|
rs662
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This meta-analysis suggests that the association between the PON1 rs662 polymorphism and CHD may partly be mediated by abnormal Ox-LDL and lipid levels caused by the R allele.
|
30545386 |
2018 |
|
rs662
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This meta-analysis suggests that the PON1 Q192R polymorphism has a weak association with CHD risk in Chinese.
|
29952962 |
2018 |
|
rs854560
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Relationship between rs854560 <i>PON1</i> Gene Polymorphism and Tobacco Smoking with Coronary Artery Disease.
|
29118461 |
2017 |
|
rs662
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The activity of PON1 is decreased in patients with coronary artery disease, myocardial infarction or chronic kidney disease. rs662 and rs854560 are single nucleotide polymorphisms (SNPs) associated with PON1 activity and 10-year cardiovascular mortality of patients with stable coronary artery disease.
|
25155309 |
2016 |
|
rs854560
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The association of paraoxonase 1 gene L55M polymorphism with the extent and severity of coronary artery disease in the Turkish population and its dependence on gender.
|
26467378 |
2016 |
|
rs854560
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The activity of PON1 is decreased in patients with coronary artery disease, myocardial infarction or chronic kidney disease. rs662 and rs854560 are single nucleotide polymorphisms (SNPs) associated with PON1 activity and 10-year cardiovascular mortality of patients with stable coronary artery disease.
|
25155309 |
2016 |
|
rs662
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Two PON1 SNPs, rs662 and rs3735590, were found to significantly interact with cigarette smoking to modulate the risk of CHD in the Singaporean Chinese population.
|
25746376 |
2015 |
|
rs662
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Association between PON1 rs662 polymorphism and coronary artery disease.
|
24918121 |
2014 |
|
rs662
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Association of paraoxonase1 gene Q192R polymorphism and apolipoprotein B in Asian Indian women with coronary artery disease risk.
|
23171143 |
2013 |
|
rs662
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The Q192R polymorphism of the paraoxonase 1 gene is a risk factor for coronary artery disease in Saudi subjects.
|
23625196 |
2013 |
|
rs662
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Interaction of folate intake and the paraoxonase Q192R polymorphism with risk of incident coronary heart disease and ischemic stroke: the atherosclerosis risk in communities study.
|
21982484 |
2011 |
|
rs662
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We tested the clinical relevance of the PON1 Q192R genotype in a population of individuals with coronary artery disease who underwent stent implantation and received clopidogrel therapy.
|
21170047 |
2011 |
|
rs662
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A preliminary study of human paraoxonase and PON 1 L/M55-PON 1 Q/R 192 polymorphisms in Turkish patients with coronary artery disease.
|
19226538 |
2009 |
|
rs854560
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A preliminary study of human paraoxonase and PON 1 L/M55-PON 1 Q/R 192 polymorphisms in Turkish patients with coronary artery disease.
|
19226538 |
2009 |
|
rs854560
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In parallel nested case-control studies, the prospective associations between PON1 polymorphisms Q192R and L55M and incident CHD were examined among participants in the Nurses' Health and Health Professionals Follow-up Studies.
|
19443958 |
2009 |
|
rs662
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We conclude that the Q192R polymorphism of PON1 significantly modulates the HDL-C response to simvastatin in Chinese patients with CHD.
|
18430057 |
2008 |
|
rs662
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Paraoxonase-1 (PON1) activity, but not PON1(Q192R) phenotype, is a predictor of coronary artery disease in a middle-aged Serbian population.
|
17032132 |
2006 |
|
rs662
|
|
|
0.100 |
GeneticVariation |
BEFREE |
There is no robust evidence that the PON1 Q192R polymorphism is associated with CHD risk in Caucasian women or men.
|
15214960 |
2004 |
|
rs662
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Using self-reported data on ischemic heart disease to evaluate the impact of the PON 192Q/R polymorphism on susceptibility to CHD, we found only a nonsignificant trend of 192RR homozygosity in women being a risk factor.
|
15241482 |
2004 |
|
rs662
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The weak overall association between the Q192R polymorphism and CHD is of uncertain relevance, particularly since there was no significant association among the larger studies which should be less prone to selective publication.
|
15001326 |
2004 |
|
rs854560
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In contrast to previous suggestions, this meta-analysis shows no significant association of CHD with the L55M or T(-107)C polymorphism in PON1 or with the S311C polymorphism in PON2.
|
15001326 |
2004 |
|
rs854560
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Two coding polymorphisms, 55M/L and 192Q/R, and a promoter variant, -107C/T, has been extensively studied with respect to susceptibility to CHD.
|
15241482 |
2004 |
|
rs854560
|
|
|
0.100 |
GeneticVariation |
BEFREE |
PON1 M/L55 mutation protects high-risk patients against coronary artery disease.
|
14996478 |
2004 |
|
rs662
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Different pattern of association of paraoxonase Gln192-->Arg polymorphism with sporadic late-onset Alzheimer's disease and coronary artery disease.
|
12618290 |
2003 |
|
rs662
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Two cSNPs in PON1 (L55M and Q192R) and one in PON2 (S311C) have been implicated as independent risk factors for coronary heart disease (CHD) in some, but not all, studies.
|
14636952 |
2003 |