|
rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The M235T variant of the AGT is significantly associated with female hypertensives and ACE DD variant could be a risk allele for essential hypertension in south India.
|
24860821 |
2014 |
|
rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We determined the association of angiotensinogen (M235T) gene polymorphism with essential hypertension and the relationship between polymorphism in the angiotensinogen (M235T) gene and blood pressure response to ACE inhibitor (Enalapril) in patients with essential hypertension from northern Indian subjects.
|
22974788 |
2012 |
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rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We studied the effects of the angiotensinogen M235T, angiotensin converting enzyme insertion/deletion (ACE I/D), and angiotensin II receptor 1 (AT1R) A1166C gene polymorphisms on the risk of HTA and to evaluate the relationship between these polymorphisms and obesity.
|
21779803 |
2012 |
|
rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The present meta-analysis suggests that AGT M235T and ACE I/D modulate the risk of essential hypertension in Han Chinese population.
|
20087216 |
2010 |
|
rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Although polymorphisms in renin-angiotensin-aldosterone (RAA) system genes for angiotensinogen (AGT M235T), angiotensin-converting enzyme (ACE I/D), angiotensin II type 1 receptor (AT1 A/C1166), and aldosterone synthase (CYP11B2-344T/C) have been major targets for genetic investigation in association with essential hypertension (EH), the influence of these genetic factors is still to be determined.
|
17190732 |
2007 |
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rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We investigated if renin-angiotensinaldosterone system associated genotypes (angiotensinogen [M235T] and ACE [I/D]) are related to blood pressure (BP), renal haemodynamics and sodium excretion in sex and age-matched (1835 years) healthy Caucasian offspring of either two parents with EH (n=101, EH-offspring) or two normotensive parents (n=50, controls).
|
17083073 |
2006 |
|
rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The results of our study suggest an association of the M235T polymorphism in the gene encoding angiotensinogen with essential hypertension.
|
12169209 |
2003 |
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rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The ACE (I/D) polymorphism showed no association with CHD, whereas the frequency distribution of AGT (M235T) genotypes among patients and controls (235T: 29.1% and 19.0%; M235T: 48.5% and 50.2%; M235: 22.4% and 30.8%, respectively) was statistically different (p = 0.005) and not related to the presence of essential hypertension.
|
11345362 |
2001 |
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rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We therefore investigated the association between ACE I/D, AGT M235T, and AT1 A1266C gene polymorphisms and early signs of target organ damage in 215 untreated patients with essential hypertension (EH).
|
10652033 |
2000 |
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rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We conclude that the interaction of the I/D ACE and M235T AGT polymorphic alleles can contribute to essential hypertension, despite the absence of single gene associations with the condition.
|
9607178 |
1998 |
|
rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In the present study we examined the genotype frequencies of the insertion/deletion polymorphisms of the ACE gene and the M235T polymorphism of the Angiotensinogen (Agt) gene in patients with essential hypertension in comparison with normotensive subjects.
|
9524045 |
1998 |
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rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
To examine whether the angiotensinogen M235T and angiotensin converting enzyme insertion/deletion (I/D) variants are related to the severity of hypertension in patients with established essential hypertension.
|
9170002 |
1997 |
|
rs1267969615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Two molecular variants of the angiotensinogen gene, one encoding threonine instead of methionine at position 235 (M235T) and the other encoding methionine rather than threonine at position 174 (T174M), were also tested for possible association with essential hypertension.
|
8177268 |
1994 |
|
rs1415088003
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Interaction between GNB3 C825T and ACE I/D polymorphisms in essential hypertension in Koreans.
|
17066084 |
2007 |
|
rs1415088003
|
|
|
0.040 |
GeneticVariation |
BEFREE |
GNB3 C825T and ACE I/D polymorphisms on the sodium-proton exchanger and the prevalence of essential hypertension in males.
|
16314202 |
2006 |
|
rs1415088003
|
|
|
0.040 |
GeneticVariation |
BEFREE |
GNB3 gene C825T and ACE gene I/D polymorphisms in essential hypertension in a Kazakh genetic isolate.
|
15042113 |
2004 |
|
rs1415088003
|
|
|
0.040 |
GeneticVariation |
BEFREE |
In 34 white patients with established mild to moderate essential hypertension (World Health Organization stage I or II, mean age 52 +/- 9 years) genotype analysis of GNB3 C825T polymorphism, insertion/deletion polymorphism of the ACE gene and 1166 A/C polymorphism of the AT1 receptor gene was performed.
|
10526907 |
1999 |
|
rs12720742
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Both newly detected TSC C1784T and ADRB3 T727C are gene polymorphisms susceptible to the antihypertensive effect of TZDs in patients with EHT.
|
15824464 |
2004 |
|
rs12720742
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Allelic variants in the genes for angiotensinogen, alpha-adducin, beta2-adrenergic receptor, the G-protein beta3-subunit and the T594M mutation in the beta-subunit of the epithelial sodium channel have been identified; however, the importance of these allelic variants to primary hypertension as a whole, is not yet clear.
|
9886871 |
1998 |
|
rs1221928144
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This is the first report showing that the S89N single-nucleotide polymorphism of the UTS2 gene is associated with essential hypertension.
|
16866021 |
2007 |
|
rs568401628
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of Trp64Arg beta 3-adrenergic-receptor gene polymorphism with essential hypertension in the Sardinian population.
|
10100091 |
1999 |