Gene: SDHB ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1131691049
rs1131691049
SDHB
A 0.700 CausalMutation CLINVAR

dbSNP: rs1131691054
rs1131691054
SDHB
A 0.700 GeneticVariation CLINVAR

dbSNP: rs1228560456
rs1228560456
SDHB
A 0.700 GeneticVariation CLINVAR Crystal structure of mitochondrial respiratory membrane protein complex II. 15989954

2005
dbSNP: rs1278834014
rs1278834014
SDHB
A 0.700 GeneticVariation CLINVAR High frequency of SDHB germline mutations in patients with malignant catecholamine-producing paragangliomas: implications for genetic testing. 16912137

2006
dbSNP: rs1278834014
rs1278834014
SDHB
A 0.700 GeneticVariation CLINVAR 15 YEARS OF PARAGANGLIOMA: Clinical manifestations of paraganglioma syndromes types 1-5. 26273102

2015
dbSNP: rs138996609
rs138996609
SDHB
A 0.700 CausalMutation CLINVAR Relevance of germline mutation screening in both familial and sporadic head and neck paraganglioma for early diagnosis and clinical management. 20208144

2010
dbSNP: rs138996609
rs138996609
SDHB
A 0.700 CausalMutation CLINVAR Chromosomal changes in sporadic and familial head and neck paragangliomas. 19393419

2009
dbSNP: rs138996609
rs138996609
SDHB
A 0.700 CausalMutation CLINVAR Clinical presentation and penetrance of pheochromocytoma/paraganglioma syndromes. 16317055

2006
dbSNP: rs138996609
rs138996609
SDHB
A 0.700 CausalMutation CLINVAR Mutations in the SDHB gene are associated with extra-adrenal and/or malignant phaeochromocytomas. 14500403

2003
dbSNP: rs138996609
rs138996609
SDHB
A 0.700 CausalMutation CLINVAR Missense mutations in the human SDHB gene increase protein degradation without altering intrinsic enzymatic function. 22835832

2012
dbSNP: rs138996609
rs138996609
SDHB
A 0.700 CausalMutation CLINVAR A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas. 16103922

2005
dbSNP: rs138996609
rs138996609
SDHB
A 0.700 CausalMutation CLINVAR Clinical predictors for germline mutations in head and neck paraganglioma patients: cost reduction strategy in genetic diagnostic process as fall-out. 19351833

2009
dbSNP: rs138996609
rs138996609
SDHB
A 0.700 CausalMutation CLINVAR Succinate dehydrogenase B gene mutations predict survival in patients with malignant pheochromocytomas or paragangliomas. 17652212

2007
dbSNP: rs138996609
rs138996609
SDHB
A 0.700 CausalMutation CLINVAR The succinate dehydrogenase genetic testing in a large prospective series of patients with paragangliomas. 19454582

2009
dbSNP: rs1553179359
rs1553179359
SDHB
A 0.700 CausalMutation CLINVAR Clinical predictors for germline mutations in head and neck paraganglioma patients: cost reduction strategy in genetic diagnostic process as fall-out. 19351833

2009
dbSNP: rs200245469
rs200245469
SDHB
A 0.700 GeneticVariation CLINVAR The succinate dehydrogenase genetic testing in a large prospective series of patients with paragangliomas. 19454582

2009
dbSNP: rs200245469
rs200245469
SDHB
A 0.700 GeneticVariation CLINVAR Novel SDHB and TMEM127 Mutations in Patients with Pheochromocytoma/Paraganglioma Syndrome. 26960314

2016
dbSNP: rs200245469
rs200245469
SDHB
A 0.700 GeneticVariation CLINVAR Clinicopathological study of SDHB mutation-related pheochromocytoma and sympathetic paraganglioma. 24659481

2014
dbSNP: rs200245469
rs200245469
SDHB
A 0.700 GeneticVariation CLINVAR SDH mutations in tumorigenesis and inherited endocrine tumours: lesson from the phaeochromocytoma-paraganglioma syndromes. 19522823

2009
dbSNP: rs200245469
rs200245469
SDHB
A 0.700 GeneticVariation CLINVAR Tumor risks and genotype-phenotype-proteotype analysis in 358 patients with germline mutations in SDHB and SDHD. 19802898

2010
dbSNP: rs200245469
rs200245469
SDHB
A 0.700 GeneticVariation CLINVAR Clinical predictors for germline mutations in head and neck paraganglioma patients: cost reduction strategy in genetic diagnostic process as fall-out. 19351833

2009
dbSNP: rs267607032
rs267607032
SDHB
A 0.700 GeneticVariation CLINVAR Compound heterozygous mutation with a novel splice donor region DNA sequence variant in the succinate dehydrogenase subunit B gene in malignant paraganglioma. 19927285

2010
dbSNP: rs267607032
rs267607032
SDHB
A 0.700 GeneticVariation CLINVAR Early presentation of familial paraganglioma with SDHB mutation in a 13 year old child and its mother. 20583550

2010
dbSNP: rs267607032
rs267607032
SDHB
A 0.700 GeneticVariation CLINVAR Are these compound heterozygous mutations of SDHB really mutations? 20213850

2010
dbSNP: rs267607032
rs267607032
SDHB
A 0.700 GeneticVariation CLINVAR Paraganglioma, neuroblastoma, and a SDHB mutation: Resolution of a 30-year-old mystery. 20503330

2010