Gene: TLR4 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4986790
rs4986790
TLR4
0.060 GeneticVariation BEFREE In conclusion, our data suggest that TLR4 (D299G and T399I) and TNF (-308G/A) genetic polymorphisms may influence the risk of developing tuberculosis after exposure to Mycobacterium. 26774366

2016
dbSNP: rs4986790
rs4986790
TLR4
0.060 GeneticVariation BEFREE The present meta-analysis suggests that TLR4 gene Asp299Gly and Thr399Ile polymorphisms are not associated with the susceptibility of tuberculosis. 23200920

2013
dbSNP: rs4986790
rs4986790
TLR4
0.060 GeneticVariation BEFREE Polymorphisms of the toll-like receptor 2 (TLR2) gene (Arg677Trp, Arg753Gln) and the TLR4 gene (Asp299Gly, Thr399Ile) were investigated in 205 tuberculosis (TB) patients and 203 controls. 20002809

2010
dbSNP: rs4986790
rs4986790
TLR4
0.060 GeneticVariation BEFREE We describe an independent association between TLR4 Asp299Gly SNP and active TB in Caucasian Mediterranean HIV-infected patients. 20226000

2010
dbSNP: rs4986790
rs4986790
TLR4
0.060 GeneticVariation BEFREE We found a greater risk of developing active tuberculosis as well as a reduction in CD4 T-cell counts in patients with the Asp299Gly TLR4 polymorphism. 17545720

2007
dbSNP: rs4986790
rs4986790
TLR4
0.060 GeneticVariation BEFREE Our data suggest that TLR4 Asp299Gly has no influence on monocyte LPS responses or susceptibility to TB in Gambians and could be an ancient neutral polymorphism. 15525557

2004
dbSNP: rs4986791
rs4986791
TLR4
0.050 GeneticVariation BEFREE In conclusion, our data suggest that TLR4 (D299G and T399I) and TNF (-308G/A) genetic polymorphisms may influence the risk of developing tuberculosis after exposure to Mycobacterium. 26774366

2016
dbSNP: rs4986791
rs4986791
TLR4
0.050 GeneticVariation BEFREE The T allele of TLR4 rs4986791 was also found to increase the risk of TB in the Asian subgroup. 26430737

2015
dbSNP: rs4986791
rs4986791
TLR4
0.050 GeneticVariation BEFREE The present meta-analysis suggests that TLR4 gene Asp299Gly and Thr399Ile polymorphisms are not associated with the susceptibility of tuberculosis. 23200920

2013
dbSNP: rs4986791
rs4986791
TLR4
0.050 GeneticVariation BEFREE The association between two particular SNPs in human TLR4 (Asp299Gly and Thr399Ile) and active TB has been studied in non-HIV Africans with contradictory results. 20226000

2010
dbSNP: rs4986791
rs4986791
TLR4
0.050 GeneticVariation BEFREE Polymorphisms of the toll-like receptor 2 (TLR2) gene (Arg677Trp, Arg753Gln) and the TLR4 gene (Asp299Gly, Thr399Ile) were investigated in 205 tuberculosis (TB) patients and 203 controls. 20002809

2010
dbSNP: rs754342091
rs754342091
TLR4
0.010 GeneticVariation BEFREE In conclusion, our data suggest that TLR4 (D299G and T399I) and TNF (-308G/A) genetic polymorphisms may influence the risk of developing tuberculosis after exposure to Mycobacterium. 26774366

2016