Gene: PTPN11 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121918464
rs121918464
PTPN11
0.010 GeneticVariation BEFREE PTPN11 mutations E76K and G503V did not coexist in the same neoplasm. 31277422

2019
dbSNP: rs397507546
rs397507546
PTPN11
0.010 GeneticVariation BEFREE PTPN11 mutations E76K and G503V did not coexist in the same neoplasm. 31277422

2019
dbSNP: rs121918461
rs121918461
PTPN11
0.010 GeneticVariation BEFREE Consistently, in vivo experiments also showed that the tumour sizes and weights were increased significantly in the SHP2 D61G-MB231 group (p < 0.001) in association with tumour metastasis. 26673822

2016
dbSNP: rs886039463
rs886039463
PTPN11
0.010 GeneticVariation BEFREE Furthermore, NIH3T3 cells transformed by T507K SHP-2 showed anchorage-independent growth and developed tumors in nude mice. 18223690

2008