Gene: SDHC ×
Source: CLINVAR ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1057517818
rs1057517818
SDHC
C 0.700 GeneticVariation CLINVAR

dbSNP: rs1131691062
rs1131691062
SDHC
G 0.700 GeneticVariation CLINVAR The succinate dehydrogenase genetic testing in a large prospective series of patients with paragangliomas. 19454582

2009
dbSNP: rs1553265817
rs1553265817
SDHC
C 0.700 CausalMutation CLINVAR

dbSNP: rs201286421
rs201286421
SDHC
T 0.700 CausalMutation CLINVAR Identification of eight novel SDHB, SDHC, SDHD germline variants in Danish pheochromocytoma/paraganglioma patients. 27279923

2016
dbSNP: rs201286421
rs201286421
SDHC
T 0.700 CausalMutation CLINVAR Long-delayed localization of a cardiac functional paraganglioma with SDHC mutation. 22868853

2012
dbSNP: rs201286421
rs201286421
SDHC
T 0.700 CausalMutation CLINVAR Clinical and molecular genetics of patients with the Carney-Stratakis syndrome and germline mutations of the genes coding for the succinate dehydrogenase subunits SDHB, SDHC, and SDHD. 17667967

2008
dbSNP: rs201286421
rs201286421
SDHC
T 0.700 CausalMutation CLINVAR Exploring the association of succinate dehydrogenase complex mutations with lymphoid malignancies. 24781345

2014
dbSNP: rs201286421
rs201286421
SDHC
T 0.700 CausalMutation CLINVAR Polymyalgia rheumatica and vagal paraganglioma. 28412079

2017
dbSNP: rs201286421
rs201286421
SDHC
T 0.700 CausalMutation CLINVAR Secondary variants in individuals undergoing exome sequencing: screening of 572 individuals identifies high-penetrance mutations in cancer-susceptibility genes. 22703879

2012
dbSNP: rs201286421
rs201286421
SDHC
T 0.700 CausalMutation CLINVAR Synchronous carotid body and thoracic paraganglioma associated with a germline SDHC mutation. 21106325

2011
dbSNP: rs201286421
rs201286421
SDHC
T 0.700 CausalMutation CLINVAR The clinical phenotype of SDHC-associated hereditary paraganglioma syndrome (PGL3). 24758179

2014
dbSNP: rs201286421
rs201286421
SDHC
T 0.700 CausalMutation CLINVAR The succinate dehydrogenase genetic testing in a large prospective series of patients with paragangliomas. 19454582

2009
dbSNP: rs587776653
rs587776653
SDHC
C 0.700 CausalMutation CLINVAR

dbSNP: rs587776653
rs587776653
SDHC
T 0.700 CausalMutation CLINVAR Predictors and prevalence of paraganglioma syndrome associated with mutations of the SDHC gene. 16249420

2005
dbSNP: rs587776653
rs587776653
SDHC
T 0.700 CausalMutation CLINVAR Autosomal dominant malignant and catecholamine-producing paraganglioma caused by a splice donor site mutation in SDHC. 12658451

2003
dbSNP: rs587778661
rs587778661
SDHC
T 0.700 GeneticVariation CLINVAR Germline variation in cancer-susceptibility genes in a healthy, ancestrally diverse cohort: implications for individual genome sequencing. 24728327

2014
dbSNP: rs587778661
rs587778661
SDHC
T 0.700 GeneticVariation CLINVAR Yeast model for evaluating the pathogenic significance of SDHB, SDHC and SDHD mutations in PHEO-PGL syndrome. 23175444

2013
dbSNP: rs587778661
rs587778661
SDHC
T 0.700 GeneticVariation CLINVAR Clinical predictors for germline mutations in head and neck paraganglioma patients: cost reduction strategy in genetic diagnostic process as fall-out. 19351833

2009
dbSNP: rs587778661
rs587778661
SDHC
T 0.700 GeneticVariation CLINVAR Whole exome sequencing is an efficient and sensitive method for detection of germline mutations in patients with phaeochromcytomas and paragangliomas. 24102379

2014
dbSNP: rs587778661
rs587778661
SDHC
T 0.700 GeneticVariation CLINVAR Toward an improved definition of the genetic and tumor spectrum associated with SDH germ-line mutations. 25394176

2015
dbSNP: rs587778661
rs587778661
SDHC
T 0.700 GeneticVariation CLINVAR Identification of eight novel SDHB, SDHC, SDHD germline variants in Danish pheochromocytoma/paraganglioma patients. 27279923

2016
dbSNP: rs587778661
rs587778661
SDHC
T 0.700 GeneticVariation CLINVAR A comprehensive next generation sequencing-based genetic testing strategy to improve diagnosis of inherited pheochromocytoma and paraganglioma. 23666964

2013
dbSNP: rs755235380
rs755235380
SDHC
G 0.700 CausalMutation CLINVAR Predictors and prevalence of paraganglioma syndrome associated with mutations of the SDHC gene. 16249420

2005
dbSNP: rs755235380
rs755235380
SDHC
G 0.700 CausalMutation CLINVAR Immunohistochemical loss of succinate dehydrogenase subunit A (SDHA) in gastrointestinal stromal tumors (GISTs) signals SDHA germline mutation. 23282968

2013
dbSNP: rs755235380
rs755235380
SDHC
G 0.700 CausalMutation CLINVAR Clinical predictors for germline mutations in head and neck paraganglioma patients: cost reduction strategy in genetic diagnostic process as fall-out. 19351833

2009