|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The aim of this study was to assess the genetic contribution of BDNF Val66Met functional polymorphism to AD-related depression.
|
18179845 |
2009 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The aim of this study was to assess the genetic contribution of BDNF Val66Met functional polymorphism to AD-related depression.
|
18179845 |
2009 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The meta-analysis of Val66Met in depression obtained an overall summary OR of 1.06 (95% CI: 0.89-1.26, P = 0.537) comparing MM with VV genotypes and an OR of 0.97 (95% CI: 0.89-1.05, P = 0.403) comparing MV with VV genotypes.
|
18205169 |
2008 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The meta-analysis of Val66Met in depression obtained an overall summary OR of 1.06 (95% CI: 0.89-1.26, P = 0.537) comparing MM with VV genotypes and an OR of 0.97 (95% CI: 0.89-1.05, P = 0.403) comparing MV with VV genotypes.
|
18205169 |
2008 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The brain-derived neurotrophic factor VAL66MET polymorphism and cerebral white matter hyperintensities in late-life depression.
|
18263664 |
2008 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The brain-derived neurotrophic factor VAL66MET polymorphism and cerebral white matter hyperintensities in late-life depression.
|
18263664 |
2008 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
5-HTTLPR and BDNF VAL66MET, functional polymorphisms of the serotonin (5-HT) transporter (SLC6A4) and brain-derived neurotrophic factor (BDNF) gene, impact on two distinct, but interacting signaling systems, which have been related to depression and to the modulation of neurogenesis and plasticity of circuitries of emotion processing.
|
18347599 |
2008 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
5-HTTLPR and BDNF VAL66MET, functional polymorphisms of the serotonin (5-HT) transporter (SLC6A4) and brain-derived neurotrophic factor (BDNF) gene, impact on two distinct, but interacting signaling systems, which have been related to depression and to the modulation of neurogenesis and plasticity of circuitries of emotion processing.
|
18347599 |
2008 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
According to this rationale, we investigated the role of two functional polymorphisms in the genes coding for the serotonin transporter (5-HTTLPR) and the brain-derived neurotrophic factor (BDNF Val66Met), and rTMS response in a group of 36 drug resistant patients affected by mood disorders. rTMS treatment significantly improved depression symptomatology (p<0.0001) and the response was significantly greater in 5-HTTLPR LL homozygotes compared to S allele carriers (p=0.007) and in BDNF Val/Val homozygotes compared to Met allele carriers (p=0.024).
|
18450378 |
2008 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
According to this rationale, we investigated the role of two functional polymorphisms in the genes coding for the serotonin transporter (5-HTTLPR) and the brain-derived neurotrophic factor (BDNF Val66Met), and rTMS response in a group of 36 drug resistant patients affected by mood disorders. rTMS treatment significantly improved depression symptomatology (p<0.0001) and the response was significantly greater in 5-HTTLPR LL homozygotes compared to S allele carriers (p=0.007) and in BDNF Val/Val homozygotes compared to Met allele carriers (p=0.024).
|
18450378 |
2008 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Here, we determined the effects of the BDNF Val66met polymorphism on the five-factor personality dimensions (assessed using the NEO-FFI), trait depression (assessed with the DASS-21) in a cross-sectional cohort of 467 healthy volunteers.
|
18548532 |
2009 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Here, we determined the effects of the BDNF Val66met polymorphism on the five-factor personality dimensions (assessed using the NEO-FFI), trait depression (assessed with the DASS-21) in a cross-sectional cohort of 467 healthy volunteers.
|
18548532 |
2009 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Association between BDNF Val66Met polymorphism and trait depression is mediated via resting EEG alpha band activity.
|
18721847 |
2008 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Association between BDNF Val66Met polymorphism and trait depression is mediated via resting EEG alpha band activity.
|
18721847 |
2008 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In the total sample, the BDNF Val66Met polymorphism was not significantly associated with depression.
|
18852698 |
2010 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In the total sample, the BDNF Val66Met polymorphism was not significantly associated with depression.
|
18852698 |
2010 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Interactions between BDNF Val66Met polymorphism and early life stress predict brain and arousal pathways to syndromal depression and anxiety.
|
19153574 |
2009 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Interactions between BDNF Val66Met polymorphism and early life stress predict brain and arousal pathways to syndromal depression and anxiety.
|
19153574 |
2009 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
However, BDNF rs7103411 and rs6265 similarly predicted worse treatment response over 6 wk in clinical subtypes of depression such as melancholic depression only (rs7103411: TT < CC, p = 0.003; rs6265: GG < AA, p = 0.001).
|
19236730 |
2010 |
|
rs7103411
|
|
|
0.030 |
GeneticVariation |
BEFREE |
However, BDNF rs7103411 and rs6265 similarly predicted worse treatment response over 6 wk in clinical subtypes of depression such as melancholic depression only (rs7103411: TT < CC, p = 0.003; rs6265: GG < AA, p = 0.001).
|
19236730 |
2010 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The BDNF Val66Met polymorphism impacts parahippocampal and amygdala volume in healthy humans: incremental support for a genetic risk factor for depression.
|
19335934 |
2009 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The BDNF Val66Met polymorphism impacts parahippocampal and amygdala volume in healthy humans: incremental support for a genetic risk factor for depression.
|
19335934 |
2009 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The low activity variants of the 5-HTT-linked polymorphic region in the serotonin transporter gene and the Met-allele of a single nucleotide polymorphism (Val66Met) in the gene encoding brain derived neurotrophic factor were independently associated with the presence of stressful life events prior to onset of depression, also when corrected for the effect of age, gender, marital status, personality disorder, neuroticism, and severity of depressive symptoms at the time of interview.
|
19339052 |
2009 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The low activity variants of the 5-HTT-linked polymorphic region in the serotonin transporter gene and the Met-allele of a single nucleotide polymorphism (Val66Met) in the gene encoding brain derived neurotrophic factor were independently associated with the presence of stressful life events prior to onset of depression, also when corrected for the effect of age, gender, marital status, personality disorder, neuroticism, and severity of depressive symptoms at the time of interview.
|
19339052 |
2009 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The aims of the present case-control study were to investigate the possible role of BDNF Val66Met, 5-HTTLPR and -1438 G/A polymorphisms in the development of coronary artery disease (CAD) in patients with and without depression.
|
19885623 |
2009 |