|
rs120074187
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs1554108172
|
|
T |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs766265889
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs3745297
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The histidine-rich calcium-binding protein (HRC) Ser96Ala variant has previously been identified as a potential biomarker for ventricular arrhythmias and sudden cardiac death in patients with idiopathic dilated cardiomyopathy.
|
28859293 |
2017 |
|
rs3745297
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The common Ser96Ala human genetic variant of HRC strongly correlates with life-threatening ventricular arrhythmias in patients with idiopathic dilated cardiomyopathy.
|
28784772 |
2017 |
|
rs3745297
|
|
|
0.050 |
GeneticVariation |
BEFREE |
A human genetic variant (Ser96Ala) in the sarcoplasmic reticulum (SR) histidine-rich Ca(2+)-binding (HRC) protein has been linked to ventricular arrhythmia and sudden death in dilated cardiomyopathy.
|
24125847 |
2013 |
|
rs3745297
|
|
|
0.050 |
GeneticVariation |
BEFREE |
These findings indicate that the HRC Ser96Ala variant increases the propensity of arrhythmogenic Ca(2+) waves in the stressed failing heart, suggesting a link between this genetic variant and life-threatening ventricular arrhythmias in human carriers.
|
21742996 |
2011 |
|
rs3745297
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The Ser96Ala genetic variant of HRC is associated with life-threatening ventricular arrhythmias in idiopathic DCM and may serve as an independent predictor of susceptibility to arrhythmogenesis in the setting of DCM.
|
18617481 |
2008 |
|
rs3766871
|
|
|
0.020 |
GeneticVariation |
BEFREE |
RyR2 Common Gene Variant G1886S and the Risk of Ventricular Arrhythmias in ICD Patients with Heart Failure.
|
25773045 |
2015 |
|
rs7626962
|
|
|
0.020 |
GeneticVariation |
BEFREE |
This is the first report that the S1103Y variant is associated with a higher incidence of ventricular arrhythmias in blacks with heart failure and reduced ejection fraction.
|
21498565 |
2011 |
|
rs3766871
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, the A allele of rs3766871 in RYR2 not only associates with ventricular arrhythmias, but also serves as an independent predictor of sudden cardiac death, and the A allele of rs790896 in RYR2 is a protective factor against sudden cardiac death in patients with CHF.
|
20408814 |
2010 |
|
rs7626962
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our study shows that mutation S1103Y does exist in the white population, and it is associated with a considerable risk of syncope, ventricular arrhythmia, ventricular fibrillation, and sudden death in this population.
|
12471205 |
2002 |
|
rs1049194905
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The association study identified a statistically significant difference in genotype frequency of KCNH2: c.1539C>T and KCNH2: c.1467C>T between the AMI and AMI_VA groups.
|
31751991 |
2020 |
|
rs1237080661
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The association study identified a statistically significant difference in genotype frequency of KCNH2: c.1539C>T and KCNH2: c.1467C>T between the AMI and AMI_VA groups.
|
31751991 |
2020 |
|
rs1805120
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The association study identified a statistically significant difference in genotype frequency of KCNH2: c.1539C>T and KCNH2: c.1467C>T between the AMI and AMI_VA groups.
|
31751991 |
2020 |
|
rs184934308
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, 2 rare variants (KCNQ1: c.1944C>T and SCN5A: c.3621C>T) showed an elevated allelic frequency (more than 1.5-fold) in the AMI_VA group when compared to the AMI group.
|
31751991 |
2020 |
|
rs201698592
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, 2 rare variants (KCNQ1: c.1944C>T and SCN5A: c.3621C>T) showed an elevated allelic frequency (more than 1.5-fold) in the AMI_VA group when compared to the AMI group.
|
31751991 |
2020 |
|
rs740952
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The association study identified a statistically significant difference in genotype frequency of KCNH2: c.1539C>T and KCNH2: c.1467C>T between the AMI and AMI_VA groups.
|
31751991 |
2020 |
|
rs750678689
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, 2 rare variants (KCNQ1: c.1944C>T and SCN5A: c.3621C>T) showed an elevated allelic frequency (more than 1.5-fold) in the AMI_VA group when compared to the AMI group.
|
31751991 |
2020 |
|
rs1355262401
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In heterozygous mice with S282 gene substituted with alanine (S282A), we found ventricular arrhythmias with inhibition of Cx43 phosphorylation at both S282 and S279 in the hearts.
|
30981509 |
2019 |
|
rs764772142
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A pathogenic mutation in RYR2 (p.P164S) is the likely cause of USD in a Chinese family associated with malignant ventricular arrhythmias.
|
29132927 |
2019 |
|
rs120074192
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, the KCNQ1 S140G mutation can induce ventricular arrhythmia and lessen ventricular contractility under re-entrant conditions.
|
30108508 |
2018 |
|
rs192749597
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We identified a loss-of-function variant, Ca<sub>v</sub>α<sub>1c</sub>-T1787M, present in 0.8% of the African population, as a new risk factor for ventricular arrhythmia.
|
30279520 |
2018 |
|
rs45546039
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Rapid and effective response of the R222Q SCN5A to quinidine treatment in a patient with Purkinje-related ventricular arrhythmia and familial dilated cardiomyopathy: a case report.
|
29871609 |
2018 |
|
rs755373114
|
|
|
0.010 |
GeneticVariation |
BEFREE |
KI mice harboring the p.Q1283H variant exhibited an increased predisposition to ventricular arrhythmias after catecholaminergic stress in the absence of cardiac structural abnormalities.
|
30571258 |
2018 |