|
rs4986790
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Thus, the aim of this study was to evaluate the influence of the <i>TLR4</i> A896G (rs4986790), <i>TLR4</i> C1196T (rs4986791), <i>CD14</i> C-260T (rs2569190), <i>RANKL</i> (<i>TNFSF11</i>, rs2277438), and <i>OPG</i> (<i>TNFSF11B</i> C163T, rs3102735) polymorphisms in periodontitis.
|
31281226 |
2019 |
|
rs4986790
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The TLR4 Asp299Gly SNP significantly interacted with P. gingivalis in conferring a decreased risk of periodontitis and may be protective against ABHL, a feature of periodontitis.
|
26174031 |
2016 |
|
rs4986790
|
|
|
0.090 |
GeneticVariation |
BEFREE |
For Asp299Gly polymorphism 1621 patients with periodontitis (1148 with CP and 473 with AgP) and 1755 individuals without clinical signs of periodontitis were included in the meta-analysis.
|
26771980 |
2016 |
|
rs4986790
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Meta-analysis of the TLR4 Asp299Gly and Thr399Ile polymorphisms showed no association between periodontitis and the TLR4 299Asp allele in all study subjects (OR=0.984, 95% CI=0.761-1.271, p=0.900; OR=1.030, 95% CI=0.748-1.418, p=0.854).
|
23653009 |
2013 |
|
rs4986790
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Our meta-analysis revealed that the two common TLR4 polymorphisms, Asp299Gly and Thr399Ile, have no association with the likelihood of periodontitis.
|
23879541 |
2013 |
|
rs4986790
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The prevalence of TLR2 Arp677Trp polymorphism seemed to be rather high, while that of TLR4 Asp299Gly and Thr399Ile polymorphisms seemed to be rather low in the Chinese population, which did not permit any conclusion regarding its effects on periodontitis.
|
18618036 |
2008 |
|
rs4986790
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The prevalence of the Asp299Gly and the Thr399Ile heterozygotes was 5.3% and 5.0% in controls, and 7.0% and 7.0% in periodontitis patients.
|
17559631 |
2007 |
|
rs4986790
|
|
|
0.090 |
GeneticVariation |
BEFREE |
No differences were found in the prevalence of the TLR4 Asp299Gly genotype in men with CP (18.9%) compared with an age-matched control group with no evidence of periodontitis (17%).
|
17309585 |
2007 |
|
rs4986790
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The prevalence of the Asp299Gly and the Thr399Ile mutant allele was 4.1% (10/244) and 4.5% (11/244) among periodontitis patients.
|
14738464 |
2004 |
|
rs4986791
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Thus, the aim of this study was to evaluate the influence of the <i>TLR4</i> A896G (rs4986790), <i>TLR4</i> C1196T (rs4986791), <i>CD14</i> C-260T (rs2569190), <i>RANKL</i> (<i>TNFSF11</i>, rs2277438), and <i>OPG</i> (<i>TNFSF11B</i> C163T, rs3102735) polymorphisms in periodontitis.
|
31281226 |
2019 |
|
rs4986791
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Evaluating the association of TLR4 polymorphisms (Asp299 and Thr399Ile) with the occurrence of periodontitis and its two clinical types: chronic (CP) and aggressive (AgP) among Caucasians.
|
26771980 |
2016 |
|
rs4986791
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Meta-analysis of the TLR4 Asp299Gly and Thr399Ile polymorphisms showed no association between periodontitis and the TLR4 299Asp allele in all study subjects (OR=0.984, 95% CI=0.761-1.271, p=0.900; OR=1.030, 95% CI=0.748-1.418, p=0.854).
|
23653009 |
2013 |
|
rs4986791
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Our meta-analysis revealed that the two common TLR4 polymorphisms, Asp299Gly and Thr399Ile, have no association with the likelihood of periodontitis.
|
23879541 |
2013 |
|
rs4986791
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The prevalence of TLR2 Arp677Trp polymorphism seemed to be rather high, while that of TLR4 Asp299Gly and Thr399Ile polymorphisms seemed to be rather low in the Chinese population, which did not permit any conclusion regarding its effects on periodontitis.
|
18618036 |
2008 |
|
rs4986791
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The prevalence of the Asp299Gly and the Thr399Ile mutant allele was 4.1% (10/244) and 4.5% (11/244) among periodontitis patients.
|
14738464 |
2004 |
|
rs1927911
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three SNPs of TLR4, i.e., rs1927911 (TT/CC+CT), rs2149356 (TT/GG+GT) and rs2737190 (GG/AA+AG), were associated with moderate/severe chronic periodontitis in Chinese population infected with <i>P. gingivalis</i>.<i>P. gingivalis</i>, which interacted with TLR4 gene plays an important role in the pathogenesis of periodontitis.
|
31772831 |
2019 |
|
rs2149356
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three SNPs of TLR4, i.e., rs1927911 (TT/CC+CT), rs2149356 (TT/GG+GT) and rs2737190 (GG/AA+AG), were associated with moderate/severe chronic periodontitis in Chinese population infected with <i>P. gingivalis</i>.<i>P. gingivalis</i>, which interacted with TLR4 gene plays an important role in the pathogenesis of periodontitis.
|
31772831 |
2019 |
|
rs7873784
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study demonstrated an association between TLR1-rs5743611, TLR4-rs7873784, TLR7-rs3853839, and TLR8-rs3764879 and susceptibility to periodontitis in adolescents.
|
30517775 |
2019 |
|
rs11536889
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We have previously shown that a single nucleotide polymorphism rs11536889 in the 3'-untranslated region (UTR) of TLR4 was associated with periodontitis.
|
22661708 |
2012 |