rs2066844
|
|
|
1.000 |
GeneticVariation |
GWASCAT |
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.
|
28067908 |
2017 |
rs2066844
|
|
|
1.000 |
GeneticVariation |
UNIPROT |
Additionally, we show that the interaction of 8 NIPs is compromised with the 3 main CD associated NOD2 mutants (R702W, G908R and 1007fs).
|
27812135 |
2016 |
rs2066845
|
|
|
1.000 |
GeneticVariation |
GWASCAT |
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
|
26974007 |
2016 |
rs2066845
|
|
|
1.000 |
GeneticVariation |
UNIPROT |
Additionally, we show that the interaction of 8 NIPs is compromised with the 3 main CD associated NOD2 mutants (R702W, G908R and 1007fs).
|
27812135 |
2016 |
rs2066844
|
|
|
1.000 |
GeneticVariation |
UNIPROT |
Interaction between NOD2 and CARD9 involves the NOD2 NACHT and the linker region between the NOD2 CARDs and NACHT domain.
|
24960071 |
2014 |
rs2066844
|
|
|
1.000 |
GeneticVariation |
UNIPROT |
The molecular chaperone HSP70 binds to and stabilizes NOD2, an important protein involved in Crohn disease.
|
24790089 |
2014 |
rs2066845
|
|
|
1.000 |
GeneticVariation |
UNIPROT |
The molecular chaperone HSP70 binds to and stabilizes NOD2, an important protein involved in Crohn disease.
|
24790089 |
2014 |
rs2066845
|
|
|
1.000 |
GeneticVariation |
UNIPROT |
Interaction between NOD2 and CARD9 involves the NOD2 NACHT and the linker region between the NOD2 CARDs and NACHT domain.
|
24960071 |
2014 |
rs2066845
|
|
|
1.000 |
GeneticVariation |
GWASDB |
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.
|
18587394 |
2008 |
rs2066844
|
|
|
1.000 |
GeneticVariation |
GWASDB |
Systematic association mapping identifies NELL1 as a novel IBD disease gene.
|
17684544 |
2007 |
rs2066844
|
|
|
1.000 |
GeneticVariation |
GWASDB |
Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci.
|
17804789 |
2007 |
rs2066845
|
|
|
1.000 |
GeneticVariation |
GWASDB |
Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci.
|
17804789 |
2007 |
rs2066845
|
|
|
1.000 |
GeneticVariation |
GWASDB |
Systematic association mapping identifies NELL1 as a novel IBD disease gene.
|
17684544 |
2007 |
rs2066844
|
|
|
1.000 |
GeneticVariation |
UNIPROT |
We performed a limited DNA sequence analysis of the CARD15 gene in 89 patients with Crohn's disease (CD), 19 patients with ulcerative colitis (UC), and three patients with indeterminate colitis (IC), who were heterozygous carriers of one of the common CARD15 mutations [c.2104C>T (p.R702W), c.2722G>C (p.G908R), or c.3019_3020insC (p.Leu1007fsX1008)], the c.2462+10A>C variant, or of a new amino acid substitution in the 3'-end of exon 4.
|
16485124 |
2006 |
rs2066845
|
|
|
1.000 |
GeneticVariation |
UNIPROT |
We performed a limited DNA sequence analysis of the CARD15 gene in 89 patients with Crohn's disease (CD), 19 patients with ulcerative colitis (UC), and three patients with indeterminate colitis (IC), who were heterozygous carriers of one of the common CARD15 mutations [c.2104C>T (p.R702W), c.2722G>C (p.G908R), or c.3019_3020insC (p.Leu1007fsX1008)], the c.2462+10A>C variant, or of a new amino acid substitution in the 3'-end of exon 4.
|
16485124 |
2006 |
rs2066844
|
|
|
1.000 |
GeneticVariation |
UNIPROT |
Crohn disease: frequency and nature of CARD15 mutations in Ashkenazi and Sephardi/Oriental Jewish families.
|
15024686 |
2004 |
rs2066845
|
|
|
1.000 |
GeneticVariation |
UNIPROT |
A higher frequency of CARD15 mutations was found in AJ patients from multiplex families with CD from Central (44.0%) versus Eastern (24.0%) Europe, especially for G908R and 1007fs, and in SOJ patients (34.5%) compared with AJ (10.1%) or SOJ (5.4%) controls.
|
15024686 |
2004 |
rs2066844
|
|
|
1.000 |
GeneticVariation |
UNIPROT |
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease.
|
11385576 |
2001 |
rs2066845
|
|
|
1.000 |
GeneticVariation |
UNIPROT |
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease.
|
11385576 |
2001 |
rs2066847
|
|
T |
0.890 |
GeneticVariation |
GWASDB |
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
|
23128233 |
2012 |
rs2066847
|
|
T |
0.890 |
GeneticVariation |
GWASCAT |
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
|
23128233 |
2012 |
rs2066847
|
|
|
0.890 |
GeneticVariation |
GWASCAT |
Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.
|
20570966 |
2010 |
rs2066847
|
|
|
0.890 |
GeneticVariation |
GWASDB |
Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.
|
20570966 |
2010 |
rs2066847
|
|
C |
0.890 |
GeneticVariation |
GWASDB |
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.
|
18587394 |
2008 |
rs2066847
|
|
C |
0.890 |
GeneticVariation |
GWASCAT |
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.
|
18587394 |
2008 |