Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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A | 0.700 | CausalMutation | CLINVAR | Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. | 26681312 | 2016 |
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A | 0.700 | CausalMutation | CLINVAR | Clinical significance of frequent somatic mutations detected by high-throughput targeted sequencing in archived colorectal cancer samples. | 27146902 | 2016 |
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A | 0.700 | CausalMutation | CLINVAR | Identical TP53 mutations in pelvic carcinosarcomas and associated serous tubal intraepithelial carcinomas provide evidence of their clonal relationship. | 27059324 | 2016 |
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|
A | 0.700 | CausalMutation | CLINVAR | TP53 Mutational Status and Prediction of Benefit from Adjuvant 5-Fluorouracil in Stage III Colon Cancer Patients. | 26425688 | 2015 |
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|
A | 0.700 | CausalMutation | CLINVAR | TP53 mutation spectrum in breast cancer is subtype specific and has distinct prognostic relevance. | 24803582 | 2014 |
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A | 0.700 | CausalMutation | CLINVAR | Gastric cancer in individuals with Li-Fraumeni syndrome. | 21552135 | 2011 |
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|
A | 0.700 | CausalMutation | CLINVAR | Analysis of the DNA-binding activity of p53 mutants using functional protein microarrays and its relationship to transcriptional activation. | 20128691 | 2010 |
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A | 0.700 | CausalMutation | CLINVAR | Acute lymphoblastic leukemia after temozolomide treatment for anaplastic astrocytoma in a child with a germline TP53 mutation. | 20658636 | 2010 |
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|
A | 0.700 | CausalMutation | CLINVAR | Prevalence of early onset colorectal cancer in 397 patients with classic Li-Fraumeni syndrome. | 16401470 | 2006 |
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|
A | 0.700 | CausalMutation | CLINVAR | Predominantly tumor-limited expression of a mutant allele in a Japanese family carrying a germline p53 mutation. | 8134126 | 1994 |