Gene: IL10 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3024493
rs3024493
IL10 ; IL19
0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007

2016
dbSNP: rs145922845
rs145922845
IL10 ; IL19
0.030 GeneticVariation BEFREE The interleukin-10 Gly15Arg mutation is rare in patients with Crohn's disease, and is not associated with the disease in the Netherlands. 15843082

2005
dbSNP: rs145922845
rs145922845
IL10 ; IL19
0.030 GeneticVariation BEFREE A Gly15Arg mutation in the leader sequence of IL-10 was found in a multiple CD-affected family. 12825869

2003
dbSNP: rs145922845
rs145922845
IL10 ; IL19
0.030 GeneticVariation BEFREE Screening of the coding region of the IL-10 gene by polymerase chain reaction--single strand conformation polymorphism (PCR-SSCP) analysis revealed a rare sequence variation in exon 1 leading to an amino acid exchange (G-->A; G15R) in two patients with CD and five healthy controls. 11271474

2000
dbSNP: rs1800871
rs1800871
IL10 ; IL19
0.020 GeneticVariation BEFREE Single nucleotide polymorphisms (SNPs) that affect IL-10 production, such as rs1800896 (G/A) at position -1082 and rs1800871 (C/T) at position -819 in the promoter region of the IL10 gene, have been associated with CD and/or UC, but the results were inconsistent. 27558476

2016
dbSNP: rs1800896
rs1800896
IL10 ; IL19
0.020 GeneticVariation BEFREE Single nucleotide polymorphisms (SNPs) that affect IL-10 production, such as rs1800896 (G/A) at position -1082 and rs1800871 (C/T) at position -819 in the promoter region of the IL10 gene, have been associated with CD and/or UC, but the results were inconsistent. 27558476

2016
dbSNP: rs1800896
rs1800896
IL10 ; IL19
0.020 GeneticVariation BEFREE We demonstrated an association with CD for SNPs rs3024505 and rs1800896, and phenotypic analysis indicated an association of rs3024505 with an early age at first diagnosis, stricturing CD behavior, and requirement for bowel resection. 21354456

2011
dbSNP: rs1800871
rs1800871
IL10 ; IL19
0.020 GeneticVariation BEFREE Of the five IL-10 tag-SNPs, rs2222202 (C/T) (P = 0.03) and rs1800871 (C/T) (P = 0.05) showed significant allelic associations with CD. 19210299

2009
dbSNP: rs2222202
rs2222202
IL10 ; IL19
0.010 GeneticVariation BEFREE Of the five IL-10 tag-SNPs, rs2222202 (C/T) (P = 0.03) and rs1800871 (C/T) (P = 0.05) showed significant allelic associations with CD. 19210299

2009