|
rs12075
|
|
|
0.010 |
GeneticVariation |
BEFREE |
FYB carriage (deduced from DARC G125A) was not associated with the risk of malaria per se but it protected against severe falciparum malaria (P = 0.03), and hospitalization (P = 0.006) due to falciparum malaria.
|
31551092 |
2019 |
|
rs3745274
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A total of 418 patients with HIV-1 mono-infection, HIV-1 and Tuberculosis coinfection and symptomatic P. falciparum malaria were genotyped for the CYP2B6 c.516G>T SNP using Restriction Fragment Length Polymorphism (RFLP).
|
30818046 |
2019 |
|
rs776022790
|
|
|
0.010 |
GeneticVariation |
BEFREE |
FYB carriage (deduced from DARC G125A) was not associated with the risk of malaria per se but it protected against severe falciparum malaria (P = 0.03), and hospitalization (P = 0.006) due to falciparum malaria.
|
31551092 |
2019 |
|
rs1884444
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Since variation within the coding region of IL-23R may influence the pathogenesis of SMA, the association between IL-23R rs1884444 (G/T), rs7530511 (C/T), and SMA (Hb < 6.0 g/dL) was examined in children (n = 369, aged 6-36 months) with P. falciparum malaria in a holoendemic P. falciparum transmission area.
|
28427357 |
2017 |
|
rs5030868
|
|
|
0.010 |
GeneticVariation |
BEFREE |
G6PD c.563C>T was observed in four of 110 patients with falciparum malaria and in two of 100 healthy donors.
|
29065882 |
2017 |
|
rs7530511
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Since variation within the coding region of IL-23R may influence the pathogenesis of SMA, the association between IL-23R rs1884444 (G/T), rs7530511 (C/T), and SMA (Hb < 6.0 g/dL) was examined in children (n = 369, aged 6-36 months) with P. falciparum malaria in a holoendemic P. falciparum transmission area.
|
28427357 |
2017 |
|
rs8177374
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the present study, we investigated the association of TIRAP (S180L) polymorphism with susceptibility/resistance to severe P. falciparum malaria in a cohort of adult patients from India.
|
27166096 |
2016 |
|
rs12212067
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The FOXO3A variant rs12212067T>G is associated with increased inflammatory responses to Plasmodium falciparum malaria, indicating a role of the FOXO3-dependent pathway in malaria.
|
25421486 |
2015 |
|
rs867186
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A total of 707 Thai patients with P. falciparum malaria (341 with severe malaria and 336 with mild malaria) were genotyped for rs867186.
|
24635948 |
2014 |
|
rs3091307
|
|
|
0.010 |
GeneticVariation |
BEFREE |
As such, the association between the IL-13 variants -7402 T/G (rs7719175) and -4729G/A (rs3091307) and susceptibility to SMA was determined in children (n = 387) presenting with clinical symptoms of falciparum malaria and resident in a holoendemic transmission region in western Kenya.
|
23521898 |
2013 |
|
rs34383331
|
|
|
0.010 |
GeneticVariation |
BEFREE |
It is the first study, which shows that the allele A (rs34383331T > A) in ncRNA is significantly associated with increased risk to P. falciparum malaria [severe: OR = 2.08, p = 0.002 and mild: OR = 2.09, P = 0.005].
|
24066864 |
2013 |
|
rs7719175
|
|
|
0.010 |
GeneticVariation |
BEFREE |
As such, the association between the IL-13 variants -7402 T/G (rs7719175) and -4729G/A (rs3091307) and susceptibility to SMA was determined in children (n = 387) presenting with clinical symptoms of falciparum malaria and resident in a holoendemic transmission region in western Kenya.
|
23521898 |
2013 |
|
rs3212227
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Since the role of IL12B variants in conditioning susceptibility to SMA remains largely unexplored, the association between a single nucleotide polymorphism (1188A→C, rs3212227), SMA (Hb<6.0 g/dL), circulating IL-12p40/p70 levels, and longitudinal clinical outcomes in Kenyan children (n = 756) residing in a holoendemic falciparum malaria transmission area were investigated.
|
21819616 |
2011 |
|
rs7246355
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To extend these investigations, the relationships between a novel SCGF promoter variant (-539C/T, rs7246355), SMA (hemoglobin [Hb] < 6.0 g/dl), and reduced erythropoietic responses (reticulocyte production index [RPI], <2.0) were investigated with Kenyan children (n = 486) with falciparum malaria from western Kenya.
|
19884328 |
2010 |
|
rs17860508
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To examine whether the CTCTAA allele is associated with susceptibility to cerebral malaria in Asian populations, 303 Thai patients with Plasmodium falciparum malaria (109 cerebral malaria and 194 mild malaria patients) were genotyped for rs17860508 by PCR-direct sequencing.
|
20003322 |
2009 |
|
rs2234711
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To examine possible association of the IFN-gamma receptor 1 (IFNGR1) polymorphisms with cerebral malaria, 312 adult patients with Plasmodium falciparum malaria (203 mild and 109 cerebral malaria patients) living in northwest Thailand were genotyped for six single nucleotide polymorphisms (SNPs) including -56T/C (rs2234711) and a microsatellite marker in IFNGR1.
|
19712753 |
2009 |
|
rs76980269
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We have analyzed two single nucleotide polymorphisms (SNPs) of nNOS gene (-84G-->A and 276C-->T), responsible for decreased basal transcriptional activity, in 200 patients with mild Plasmodium falciparum malaria and 170 patients with cerebral malaria.
|
19540363 |
2009 |
|
rs1799724
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We examined a possible association of three single nucleotide polymorphisms (SNPs) of the tumor necrosis factor alpha (TNF) promoter -1031T>C (rs1799964), -863C>A (rs1800630), and -857C>T (rs1799724) with severe malaria in 466 adult patients having Plasmodium falciparum malaria in northwest Thailand.
|
17493155 |
2007 |
|
rs1799964
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We examined a possible association of three single nucleotide polymorphisms (SNPs) of the tumor necrosis factor alpha (TNF) promoter -1031T>C (rs1799964), -863C>A (rs1800630), and -857C>T (rs1799724) with severe malaria in 466 adult patients having Plasmodium falciparum malaria in northwest Thailand.
|
17493155 |
2007 |