Source: BEFREE ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2241766
rs2241766
0.030 GeneticVariation BEFREE We measured plasma adiponectin levels and genotyped +45T>G (rs2241766) and +276G>T (rs1501299) in the ADIPOQ gene among 417 incident diabetes cases and 1197 control subjects matched by age, sex, and area. 28407551

2017

dbSNP: rs2241766
rs2241766
0.030 GeneticVariation BEFREE The prevalence of diabetic nephropathy tended to be different according to rs2241766 genotype (p=0.057) and the GG genotype of rs2241766 was associated with diabetic nephropathy [urine albumin/creatinine ratio (UACR) greater than 30 mg/g] after adjusting for age, sex, body mass index, duration of diabetes, HDL-cholesterol, smoking status, and blood pressure (odds ratio=1.96; 95% confidence interval=1.01-3.82, p=0.049). 23260797

2013

dbSNP: rs2241766
rs2241766
0.030 GeneticVariation BEFREE Two common single nucleotide polymorphisms (SNPs) at the adiponectin locus (45T>G and 276G>T) have been reported to be associated with diabetes and cardiovascular diseases. 18191060

2008

dbSNP: rs1501299
rs1501299
0.010 GeneticVariation BEFREE We measured plasma adiponectin levels and genotyped +45T>G (rs2241766) and +276G>T (rs1501299) in the ADIPOQ gene among 417 incident diabetes cases and 1197 control subjects matched by age, sex, and area. 28407551

2017

dbSNP: rs17300539
rs17300539
0.010 GeneticVariation BEFREE The -3971 A/G (rs822396) and -11391 G/A (rs17300539) SNPs' association with T2DM diabetes was mediated through obesity (where the association with type 2 diabetes was lost after adjusting for BMI). 24055485

2013

dbSNP: rs822396
rs822396
0.010 GeneticVariation BEFREE The -3971 A/G (rs822396) and -11391 G/A (rs17300539) SNPs' association with T2DM diabetes was mediated through obesity (where the association with type 2 diabetes was lost after adjusting for BMI). 24055485

2013

dbSNP: rs266729
rs266729
0.010 GeneticVariation BEFREE Our aim was to examine the association between the rs266729 promoter gene variant (-11377C > G) and plasma markers of oxidative stress in diabetes subjects. 19324915

2009

dbSNP: rs17366743
rs17366743
0.010 GeneticVariation BEFREE A nonsynonymous coding SNP (rs17366743, Y111H) was confirmed to be associated with diabetes incidence (HR 1.94 [95% CI 1.16-3.25] for the minor C allele; P(n) = 0.01) and with higher mean fasting glucose over 28 years of follow-up (P(n) = 0.0004; P(e) = 0.004). 18776141

2008

dbSNP: rs185847354
rs185847354
0.010 GeneticVariation BEFREE Genetic investigation has revealed that 2 polymorphisms (I164T and G276T) are related to adiponectin concentration and diabetes. 15123570

2004

dbSNP: rs199646033
rs199646033
0.010 GeneticVariation BEFREE Among human adiponectin mutations, G84R and G90S mutants, which are associated with diabetes and hypoadiponectinemia, did not form HMW multimers. 12878598

2003

dbSNP: rs62625753
rs62625753
0.010 GeneticVariation BEFREE Among human adiponectin mutations, G84R and G90S mutants, which are associated with diabetes and hypoadiponectinemia, did not form HMW multimers. 12878598

2003