rs780094
|
|
|
0.740 |
GeneticVariation |
BEFREE |
In the Danish MONICA study four gene variants were significantly associated with incident CVD independently of known diabetes status at baseline; SLC2A2 rs11920090 (HR 1.147, 95% CI 1.027-1.283 , P = 0.0154), C2CD4A rs7172432 (1.112, 1.027-1.205 , P = 0.0089), GCKR rs780094 (1.094, 1.007-1.188 , P = 0.0335) and C2CD4B rs11071657 (1.092, 1.007-1.183 , P = 0.0323).
|
23185617 |
2012 |
rs780094
|
|
|
0.740 |
GeneticVariation |
BEFREE |
This study provides the first evidence that GCKR rs780094, a single-nucleotide polymorphism related to diabetes, may be associated with pancreatic cancer risk.
|
22015968 |
2012 |
rs780094
|
|
|
0.740 |
GeneticVariation |
BEFREE |
The intronic single-nucleotide polymorphism (SNP) rs780094 (intron 16) and the missense SNP rs1260326 (P446L) in the GCKR gene are strongly associated with increased circulating triglyceride and C-reactive protein levels and, paradoxically, reductions in diabetes incidence, fasting glucose levels, and insulin resistance.
|
21525158 |
2011 |
rs780094
|
|
|
0.740 |
GeneticVariation |
BEFREE |
Our findings indicate rs780094 has independent associations with multiple metabolic traits as well as incident diabetes, but not incident CHD or stroke.
|
20661421 |
2010 |
rs780092
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Mediation analysis showed that both baseline TG and the 5 year increase in log10 TG were significant mediators in the associations of rs780092 with risk of diabetes.
|
26515422 |
2016 |
rs1260326
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The intronic single-nucleotide polymorphism (SNP) rs780094 (intron 16) and the missense SNP rs1260326 (P446L) in the GCKR gene are strongly associated with increased circulating triglyceride and C-reactive protein levels and, paradoxically, reductions in diabetes incidence, fasting glucose levels, and insulin resistance.
|
21525158 |
2011 |