gene involving in thermoregulatory pathway, eight SNPs, rs689465, rs689466, rs20417, rs13306038, rs201931599, rs689470, rs4648306 and rs4648308, along with 2 previously reported variations in IL1RN (86-bp VNTR) and IL10 (rs1900872) were genotyped and utilized for case-control association studies on 35 FS and 31 non-FS controls.
|
27871023 |
2017 |
|
rs4648308
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To investigate possible association of FS with single nucleotide polymorphisms (SNPs) in prostaglandin-endoperoxide synthase-2 (prostaglandin G/H synthase-2; PTGS2/cyclooxygenase-2; COX2) gene involving in thermoregulatory pathway, eight SNPs, rs689465, rs689466, rs20417, rs13306038, rs201931599, rs689470, rs4648306 and rs4648308, along with 2 previously reported variations in IL1RN (86-bp VNTR) and IL10 (rs1900872) were genotyped and utilized for case-control association studies on 35 FS and 31 non-FS controls.
|
27871023 |
2017 |
|
rs689470
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To investigate possible association of FS with single nucleotide polymorphisms (SNPs) in prostaglandin-endoperoxide synthase-2 (prostaglandin G/H synthase-2; PTGS2/cyclooxygenase-2; COX2) gene involving in thermoregulatory pathway, eight SNPs, rs689465, rs689466, rs20417, rs13306038, rs201931599, rs689470, rs4648306 and rs4648308, along with 2 previously reported variations in IL1RN (86-bp VNTR) and IL10 (rs1900872) were genotyped and utilized for case-control association studies on 35 FS and 31 non-FS controls.
|
27871023 |
2017 |
|
rs20417
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To investigate possible association of FS with single nucleotide polymorphisms (SNPs) in prostaglandin-endoperoxide synthase-2 (prostaglandin G/H synthase-2; PTGS2/cyclooxygenase-2; COX2) gene involving in thermoregulatory pathway, eight SNPs, rs689465, rs689466, rs20417, rs13306038, rs201931599, rs689470, rs4648306 and rs4648308, along with 2 previously reported variations in IL1RN (86-bp VNTR) and IL10 (rs1900872) were genotyped and utilized for case-control association studies on 35 FS and 31 non-FS controls.
|
27871023 |
2017 |
|
rs689465
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To investigate possible association of FS with single nucleotide polymorphisms (SNPs) in prostaglandin-endoperoxide synthase-2 (prostaglandin G/H synthase-2; PTGS2/cyclooxygenase-2; COX2) gene involving in thermoregulatory pathway, eight SNPs, rs689465, rs689466, rs20417, rs13306038, rs201931599, rs689470, rs4648306 and rs4648308, along with 2 previously reported variations in IL1RN (86-bp VNTR) and IL10 (rs1900872) were genotyped and utilized for case-control association studies on 35 FS and 31 non-FS controls.
|
27871023 |
2017 |
|
rs689466
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A single SNP (rs689466) localized at 5'-1192 of the PTGS2 gene exhibited significant association with FS (p=0.045) based on case-control allelic association analyses.
|
27871023 |
2017 |
|
rs1057518853
|
|
TA |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs1553553485
|
|
C |
0.700 |
CausalMutation |
CLINVAR |
|
|
|