rs2010963
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We found that the VEGF rs2010963 CG + GG genotypes had a significantly increased risk of hand-foot syndrome, and the ABCB1 rs1045642 CT + TT genotypes had an increased risk of high blood pressure.
|
26830973 |
2016 |
rs3025039
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Genotype CT of rs3025039, TT of rs2305948, and AA of rs1873077 were associated with a reduced risk of CHD when smoking, alcohol intake and diabetes were considered, while homozygote GG of rs1570360 might elevate the susceptibility to CHD (all P < 0.05) for patients who were addicted to smoking or those with hypertension.
|
27175642 |
2016 |
rs1222213359
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The A allele of the -2578C>A polymorphism and haplotypes of the -2578C>A and -1154G>A polymorphisms in the promoter region of the VEGF gene might be protective against the development of hypertension in Koreans.
|
26154735 |
2015 |
rs2010963
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Also, adjusted ORs in the presence of normolipidemia and the absence of history of hypertension for the risk of CAD in the either ACE(rs4646994) D allele or VGEF(rs2010963)-G alleles were 2.08 (p=0.004) and 1.75 (p=0.024), respectively.
|
24505095 |
2015 |
rs3025039
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In this retrospective study, the rs3025039 polymorphism was significantly associated with time to treatment failure and hypertension in patients treated with bevacizumab-based chemotherapy.
|
25617075 |
2015 |
rs1222213359
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We examined whether vascular endothelial growth factor (VEGF) polymorphisms (C-2578A, G-1154A and G-634C) are associated with hypertension, response to antihypertensive therapy and nitric oxide (NO) formation.
|
22189703 |
2013 |
rs1570360
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotype CT of rs3025039, TT of rs2305948, and AA of rs1873077 were associated with a reduced risk of CHD when smoking, alcohol intake and diabetes were considered, while homozygote GG of rs1570360 might elevate the susceptibility to CHD (all P < 0.05) for patients who were addicted to smoking or those with hypertension.
|
27175642 |
2016 |
rs699947
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggest that rs699947 (T>C) on KDR are associated with susceptibility to CHD under the dominant model before (OR=1.35, 95% CI: 1.05-1.73, P=0.019) and after (OR=1.33, 95% CI: 1.01-1.76, P=0.044), allowing for clinical characteristics (e.g., BMI, smoking, alcohol consumption, diabetes, and hypertension). rs2305948 (G>A) and rs1870377 (A>T) on VEGF were also found to be associated with risk of CHD under the recessive model after adjustment with multivariate regression analyses (OR=1.21, 95% CI: 1.02-1.43, P=0.029; OR=2.54, 95% CI: 1.13-5.75, P=0.025); OR=2.83, 95% CI: 1.47-5.46, P=0.002, respectively).
|
26726843 |
2016 |