Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11178997
rs11178997
TPH2
0.030 GeneticVariation BEFREE Also, there was a significant association of PTSD symptoms and the 't' allele of TPH2 SNP rs11178997 (p=0.03), explaining 4% of the variance. 22483952

2012
dbSNP: rs2108977
rs2108977
TPH1
0.010 GeneticVariation BEFREE After adjusting for age, sex, exposure and environmental variables, there was a significant association of PTSD symptoms with the 't' allele of TPH1 SNP rs2108977 (p<0.004), explaining 3% of the phenotypic variance. 22483952

2012
dbSNP: rs2295633
rs2295633
FAAH
0.010 GeneticVariation BEFREE We showed that rs2295633, a single-nucleotide polymorphism of FAAH, was significantly associated with PTSD diagnosis in subjects without lesions in the ventromedial prefrontal cortex. 22832737

2012
dbSNP: rs8042149
rs8042149
RORA
0.720 GeneticVariation GWASDB A genome-wide association study of post-traumatic stress disorder identifies the retinoid-related orphan receptor alpha (RORA) gene as a significant risk locus. 22869035

2013
dbSNP: rs4775301
rs4775301
RORA
0.700 GeneticVariation GWASDB A genome-wide association study of post-traumatic stress disorder identifies the retinoid-related orphan receptor alpha (RORA) gene as a significant risk locus. 22869035

2013
dbSNP: rs8024133
rs8024133
RORA
0.700 GeneticVariation GWASDB A genome-wide association study of post-traumatic stress disorder identifies the retinoid-related orphan receptor alpha (RORA) gene as a significant risk locus. 22869035

2013
dbSNP: rs8041061
rs8041061
RORA
0.700 GeneticVariation GWASDB A genome-wide association study of post-traumatic stress disorder identifies the retinoid-related orphan receptor alpha (RORA) gene as a significant risk locus. 22869035

2013
dbSNP: rs6265
rs6265
BDNF ; BDNF-AS
0.100 GeneticVariation BEFREE This study provides preliminary evidence for an epistatic interaction between BDNF Val66Met and DRD2 Taq1A polymorphisms on the severity of PTSD symptoms, where both too little and too much dopamine can result in increased PTSD symptom severity. 23103549

2013
dbSNP: rs759834365
rs759834365
BDNF ; BDNF-AS
0.100 GeneticVariation BEFREE This study provides preliminary evidence for an epistatic interaction between BDNF Val66Met and DRD2 Taq1A polymorphisms on the severity of PTSD symptoms, where both too little and too much dopamine can result in increased PTSD symptom severity. 23103549

2013
dbSNP: rs386231
rs386231
NOS1AP
0.010 GeneticVariation BEFREE Haplotype analysis revealed that the C/G haplotype (rs451275/rs386231) was significantly associated with PTSD (p=0.001). 23146198

2013
dbSNP: rs451275
rs451275
SPRY4-AS1
0.010 GeneticVariation BEFREE Haplotype analysis revealed that the C/G haplotype (rs451275/rs386231) was significantly associated with PTSD (p=0.001). 23146198

2013
dbSNP: rs6265
rs6265
BDNF ; BDNF-AS
0.100 GeneticVariation BEFREE This study provides the first evidence that the BDNF Val66Met genotype predicts response to cognitive behavior therapy in PTSD and is in accord with evidence that BDNF facilitates extinction learning. 23312562

2013
dbSNP: rs759834365
rs759834365
BDNF ; BDNF-AS
0.100 GeneticVariation BEFREE This study provides the first evidence that the BDNF Val66Met genotype predicts response to cognitive behavior therapy in PTSD and is in accord with evidence that BDNF facilitates extinction learning. 23312562

2013
dbSNP: rs2267735
rs2267735
ADCYAP1R1
0.050 GeneticVariation BEFREE The results indicated that although the rs2267735 'CC' genotype was not associated with total PTSD symptoms, it could significantly predict severity of PTSD's emotional numbing symptoms in women. 23394710

2013
dbSNP: rs1360780
rs1360780
FKBP5 ; LOC112267956
0.060 GeneticVariation BEFREE An African American cohort of adults (N = 103) was separated into 2 groups by genotype: one genotype group included carriers of the rs1360780 T allele, which has been associated with increased risk for posttraumatic stress disorder and affective disorders; the other group did not carry this allele. 23407841

2013
dbSNP: rs2267735
rs2267735
ADCYAP1R1
0.050 GeneticVariation BEFREE (2011); Nature 470:492-497] demonstrated that a variant, rs2267735, in the gene encoding PAC1 (ADCYAP1R1) is associated with post-traumatic stress disorder (PTSD) in a primarily African-American cohort of highly traumatized females. 23505260

2013
dbSNP: rs523349
rs523349
SRD5A2
0.010 GeneticVariation BEFREE Because SRD5A2 participates in the regulation of testosterone and cortisol metabolism, hormones shown to be dysregulated in patients with PTSD, we examined whether the V89L variant (rs523349) influences risk for post-traumatic stress disorder (PTSD). 23505265

2013
dbSNP: rs4576167
rs4576167
WWC1
0.010 GeneticVariation BEFREE An association of two neighboring SNPs in almost complete linkage disequilibrium, rs10038727 and rs4576167, with lifetime PTSD was discovered in the Rwandan sample. 23582269

2013
dbSNP: rs182455
rs182455
STMN1 ; LOC105376885
0.010 GeneticVariation BEFREE This study examined the association between STMN1 rs182455 genotype, a single nucleotide polymorphism (SNP) located within or close to the putative transcriptional control region of STMN1 gene, and PTSD symptoms. 23583473

2013
dbSNP: rs27072
rs27072
SLC6A3
0.010 GeneticVariation BEFREE The number of haplotypes (0, 1, or 2) defined by the presence of the nine repeat allele of rs28363170 (VNTR in the 3'UTR) and the C allele of rs27072 (SNP in the 3'UTR) was significantly associated with both the diagnosis of PTSD and total PTSD symptoms. 23647133

2013
dbSNP: rs28363170
rs28363170
SLC6A3
0.010 GeneticVariation BEFREE The number of haplotypes (0, 1, or 2) defined by the presence of the nine repeat allele of rs28363170 (VNTR in the 3'UTR) and the C allele of rs27072 (SNP in the 3'UTR) was significantly associated with both the diagnosis of PTSD and total PTSD symptoms. 23647133

2013
dbSNP: rs12364283
rs12364283
DRD2 ; LOC105369501
0.010 GeneticVariation BEFREE We found a functional DRD2 promoter polymorphism (rs12364283) to be most highly associated with PTSD liability [odds ratio (OR) 1.65 (1.27-2.15); P = 1.58 × 10(-4) ]; however, this association was not significant, with a stringent Bonferroni correction for multiple comparisons. 23647975

2014
dbSNP: rs16904179
rs16904179
CYRIB
0.800 GeneticVariation GWASCAT Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder. 23726511

2013
dbSNP: rs16904179
rs16904179
CYRIB
0.800 GeneticVariation GWASDB Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder. 23726511

2013
dbSNP: rs406001
rs406001 		0.800 GeneticVariation GWASCAT Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder. 23726511

2013