rs6313
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Associations between suicidal ideation and 5-HTTLPR, STin2 VNTR, 5-HTR2a 1438A/G, and 5-HTR2a 102T/C genotypes were estimated using logistic regression models, and gene-gene interactions were investigated using the generalized multifactor dimensionality reduction method after adjustment for potential covariates, including depression.
|
23973249 |
2014 |
rs6313
|
|
|
0.050 |
GeneticVariation |
BEFREE |
To investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.
|
23157339 |
2013 |
rs6313
|
|
|
0.050 |
GeneticVariation |
BEFREE |
5-HT2A receptor gene polymorphism rs6313 was associated with 5-HT2A receptor binding potential, with the ability of individuals to use environmental support in order to prevent depression, and with sleep improvement after antidepressant treatment with mirtazapine.
|
18801406 |
2008 |
rs6313
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Reports have shown an association of a serotonin-2A receptor (HTR2A) gene T102C polymorphism with AD + P and with depression during AD.
|
17525976 |
2007 |
rs6313
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The aim of this study was to investigate the role of serotonin in depression, searching for association of two serotoninergic polymorphisms (T102C of serotonin receptor 5-HT2A and serotonin transporter linked polymorphic region -5-HTTLPR- of SLC6A4 gene) with depressive symptoms and considering their possible interactions with Apolipoprotein E (ApoE) and between themselves, in a sample of 208 sporadic AD patients and 116 normal controls from Italy.
|
17183148 |
2006 |
rs3125
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, the association of rs3125 with brooding could be replicated across the separate subsamples, and remained significant even when controlling for lifetime depression and the Brief Symptom Inventory depression score.
|
31258491 |
2019 |
rs6311
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Based on previous studies indicating that a single nucleotide polymorphism in the serotonin 2A receptor gene [<i>HTR2A</i> rs6311 guanine (G) vs. adenine (A)] is associated with sensitivity to emotional stimuli and several mental disorders such as depression, we predicted that the polymorphism might be associated with the effect of sharing happiness.
|
29311795 |
2017 |
rs6314
|
|
|
0.010 |
GeneticVariation |
BEFREE |
There was no significant association between rs6314 (C/C versus T carriers) and severity of depression.
|
24968012 |
2014 |
rs75634836
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.
|
23157339 |
2013 |
rs7997012
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The HTR2A-rs7997012 is worthy of further investigation in studies examining factors that are related to depression course and outcome.
|
23537781 |
2013 |