|
rs549908
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We therefore investigated for the influence of interleukin-18 (-1297T/C, -607A/C, -137G/C; + 105A/C) polymorphisms on genetic susceptibility and clinical expression of the disease in Indian systemic lupus erythematosus patients.
|
30857465 |
2019 |
|
rs187238
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The third SNP, rs187238, was not significantly associated with SLE in any of the populations examined.
|
26026656 |
2015 |
|
rs1946518
|
|
|
0.030 |
GeneticVariation |
BEFREE |
In summary, this study identified a significant association between SLE and two SNPs within the IL-18 gene promoter region (rs360719 and rs1946518</span>) in a European population, but not in populations of Asian origin.
|
26026656 |
2015 |
|
rs360719
|
|
|
0.030 |
GeneticVariation |
BEFREE |
In summary, this study identified a significant association between SLE and two SNPs within the IL-18 gene promoter region (rs360719 and rs1946518) in a European population, but not in populations of Asian origin.
|
26026656 |
2015 |
|
rs187238
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The aim of this study was to determine whether the three functional interleukin-18 (IL-18) promoter -607 C/A (rs1946518), -137 G/C (rs187238), and -1297 C/T (rs360719) polymorphisms confer susceptibility to systemic lupus erythematosus (SLE) in ethnically different populations.
|
23238919 |
2013 |
|
rs1946518
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The aim of this study was to determine whether the three functional interleukin-18 (IL-18) promoter -607 C/A (rs1946518), -137 G/C (rs187238), and -1297 C/T (rs360719) polymorphisms confer susceptibility to systemic lupus erythematosus (SLE) in ethnically different populations.
|
23238919 |
2013 |
|
rs360719
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The aim of this study was to determine whether the three functional interleukin-18 (IL-18) promoter -607 C/A (rs1946518), -137 G/C (rs187238), and -1297 C/T (rs360719) polymorphisms confer susceptibility to systemic lupus erythematosus (SLE) in ethnically different populations.
|
23238919 |
2013 |
|
rs187238
|
|
|
0.030 |
GeneticVariation |
BEFREE |
For the relationship between IL-18 rs187238 polymorphism and RA or SLE, there was no significant association detected in all genetic models, even in Chinese population.
|
23153245 |
2012 |
|
rs1946518
|
|
|
0.030 |
GeneticVariation |
BEFREE |
For the relationship of IL-18 rs1946518 polymorphism with RA (additive model: OR=0.752, 95%CI=0.562-1.006; dominant model: OR=0.730, 95%CI =0.479-1.113; recessive model: OR=0.537, 95%CI=0.271-1.064) and SLE (additive model: OR=0.684, 95%CI=0.455-1.028; dominant model: OR=0.645, 95%CI=0.368-1.130; recessive model: OR=0.672, 95%CI =0.447-1.010), no significant association with RA and SLE risk can be found under all genetic models in Asian populations.
|
23153245 |
2012 |
|
rs360719
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our large well-powered study (98% to detect odds ratio = 1.5, with respect to rs360719) showed that no individual SNP or haplotype was associated with SLE in any of the cohorts studied.
|
21149337 |
2011 |
|
rs549908
|
|
|
0.030 |
GeneticVariation |
BEFREE |
An IL-18 genetic A/C polymorphism at coding position 105 (rs549908) has been linked with asthma, rheumatoid, and systemic lupus erythematosus.
|
19288449 |
2009 |
|
rs549908
|
|
|
0.030 |
GeneticVariation |
BEFREE |
There were no significant differences in the distribution of IL-18 105 A>C polymorphic variants in SLE patients and controls.
|
19387647 |
2009 |