Gene: IL6 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1800795
rs1800795
IL6 ; STEAP1B ; IL6-AS1
0.030 GeneticVariation BEFREE However, to draw comprehensive and more reliable conclusions, further prospective studies with larger numbers of participants worldwide are needed to examine the association between rs1800795 polymorphism and knee OA. 24985590

2014
dbSNP: rs1800795
rs1800795
IL6 ; STEAP1B ; IL6-AS1
0.030 GeneticVariation BEFREE Data were analysed in conjuntion with published data on rs1800797 from the Genetics of OA and Lifestyle study (UK) on 791 controls, 1034 knee and 997 hip OA cases and rs1800795 data on 75 hip OA cases and 96 controls from Italy. 20175976

2010
dbSNP: rs1800795
rs1800795
IL6 ; STEAP1B ; IL6-AS1
0.030 GeneticVariation BEFREE The objective of this study was to investigate the relationship of the IL-6 promoter variants G-597A, G-572C and G-174C (rs1800797, rs1800796 and rs1800795, respectively), which have been shown to affect both the transcription and secretion of IL-6, to symptomatic distal interphalangeal (DIP) osteoarthritis (OA). 18257935

2008
dbSNP: rs1800796
rs1800796
IL6 ; STEAP1B ; IL6-AS1
0.020 GeneticVariation BEFREE Association of interleukin-6 gene polymorphism (rs1800796) with severity and functional status of osteoarthritis in elderly individuals. 26233477

2015
dbSNP: rs1800797
rs1800797
IL6 ; STEAP1B ; IL6-AS1
0.020 GeneticVariation BEFREE For knee OA the smallest P-value was seen for rs1800797 OR(Aallele)=1.055 (95%CI 0.98-1.12) P<0.18, no significant heterogeneity was observed (I(2)=0%, P<0.68). 20175976

2010
dbSNP: rs1800796
rs1800796
IL6 ; STEAP1B ; IL6-AS1
0.020 GeneticVariation BEFREE The objective of this study was to investigate the relationship of the IL-6 promoter variants G-597A, G-572C and G-174C (rs1800797, rs1800796 and rs1800795, respectively), which have been shown to affect both the transcription and secretion of IL-6, to symptomatic distal interphalangeal (DIP) osteoarthritis (OA). 18257935

2008
dbSNP: rs1800797
rs1800797
IL6 ; STEAP1B ; IL6-AS1
0.020 GeneticVariation BEFREE The objective of this study was to investigate the relationship of the IL-6 promoter variants G-597A, G-572C and G-174C (rs1800797, rs1800796 and rs1800795, respectively), which have been shown to affect both the transcription and secretion of IL-6, to symptomatic distal interphalangeal (DIP) osteoarthritis (OA). 18257935

2008