Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2304205
rs2304205
IRF3 ; BCL2L12
0.010 GeneticVariation BEFREE We analyzed two gene variants in IRF3 (rs7251 and rs2304205) on the clinical outcome of 249 AML patients submitted to HLA-identical sibling allo-SCT. 23542224

2013
dbSNP: rs11554137
rs11554137
IDH1
0.010 GeneticVariation BEFREE IDH1 SNP rs11554137 was recently reported in association with poor prognosis in normal karyotype adult acute myeloid leukemia (AML). 21873548

2011
dbSNP: rs1045642
rs1045642
ABCB1
0.010 GeneticVariation BEFREE The aim of this study was to investigate the potential involvement of the ABCB1 gene exon 26 3435C>T single nucleotide polymorphism (SNP) in the genetic susceptibility to AML and regulation of P-gp expression and activity in AML cells. 17038891

2006
dbSNP: rs1057520026
rs1057520026
FLT3
0.010 GeneticVariation BEFREE FLT3 K663Q is a novel AML-associated oncogenic kinase: Determination of biochemical properties and sensitivity to Sunitinib (SU11248). 16990784

2006
dbSNP: rs1217691063
rs1217691063
MTHFR
0.010 GeneticVariation BEFREE In this study we describe the genotyping of the MTHFR C677T polymorphism by melting curve analysis with the LightCycler in a case-controlled study of patients with acute lymphocytic leukemia (ALL), myelogenous leukemia (AML), and chronic myelogenous leukemia (CML), and assess the effect of this common polymorphism on the leukemia risk in adult patients in Turkey. 15068389

2003