rs80358721
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
Genetic variants of prospectively demonstrated phenocopies in BRCA1/2 kindreds.
|
29371908 |
2018 |
rs80358721
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
Implementation and utilization of the molecular tumor board to guide precision medicine.
|
28915716 |
2017 |
rs80358721
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
Use of Exome Sequencing for Infants in Intensive Care Units: Ascertainment of Severe Single-Gene Disorders and Effect on Medical Management.
|
28973083 |
2017 |
rs80358721
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
Malignant Brenner tumor associated with a germline BRCA2 mutation.
|
28616458 |
2017 |
rs80358721
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
|
26681312 |
2016 |
rs80358721
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
Clinical Next-Generation Sequencing Pipeline Outperforms a Combined Approach Using Sanger Sequencing and Multiplex Ligation-Dependent Probe Amplification in Targeted Gene Panel Analysis.
|
27376475 |
2016 |
rs80358721
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
Resistance to therapy in BRCA2 mutant cells due to loss of the nucleosome remodeling factor CHD4.
|
25737278 |
2015 |
rs80358721
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
Frequency of mutations in individuals with breast cancer referred for BRCA1 and BRCA2 testing using next-generation sequencing with a 25-gene panel.
|
25186627 |
2015 |
rs80358721
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
The contribution of deleterious germline mutations in BRCA1, BRCA2 and the mismatch repair genes to ovarian cancer in the population.
|
24728189 |
2014 |
rs80358721
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
Development and validation of a new algorithm for the reclassification of genetic variants identified in the BRCA1 and BRCA2 genes.
|
25085752 |
2014 |
rs80358721
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer.
|
23569316 |
2013 |
rs80358721
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
BRCA1/2 mutation analysis in 41 ovarian cell lines reveals only one functionally deleterious BRCA1 mutation.
|
23415752 |
2013 |
rs80358721
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
Predictive factors for BRCA1/BRCA2 mutations in women with ductal carcinoma in situ.
|
22009639 |
2012 |
rs80358721
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
EMMA, a cost- and time-effective diagnostic method for simultaneous detection of point mutations and large-scale genomic rearrangements: application to BRCA1 and BRCA2 in 1,525 patients.
|
21120943 |
2011 |
rs80358721
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
Secondary mutations of BRCA1/2 and drug resistance.
|
21205087 |
2011 |
rs80358721
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
Functional restoration of BRCA2 protein by secondary BRCA2 mutations in BRCA2-mutated ovarian carcinoma.
|
19654294 |
2009 |
rs80358721
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
Contribution of BRCA1 and BRCA2 mutations to inherited ovarian cancer.
|
17688236 |
2007 |