| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | GeneticVariation | BEFREE | In this meta-analysis, the results indicate the OPRM1 A118G polymorphism was associated with the opioid requirement and the adverse effects in pain treatment especially in postoperative pain. | 31337162 | 2019 |
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0.070 | GeneticVariation | BEFREE | OPRM1-A118G polymorphism (A > G, rs1799971) is associated with interindividual variability in both response to postoperative pain and opioid treatment. | 30323865 | 2018 |
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|
0.070 | GeneticVariation | BEFREE | Using multiple regression analyses, four single-nucleotide polymorphisms of COMT (rs6269, rs4633, rs4818, and rs4680), their haplotypes, and diplotypes were considered for their interactions with A118G of OPRM1 regarding postoperative pain and opioid consumption. | 27903758 | 2017 |
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|
0.070 | GeneticVariation | BEFREE | The OPRM1 A118G polymorphism may help predict individuals' response to epidural labor analgesia and so optimize postoperative pain control. | 23909491 | 2013 |
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|
0.070 | GeneticVariation | BEFREE | The aim of the study was to search for an association between the single-nucleotide polymorphisms A118G in OPRM1 and C3435T and G2677T/A in ABCB1 and the analgesic effect of intravenous oxycodone in postoperative pain. | 21383334 | 2012 |
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|
0.070 | GeneticVariation | BEFREE | This study shows that the OPRM1 118A>G polymorphism affects postoperative pain response in heterozygous patients: they have a different postoperative pain response than patients with wild-type genes, which may affect the efficacy of the analgesic therapy. | 22230405 | 2012 |
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0.070 | GeneticVariation | BEFREE | These results suggest that the A118G SNP may moderate but not mediate the effects of anger-out on postoperative pain responses. | 16400534 | 2006 |