|
rs6313
|
|
|
0.020 |
GeneticVariation |
BEFREE |
No association was observed between T102C alleles or genotypes and delusions, agitation/aggression, depression, and apathy (<i>p</i> > 0.05).
|
29349076 |
2017 |
|
rs6313
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Thus our study, although at preliminary level, suggests that the presence of T allele of the 102T/C polymorphism in patients with Alzheimer's disease is associated with both increased presence of delusion symptoms and treatment-resistance to second generation antipsychotic drugs.
|
19494443 |
2009 |
|
rs1801028
|
|
|
0.020 |
GeneticVariation |
BEFREE |
When we considered the 887 subjects with the symptomatologic analysis, we observed a significant association of the DRD2 S311C variant with both delusion and disorganization features.
|
10889529 |
2000 |
|
rs1801028
|
|
|
0.020 |
GeneticVariation |
BEFREE |
These data suggest that S311C might be one of the genetic factors for symptomatic dimensions of delusions and hallucinations and might be involved in underlying clinical heterogeneity in schizophrenia and affective disorders.
|
8723039 |
1996 |
|
rs63750577
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A review of the available case reports indicates some phenotypic variability associated with the S170F mutation including different constellations of symptoms such as parkinsonism and delusions.
|
29466804 |
2018 |
|
rs5930
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Regarding LDLR variants, carriers of the A allele of rs11669576 had less anxiety and more aberrant motor behavior, whereas carriers of the A allele of rs5930 had less delusions, less anxiety, more apathy, and more irritability.
|
28099631 |
2017 |
|
rs2032582
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Males with the G/G genotype of MDR1 rs2032582 presented significantly higher levels of delusions (p = 0.02).
|
24918524 |
2014 |
|
rs5905587
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Additionally, we found one haplotype constructed by two SNPs, rs5905587-rs37615860, in MAOB/NDP gene region was significantly associated with delusions in all samples tested (Bonferroni corrected P: 0.048).
|
22414661 |
2012 |
|
rs9875793
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Further support for the hypothesis that rs9875793 is associated with BD in patients displaying 'negative mood delusions' symptom, such as delusions of guilt, was obtained from an European American sample (GAIN/TGEN), which included 1247 BD patients and 1434 controls (P(EA)=0.028, OR=1.27).
|
23010768 |
2012 |
|
rs10883866
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Previous fine mapping of the 10q22-23 locus in schizophrenia identified genome-wide significant association between delusion severity and polymorphisms in intron 1 of NRG3 (rs10883866, rs10748842, and rs6584400).
|
20713722 |
2010 |
|
rs4680
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We genotyped rs4680 in a sample of 467 patients affected by bipolar disorder type I with or without a previous illness episode with psychotic features (DSM-IV criteria: delusions or hallucinations).
|
20122740 |
2010 |
|
rs165599
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The SNP rs165599, which has been mapped to the 3'-UTR region of the COMT gene, was significantly associated with schizophrenia in our family study, and possibly associated with the age of onset, delusion/hallucination symptom dimension, and CPT performance.
|
19369177 |
2009 |
|
rs2153674
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, multivariate regression showed that the rs2153674 genotype accounts for up to 15% of the variance in delusions severity, as assessed by using the Neuropsychiatric Inventory.
|
20009237 |
2009 |
|
rs6265
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The methionine variant of Val66Met brain-derived neurotrophic factor BDNF met and catecholamine-O-methyltransferase (COMT L) is associated with a deficit in attention and aggravation of delusions in schizophrenia.
|
18596619 |
2008 |
|
rs6494223
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A significant association between delusions and the T allele of rs6494223 (P = 0.014, OR = 1.63, CI = 1.22-2.17) was found.
|
18696274 |
2008 |
|
rs759834365
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The methionine variant of Val66Met brain-derived neurotrophic factor BDNF met and catecholamine-O-methyltransferase (COMT L) is associated with a deficit in attention and aggravation of delusions in schizophrenia.
|
18596619 |
2008 |
|
rs1805054
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, the HTR6 T267C polymorphism has been linked to risperidone response for positive symptoms (delusions and hallucinations).
|
15882132 |
2005 |