Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE The genotype and allele frequencies for the BDNF gene Val66Met polymorphism did not differ comparing depression groups (total, bipolar disorder or major depression) and control subjects. 14673216

2003

dbSNP: rs759834365
rs759834365
0.100 GeneticVariation BEFREE The genotype and allele frequencies for the BDNF gene Val66Met polymorphism did not differ comparing depression groups (total, bipolar disorder or major depression) and control subjects. 14673216

2003

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE Assuming that BDNF may be implicated in the putative common pathophysiology of depression and anxiety, we analyzed the association of two BDNF gene single nucleotide polymorphisms (SNPs), 132C > T (formerly named C270T) in the noncoding region of exon V and 196G > A (val66met) in the coding region of exon XIIIA, with panic disorder. 15913870

2005

dbSNP: rs759834365
rs759834365
0.100 GeneticVariation BEFREE Assuming that BDNF may be implicated in the putative common pathophysiology of depression and anxiety, we analyzed the association of two BDNF gene single nucleotide polymorphisms (SNPs), 132C > T (formerly named C270T) in the noncoding region of exon V and 196G > A (val66met) in the coding region of exon XIIIA, with panic disorder. 15913870

2005

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE The val66met variant located within the brain-derived neurotrophic factor gene (BDNF) has previously been associated with human neuroticism, a dimension of personality strongly predictive of depressive illness. 16043130

2005

dbSNP: rs759834365
rs759834365
0.100 GeneticVariation BEFREE The val66met variant located within the brain-derived neurotrophic factor gene (BDNF) has previously been associated with human neuroticism, a dimension of personality strongly predictive of depressive illness. 16043130

2005

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE The results suggest that the BDNF Val66Met polymorphism is a relevant risk factor for geriatric depression. 16343697

2006

dbSNP: rs759834365
rs759834365
0.100 GeneticVariation BEFREE The results suggest that the BDNF Val66Met polymorphism is a relevant risk factor for geriatric depression. 16343697

2006

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE The BDNF val66met polymorphism may modify the association between stroke and depression. 17222482

2008

dbSNP: rs759834365
rs759834365
0.100 GeneticVariation BEFREE The BDNF val66met polymorphism may modify the association between stroke and depression. 17222482

2008

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE In 732 Korean community residents ages 65+, diagnosis of depression (Geriatric Mental State Schedule), information on SLEs, and genotypes for 5-HTTLPR and BDNF val66met were ascertained. 17482146

2007

dbSNP: rs759834365
rs759834365
0.100 GeneticVariation BEFREE In 732 Korean community residents ages 65+, diagnosis of depression (Geriatric Mental State Schedule), information on SLEs, and genotypes for 5-HTTLPR and BDNF val66met were ascertained. 17482146

2007

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE Higher order interaction effects involving BDNF Val(66)Met, 5-HTTLPR and childhood adversity may contribute to the etiology of depressive illness. 17579366

2008

dbSNP: rs759834365
rs759834365
0.100 GeneticVariation BEFREE Higher order interaction effects involving BDNF Val(66)Met, 5-HTTLPR and childhood adversity may contribute to the etiology of depressive illness. 17579366

2008

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE The single nucleotide polymorphism (Val66Met), which has been shown to have functional and behavioral effects, was genotyped in 284 depressed participants and 331 controls, showing association with depression (P=0.005). 17632285

2007

dbSNP: rs759834365
rs759834365
0.100 GeneticVariation BEFREE The single nucleotide polymorphism (Val66Met), which has been shown to have functional and behavioral effects, was genotyped in 284 depressed participants and 331 controls, showing association with depression (P=0.005). 17632285

2007

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE I will also review key studies, both human and animal, which have investigated the association of a BDNF single-nucleotide polymorphism (Val66Met) with depression pathogenesis, and detail the number of inconsistencies which also afflict this novel area of BDNF research. 17700574

2007

dbSNP: rs759834365
rs759834365
0.100 GeneticVariation BEFREE I will also review key studies, both human and animal, which have investigated the association of a BDNF single-nucleotide polymorphism (Val66Met) with depression pathogenesis, and detail the number of inconsistencies which also afflict this novel area of BDNF research. 17700574

2007

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE Allelic differences in the brain-derived neurotrophic factor Val66Met polymorphism in late-life depression. 17911362

2007

dbSNP: rs759834365
rs759834365
0.100 GeneticVariation BEFREE Allelic differences in the brain-derived neurotrophic factor Val66Met polymorphism in late-life depression. 17911362

2007

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE Two common functional polymorphisms in catechol-O-methyltransferase (COMT Val158Met) and brain-derived neurotrophic factor (BDNF Val66Met) genes have been implicated in the neurobiology of anxiety and depression. 17941097

2008

dbSNP: rs759834365
rs759834365
0.100 GeneticVariation BEFREE Two common functional polymorphisms in catechol-O-methyltransferase (COMT Val158Met) and brain-derived neurotrophic factor (BDNF Val66Met) genes have been implicated in the neurobiology of anxiety and depression. 17941097

2008

dbSNP: rs893924483
rs893924483
0.020 GeneticVariation BEFREE Two common functional polymorphisms in catechol-O-methyltransferase (COMT Val158Met) and brain-derived neurotrophic factor (BDNF Val66Met) genes have been implicated in the neurobiology of anxiety and depression. 17941097

2008

dbSNP: rs6265
rs6265
0.100 GeneticVariation BEFREE Rumination may be an endophenotype in the pathway from the BDNF Val66Met polymorphism to depression. 17959306

2007

dbSNP: rs759834365
rs759834365
0.100 GeneticVariation BEFREE Rumination may be an endophenotype in the pathway from the BDNF Val66Met polymorphism to depression. 17959306

2007