rs5770917
|
|
|
0.840 |
GeneticVariation |
BEFREE |
The HLA-DQB1*06:02 allele across all ethnic groups and the rs5770917 variation between CPT1B and CHKB genes in Japanese and Koreans are common genetic susceptibility factors for narcolepsy.
|
24571861 |
2014 |
rs5770917
|
|
|
0.840 |
GeneticVariation |
BEFREE |
The study extends on the observation of a strong multiethnic association of polymorphisms in the TCRA and P2RY11 with narcolepsy, but does not confirm the association of CPT1B/CHKB (rs5770917) in the Chinese population.
|
22177342 |
2012 |
rs5770917
|
|
|
0.840 |
GeneticVariation |
BEFREE |
Stepwise multiple regression analysis revealed that the risk allele (C) for SNP rs5770917 was significantly associated with decreased CPT1B mRNA expression (P = 1.0 × 10(-9)), and the CPT1B expression was higher in the narcolepsy patients than in the controls (P = 0.005).
|
21358852 |
2011 |
rs5770917
|
|
C |
0.840 |
GeneticVariation |
GWASDB |
We conducted a genome-wide association study using 500K SNP microarrays in 222 Japanese individuals with narcolepsy and 389 Japanese controls, with replication of top hits in 159 Japanese individuals with narcolepsy and 190 Japanese controls, followed by the testing of 424 Koreans, 785 individuals of European descent and 184 African Americans. rs5770917, a SNP located between CPT1B and CHKB, was associated with narcolepsy in Japanese (rs5770917[C], odds ratio (OR) = 1.79, combined P = 4.4 x 10(-7)) and other ancestry groups (OR = 1.40, P = 0.02).
|
18820697 |
2008 |
rs5770917
|
|
|
0.840 |
GeneticVariation |
BEFREE |
We conducted a genome-wide association study using 500K SNP microarrays in 222 Japanese individuals with narcolepsy and 389 Japanese controls, with replication of top hits in 159 Japanese individuals with narcolepsy and 190 Japanese controls, followed by the testing of 424 Koreans, 785 individuals of European descent and 184 African Americans. rs5770917, a SNP located between CPT1B and CHKB, was associated with narcolepsy in Japanese (rs5770917[C], odds ratio (OR) = 1.79, combined P = 4.4 x 10(-7)) and other ancestry groups (OR = 1.40, P = 0.02).
|
18820697 |
2008 |
rs5770917
|
|
C |
0.840 |
GeneticVariation |
GWASCAT |
We conducted a genome-wide association study using 500K SNP microarrays in 222 Japanese individuals with narcolepsy and 389 Japanese controls, with replication of top hits in 159 Japanese individuals with narcolepsy and 190 Japanese controls, followed by the testing of 424 Koreans, 785 individuals of European descent and 184 African Americans. rs5770917, a SNP located between CPT1B and CHKB, was associated with narcolepsy in Japanese (rs5770917[C], odds ratio (OR) = 1.79, combined P = 4.4 x 10(-7)) and other ancestry groups (OR = 1.40, P = 0.02).
|
18820697 |
2008 |
rs1154155
|
|
C |
0.810 |
GeneticVariation |
GWASCAT |
A polymorphism in CCR1/CCR3 is associated with narcolepsy.
|
25986216 |
2015 |
rs1154155
|
|
G |
0.810 |
GeneticVariation |
GWASCAT |
ImmunoChip study implicates antigen presentation to T cells in narcolepsy.
|
23459209 |
2013 |
rs1154155
|
|
G |
0.810 |
GeneticVariation |
GWASDB |
Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic.
|
24204295 |
2013 |
rs1154155
|
|
G |
0.810 |
GeneticVariation |
GWASCAT |
Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic.
|
24204295 |
2013 |
rs1154155
|
|
G |
0.810 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy.
|
20711174 |
2010 |
rs1154155
|
|
G |
0.810 |
GeneticVariation |
GWASCAT |
Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy.
|
20711174 |
2010 |
rs1154155
|
|
C |
0.810 |
GeneticVariation |
GWASCAT |
Using genome-wide association (GWA) in Caucasians with replication in three ethnic groups, we found association between narcolepsy and polymorphisms in the TRA@ (T-cell receptor alpha) locus, with highest significance at rs1154155 (average allelic odds ratio 1.69, genotypic odds ratios 1.94 and 2.55, P < 10(-21), 1,830 cases, 2,164 controls).
|
19412176 |
2009 |
rs1154155
|
|
|
0.810 |
GeneticVariation |
BEFREE |
Using genome-wide association (GWA) in Caucasians with replication in three ethnic groups, we found association between narcolepsy and polymorphisms in the TRA@ (T-cell receptor alpha) locus, with highest significance at rs1154155 (average allelic odds ratio 1.69, genotypic odds ratios 1.94 and 2.55, P < 10(-21), 1,830 cases, 2,164 controls).
|
19412176 |
2009 |
rs1154155
|
|
C |
0.810 |
GeneticVariation |
GWASDB |
Using genome-wide association (GWA) in Caucasians with replication in three ethnic groups, we found association between narcolepsy and polymorphisms in the TRA@ (T-cell receptor alpha) locus, with highest significance at rs1154155 (average allelic odds ratio 1.69, genotypic odds ratios 1.94 and 2.55, P < 10(-21), 1,830 cases, 2,164 controls).
|
19412176 |
2009 |
rs10995245
|
|
A |
0.800 |
GeneticVariation |
GWASCAT |
Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic.
|
24204295 |
2013 |
rs10995245
|
|
A |
0.800 |
GeneticVariation |
GWASDB |
Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic.
|
24204295 |
2013 |
rs10995245
|
|
A |
0.800 |
GeneticVariation |
GWASCAT |
ImmunoChip study implicates antigen presentation to T cells in narcolepsy.
|
23459209 |
2013 |
rs1551570
|
|
|
0.800 |
GeneticVariation |
GWASCAT |
Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic.
|
24204295 |
2013 |
rs1551570
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic.
|
24204295 |
2013 |
rs2834188
|
|
|
0.800 |
GeneticVariation |
GWASCAT |
Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic.
|
24204295 |
2013 |
rs2834188
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic.
|
24204295 |
2013 |
rs2854536
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic.
|
24204295 |
2013 |
rs2854536
|
|
|
0.800 |
GeneticVariation |
GWASCAT |
Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic.
|
24204295 |
2013 |
rs2858884
|
|
A |
0.800 |
GeneticVariation |
GWASCAT |
Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy.
|
20711174 |
2010 |