Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2070600
rs2070600
0.070 GeneticVariation BEFREE We found that Gly82Ser in RAGE showed significant association with DR. More studies with larger sample sizes that control for important risk factors, such as duration of diabetes, are needed to validate our findings. 27684793

2016

dbSNP: rs2070600
rs2070600
0.070 GeneticVariation BEFREE The findings suggest that the G82S polymorphism in the RAGE gene is associated with DR risk, and G82S was associated with circulating levels of sRAGE. 24303504

2013

dbSNP: rs2070600
rs2070600
0.070 GeneticVariation BEFREE Otherwise, the RAGE Gly82Ser polymorphism might be considered a significant risk for DR in Asian populations. 22354095

2012

dbSNP: rs2070600
rs2070600
0.070 GeneticVariation BEFREE Z+2 allele of ALR2, 13-repeat genotype of iNOS, 15-repeat genotype of TNF-β, genes were associated with susceptibility to DR. Gly82Ser polymorphisms of the RAGE gene were not associated with DR in the present study. 21067489

2010

dbSNP: rs2070600
rs2070600
0.070 GeneticVariation BEFREE Among the nine loci (15 polymorphisms) screened, SNP rs2070600 (G82S) in the RAGE gene, showed significant association with DR (allelic P = 0.016, dominant model P = 0.012), compared to DNR. 21067572

2010

dbSNP: rs2070600
rs2070600
0.070 GeneticVariation BEFREE This study confirms significant association of one polymorphism only (rs2070600 in RAGE) with DR in an Indian population which had T2DM. 21067572

2010

dbSNP: rs2070600
rs2070600
0.070 GeneticVariation BEFREE G82S polymorphism in the RAGE gene is associated with DR and G-A haplotype containing 1704G and 82S allele might be a genetic marker of DR in Chinese T2DM patients. 19542745

2009

dbSNP: rs2070600
rs2070600
0.070 GeneticVariation BEFREE Association of Gly82Ser polymorphism in the RAGE gene with diabetic retinopathy in type II diabetic Asian Indian patients. 12477623

2003

dbSNP: rs1800625
rs1800625
0.020 GeneticVariation BEFREE The rs1800625 SNP may be associated with the development of diabetic retinopathy, cancer, and lupus but may be protective against cardiovascular risk. 30863465

2019

dbSNP: rs1800625
rs1800625
0.020 GeneticVariation BEFREE A meta-analysis was performed to assess the associations of the receptor for advanced glycation end products (RAGE) gene polymorphisms [Gly82Ser (rs2070600), 1704G/T (rs184003), 429T/C (rs1800625)] with type 2 diabetes mellitus (T2DM), diabetic retinopathy (DR) and diabetic nephropathy (DN). 22475522

2012