|
rs1801282
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.
|
24971461 |
2014 |
|
rs1801282
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The Pro12Ala polymorphism showed significant association with CD when the frequencies of the homozygous variants (Pro/Pro vs. Ala/Ala) were compared.
|
21710534 |
2012 |
|
rs1801282
|
|
|
0.050 |
GeneticVariation |
BEFREE |
PPARγ Pro12Ala variant homozygotes appear to be protected from the development of Crohn's disease (CD) in European Caucasians.
|
23256116 |
2012 |
|
rs1801282
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Polymerase Chain Reaction (PCR) and Restriction Fragment Length Polymorphism (RFLP) techniques were used to analyze Caspase9+93C/T, FasLigand-843C/T, Peroxisome Proliferator-Activated Receptor gamma+161C/T and Peroxisome Proliferator-Activated Receptor gamma Pro12Ala SNPs in 99 patients with CD and 116 healthy controls.
|
20650551 |
2010 |
|
rs1801282
|
|
|
0.050 |
GeneticVariation |
BEFREE |
These results suggest that Pro12Ala polymorphism in the PPAR-gamma gene relates neither to the risk of the development of inflammatory bowel disease nor to the clinical subtypes of CD in the Turkish population.
|
19104705 |
2008 |
|
rs1805192
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The Pro12Ala polymorphism showed significant association with CD when the frequencies of the homozygous variants (Pro/Pro vs. Ala/Ala) were compared.
|
21710534 |
2012 |
|
rs1805192
|
|
|
0.040 |
GeneticVariation |
BEFREE |
PPARγ Pro12Ala variant homozygotes appear to be protected from the development of Crohn's disease (CD) in European Caucasians.
|
23256116 |
2012 |
|
rs1805192
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Polymerase Chain Reaction (PCR) and Restriction Fragment Length Polymorphism (RFLP) techniques were used to analyze Caspase9+93C/T, FasLigand-843C/T, Peroxisome Proliferator-Activated Receptor gamma+161C/T and Peroxisome Proliferator-Activated Receptor gamma Pro12Ala SNPs in 99 patients with CD and 116 healthy controls.
|
20650551 |
2010 |
|
rs1805192
|
|
|
0.040 |
GeneticVariation |
BEFREE |
These results suggest that Pro12Ala polymorphism in the PPAR-gamma gene relates neither to the risk of the development of inflammatory bowel disease nor to the clinical subtypes of CD in the Turkish population.
|
19104705 |
2008 |
|
rs145566594
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found that both CD subjects and mice with ATG16L1T300A (T300A; a prevalent CD susceptibility allele) developed Paneth cell defects triggered by tobacco smoke.
|
30137026 |
2018 |