Gene: AKR1B1 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs759853
rs759853
AKR1B1
0.040 GeneticVariation BEFREE CONCLUSIONS ALR2 rs759853 and SDH rs2055858 polymorphisms were respectively associated with a higher and lower risk of diabetic retinopathy. 31539366

2019
dbSNP: rs759853
rs759853
AKR1B1
0.040 GeneticVariation BEFREE AKR1B1 polymorphism rs759853 may inhibit the occurrence of DR in patients with type 1 DM. 30201105

2018
dbSNP: rs759853
rs759853
AKR1B1
0.040 GeneticVariation BEFREE Present study aimed to investigate the association of aldose reductase (AKR1B1) gene polymorphism (-106C>T; rs759853) with diabetic retinopathy (DR) in type 2 diabetes mellitus (T2DM) patients from north India. 27640118

2016
dbSNP: rs759853
rs759853
AKR1B1
0.040 GeneticVariation BEFREE The T allele of the AKR1B1 promoter rs759853 variant is also significantly protective against diabetic retinopathy in type 1 diabetes (0.5 [0.35-0.71], P = 1.00 x 10(-4)), regardless of ethnicity. 19587357

2009
dbSNP: rs200903070
rs200903070
AKR1B1
0.010 GeneticVariation BEFREE We investigated the relationship between diabetic retinopathy (DR) and three polymorphisms, C(-106)T in the aldose reductase (ALR2) gene, 4G/5G in the plasminogen activator inhibitor-1 (PAI-1) gene and C677T in the methylenetetrahydrofolate reductase (MTHFR) gene, in 210 Euro-Brazilian type 2 diabetic patients. 12951282

2003