Gene: HLA-B ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12191877
rs12191877
HLA-B
0.830 GeneticVariation BEFREE Moreover, we replicated the association between rs12191877 (HLA-C) and type I psoriasis and between type I and type II psoriasis. 26613086

2015
dbSNP: rs12191877
rs12191877
HLA-B
0.830 GeneticVariation BEFREE The results of the univariate analysis showed an association between rs10484879 and psoriasis, although this relationship disappeared after adjustment for HLA-C (rs12191877). 26415694

2015
dbSNP: rs12191877
rs12191877
HLA-B
0.830 GeneticVariation GWASCAT Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2. 20953188

2010
dbSNP: rs12191877
rs12191877
HLA-B
0.830 GeneticVariation GWASDB Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2. 20953188

2010
dbSNP: rs12191877
rs12191877
HLA-B
0.830 GeneticVariation BEFREE The most significant finding was for SNP rs12191877, which is in tight linkage disequilibrium with HLA-Cw*0602, the consensus risk allele for psoriasis. 19680446

2009
dbSNP: rs12191877
rs12191877
HLA-B
T 0.830 GeneticVariation GWASCAT Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. 19169254

2009
dbSNP: rs12191877
rs12191877
HLA-B
T 0.830 GeneticVariation GWASDB Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. 19169254

2009
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
0.810 GeneticVariation BEFREE We investigated, in 461 psoriatic patients and 454 healthy controls, the associations with psoriasis of four single-nucleotide polymorphisms (SNPs) from the psoriasis susceptibility 1 (PSORS1) interval: rs1062470 (PSORS1C1/CDSN), rs887466 (PSORS1C3), rs2894207 and rs10484554 (LOC105375015). 29589160

2018
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
T 0.810 GeneticVariation GWASCAT Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture. 26626624

2015
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
0.810 GeneticVariation GWASDB A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. 20953190

2010
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
0.810 GeneticVariation GWASCAT A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. 20953190

2010
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
T 0.810 GeneticVariation GWASCAT A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci. 18369459

2008
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
T 0.810 GeneticVariation GWASDB A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci. 18369459

2008
dbSNP: rs4406273
rs4406273
HLA-B ; LINC02571 ; LOC112267902
0.800 GeneticVariation GWASDB Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. 23143594

2012
dbSNP: rs4406273
rs4406273
HLA-B ; LINC02571 ; LOC112267902
A 0.800 GeneticVariation GWASCAT Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. 23143594

2012
dbSNP: rs3134792
rs3134792
HLA-B
0.800 GeneticVariation GWASCAT Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene. 18364390

2008
dbSNP: rs3134792
rs3134792
HLA-B
0.800 GeneticVariation GWASDB Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene. 18364390

2008
dbSNP: rs3134792
rs3134792
HLA-B
0.800 GeneticVariation GWASDB Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis. 17587057

2007
dbSNP: rs12199223
rs12199223
HLA-B
0.700 GeneticVariation GWASCAT Genome-wide association study of psoriasis in an Egyptian population. 30921485

2019
dbSNP: rs2894207
rs2894207
HLA-B ; LINC02571
0.010 GeneticVariation BEFREE We investigated, in 461 psoriatic patients and 454 healthy controls, the associations with psoriasis of four single-nucleotide polymorphisms (SNPs) from the psoriasis susceptibility 1 (PSORS1) interval: rs1062470 (PSORS1C1/CDSN), rs887466 (PSORS1C3), rs2894207 and rs10484554 (LOC105375015). 29589160

2018
dbSNP: rs9266150
rs9266150
HLA-B ; MIR6891
0.010 GeneticVariation BEFREE Our results implied that rs9266150 might not only play an important role in the development of psoriasis, but also be positively associated with the geographic location, gender and present skin lesion in the Chinese population. 29630754

2018
dbSNP: rs12189871
rs12189871
HLA-B
0.010 GeneticVariation BEFREE Among identified psoriasis risk variants, three were more strongly associated with PsC than PsA (rs12189871 near HLA-C, p = 5.0 × 10(-19); rs4908742 near TNFRSF9, p = 0.00020; rs10888503 near LCE3A, p = 0.0014), and two were more strongly associated with PsA than PsC (rs12044149 near IL23R, p = 0.00018; rs9321623 near TNFAIP3, p = 0.00022). 26626624

2015
dbSNP: rs75912596
rs75912596
HLA-B ; HLA-C
0.010 GeneticVariation BEFREE Five common HERV-K dUTPase variants were found to be highly associated with psoriasis, with the strongest association occurring at the missense single-nucleotide polymorphism (SNP) rs3134774 (K158R, P=3.28 × 10(-15), odds ratio =2.36 (95% confidence interval: 1.91-2.92)). 22437317

2012
dbSNP: rs9468925
rs9468925
HLA-B
0.010 GeneticVariation BEFREE With four regression models obtained, two SNPs rs9468925 in HLA-C/HLA-B and rs2858881 in HLA-DQA2 were repeatedly selected in all models, suggesting that multiple loci outside PSOR1 locus were associated with psoriasis. 22125590

2011
dbSNP: rs281860350
rs281860350
HLA-B ; HLA-C
0.010 GeneticVariation BEFREE There was a significant trend for association with CSTA c.162T>C and psoriasis (odds ratio (OR)=3.45, P<0.001). 18364739

2008