rs1799971
|
|
|
0.020 |
GeneticVariation |
BEFREE |
There were no significant associations observed for <i>DRD2</i> rs1076560 SNP, <i>OPRM1</i> rs1799971 SNP, and combined genotypes of both SNPs in the SUD group.
|
29881439 |
2018 |
rs4680
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Facial emotion recognition in schizophrenia: An exploratory study on the role of comorbid alcohol and substance use disorders and COMT Val158Met.
|
28913946 |
2017 |
rs4680
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Executive control in schizophrenia: a preliminary study on the moderating role of COMT Val158Met for comorbid alcohol and substance use disorders.
|
28635556 |
2017 |
rs1799971
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Compared to controls, ADHD patients (with and without SUDs) showed significantly increased frequency of the DBH (rs2519152: OR 1.73; CI 1.15-2.59; P=0.008) and the OPRM1 risk genotypes (rs1799971: OR 1.71; CI 1.17-2.50; P=0.006).
|
22841130 |
2013 |
rs324420
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This may explain the greater vulnerability for addiction and obesity in individuals with C385A genetic variant and by extension, suggest that a D3 antagonism strategy in substance use disorders should consider FAAH C385A polymorphism.
|
31775159 |
2020 |
rs9296158
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Working memory reflects vulnerability to early life adversity as a risk factor for substance use disorder in the FKBP5 cortisol cochaperone polymorphism, rs9296158.
|
31185043 |
2019 |
rs1076560
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study is the first study to determine the allele frequency and the genetic association of the <i>DRD2</i> rs1076560 SNP and <i>OPRM1</i> rs1799971 SNP variants in clinically diagnosed patients with SUD from the United Arab Emirates (UAE).
|
29881439 |
2018 |
rs11568817
|
|
|
0.010 |
GeneticVariation |
BEFREE |
As for the comorbidities evaluated, after correction for multiple tests, significant associations were observed for both rs11568817 and rs130058 with substance use disorders (P<sub>corr</sub> = 0.009 and P<sub>corr</sub> = 0.018, respectively) and for rs11568817 with nicotine dependence (P<sub>corr</sub> = 0.025) in men with ADHD.
|
28923721 |
2017 |
rs130058
|
|
|
0.010 |
GeneticVariation |
BEFREE |
As for the comorbidities evaluated, after correction for multiple tests, significant associations were observed for both rs11568817 and rs130058 with substance use disorders (P<sub>corr</sub> = 0.009 and P<sub>corr</sub> = 0.018, respectively) and for rs11568817 with nicotine dependence (P<sub>corr</sub> = 0.025) in men with ADHD.
|
28923721 |
2017 |
rs6277
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This work has implications for a number of psychiatric conditions in which dopamine signaling and variation in C957T status have been implicated, including schizophrenia and substance use disorders.
|
28398340 |
2017 |
rs2402959
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Single and multiple marker analyses revealed association between two SNPs located at the 3' region of miR-96 (rs2402959 and rs6965643) and ADHD without SUD.
|
23906647 |
2013 |
rs2519152
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Compared to controls, ADHD patients (with and without SUDs) showed significantly increased frequency of the DBH (rs2519152: OR 1.73; CI 1.15-2.59; P=0.008) and the OPRM1 risk genotypes (rs1799971: OR 1.71; CI 1.17-2.50; P=0.006).
|
22841130 |
2013 |
rs373611092
|
|
|
0.010 |
GeneticVariation |
BEFREE |
One hundred seven methadone maintenance treatment patients, 36 having an ADHD diagnosis, 176 adult patients with ADHD without SUDs, and 500 healthy controls were genotyped for variants in the DRD4 (exon 3 VNTR), DRD5 (upstream VNTR), HTR1B (rs6296), DBH (rs2519152), COMT (rs4680; Val158Met), and OPRM1 (rs1799971; 118A>G) genes.
|
22841130 |
2013 |
rs6965643
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Single and multiple marker analyses revealed association between two SNPs located at the 3' region of miR-96 (rs2402959 and rs6965643) and ADHD without SUD.
|
23906647 |
2013 |
rs1800497
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A total of 110 adult patients with ASD (n=61) or ADHD (n=49) with or without a lifetime history of SUD participated in a study in which we genotyped polymorphisms in five known candidate genes for (one of) the disorders, i.e. the 5HTTLPR in SLC6A4/5-HTT, rs1800497 (TaqIA C>T) in DRD2, rs7794745 in CNTNAP2, rs1843809 in TPH2, and rs6565113 in CDH13.
|
20446882 |
2010 |
rs1843809
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A total of 110 adult patients with ASD (n=61) or ADHD (n=49) with or without a lifetime history of SUD participated in a study in which we genotyped polymorphisms in five known candidate genes for (one of) the disorders, i.e. the 5HTTLPR in SLC6A4/5-HTT, rs1800497 (TaqIA C>T) in DRD2, rs7794745 in CNTNAP2, rs1843809 in TPH2, and rs6565113 in CDH13.
|
20446882 |
2010 |
rs6565113
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A total of 110 adult patients with ASD (n=61) or ADHD (n=49) with or without a lifetime history of SUD participated in a study in which we genotyped polymorphisms in five known candidate genes for (one of) the disorders, i.e. the 5HTTLPR in SLC6A4/5-HTT, rs1800497 (TaqIA C>T) in DRD2, rs7794745 in CNTNAP2, rs1843809 in TPH2, and rs6565113 in CDH13.
|
20446882 |
2010 |
rs7794745
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A total of 110 adult patients with ASD (n=61) or ADHD (n=49) with or without a lifetime history of SUD participated in a study in which we genotyped polymorphisms in five known candidate genes for (one of) the disorders, i.e. the 5HTTLPR in SLC6A4/5-HTT, rs1800497 (TaqIA C>T) in DRD2, rs7794745 in CNTNAP2, rs1843809 in TPH2, and rs6565113 in CDH13.
|
20446882 |
2010 |