rs17003221
|
|
|
0.020 |
GeneticVariation |
BEFREE |
It is concluded from the present study that the genotypes CT and TT from BMP15:c.852C>T variation may be risk factors for the development of POI.
|
31392662 |
2019 |
rs17003221
|
|
|
0.020 |
GeneticVariation |
BEFREE |
A total of three SNPs were detected within the BMP15 gene, including rs3810682 (-9C>G), rs79377927 (788_789insTCT) and rs17003221 (852C>T), and no significant differences were observed in the frequencies of the -9C>G and 852C>T genotypes between the POF and control groups (7.94, vs. 6.90% and 4.76, vs. 3.45%, respectively).
|
25954833 |
2015 |
rs104894767
|
|
|
0.020 |
GeneticVariation |
BEFREE |
BMP15 538G>A was found to be significantly more common in patients with POF compared with controls.
|
25445105 |
2014 |
rs104894767
|
|
|
0.020 |
GeneticVariation |
BEFREE |
One variant (A180T) was identified among two POF cases, and also in two controls.
|
20364024 |
2010 |
rs3810682
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A total of three SNPs were detected within the BMP15 gene, including rs3810682 (-9C>G), rs79377927 (788_789insTCT) and rs17003221 (852C>T), and no significant differences were observed in the frequencies of the -9C>G and 852C>T genotypes between the POF and control groups (7.94, vs. 6.90% and 4.76, vs. 3.45%, respectively).
|
25954833 |
2015 |
rs79377927
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These results demonstrated that GDF9 c.169G>T (D57Y), c.546G>A (rs1049127), and BMP15 rs79377927 (788_789insTCT) were associated with POF in the Chinese Hui population.
|
25954833 |
2015 |
rs104894765
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Interestingly, the Y235C mutation was previously identified in association with POI in women.
|
24147118 |
2013 |
rs141218518
|
|
|
0.010 |
GeneticVariation |
BEFREE |
One variant (F194S), predicted as potentially deleterious, was identified for the first time in a POF patient but also identified in one control.
|
20364024 |
2010 |
rs782609889
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, three single nucleotide polymorphisms in the BMP15 gene, two in the 5' untranslated region (31T>G and 71C>G) and another in exon 1 (387G>A), were found to be common in both POF and control groups.
|
17027369 |
2006 |