Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1816158
rs1816158
0.010 GeneticVariation BEFREE Joint population analyses identified novel miR-SNPs associated with overall survival in oral and laryngeal cancers. rs1816158, located within long noncoding RNA <i>MIR100HG</i>, was associated with overall survival in oral cavity cancer (HR, 1.56; 95% confidence interval (CI), 1.21-2.00). 29880533

2019

dbSNP: rs1373756
rs1373756
0.010 GeneticVariation BEFREE Four other variants were specifically associated with oral cavity cancer risk (rs16914640, rs1134367, rs7306991 and rs1373756). 28582492

2017

dbSNP: rs16914640
rs16914640
0.010 GeneticVariation BEFREE Four other variants were specifically associated with oral cavity cancer risk (rs16914640, rs1134367, rs7306991 and rs1373756). 28582492

2017

dbSNP: rs1864183
rs1864183
0.010 GeneticVariation BEFREE We found an association between the variant in ATG10 rs1864183 and a higher susceptibility to develop laryngeal cancer, ATG2B rs3759601 and pharyngeal cancer and ATG16L1 rs2241880 and oral carcinoma. 28761177

2017

dbSNP: rs2241880
rs2241880
0.010 GeneticVariation BEFREE We found an association between the variant in ATG10 rs1864183 and a higher susceptibility to develop laryngeal cancer, ATG2B rs3759601 and pharyngeal cancer and ATG16L1 rs2241880 and oral carcinoma. 28761177

2017

dbSNP: rs3759601
rs3759601
0.010 GeneticVariation BEFREE We found an association between the variant in ATG10 rs1864183 and a higher susceptibility to develop laryngeal cancer, ATG2B rs3759601 and pharyngeal cancer and ATG16L1 rs2241880 and oral carcinoma. 28761177

2017

dbSNP: rs7834169
rs7834169
0.010 GeneticVariation BEFREE An upstream variant of MIR548H4 (rs7834169), replicated its association with overall HNSCC risk as well as risk of oral cavity cancer. 28582492

2017

dbSNP: rs221236
rs221236
0.010 GeneticVariation BEFREE These findings indicated that rs221236 located at Lin28B may contribute to the risk of oral cavity cancer through the interruption of miRNA binding. 25503985

2014

dbSNP: rs221636
rs221636
0.010 GeneticVariation BEFREE We found that the variant allele (T) of rs221636 of Lin28B was significantly associated with a reduced risk of oral cavity cancer [odds ratio (OR) = 0.73, 95% confidence interval (CI) = 0.58-0.92, P = 7.55 × 10(-3) in additive model]. 25503985

2014

dbSNP: rs2274223
rs2274223
0.010 GeneticVariation BEFREE We found that rs2274223 was associated with a significantly increased risk of HNC in our population [GG vs. AA: adjusted odds ratio (OR)=1.86, 95% confidence interval (CI)=1.09-3.16; GG vs. (AG/AA): adjusted OR=1.85, 95% CI=1.09-3.12], and the effect appeared to be more prominent among drinkers (P=0.024) and patients with oral cavity cancer (P=0.019). 23151416

2013

dbSNP: rs1048943
rs1048943
0.010 GeneticVariation BEFREE Cytochrome P450 1A1 Ile462Val polymorphism and oral carcinoma risk: an updated meta-analysis including 1,515 cases and 2,233 controls. 22847262

2012

dbSNP: rs1217691063
rs1217691063
0.010 GeneticVariation BEFREE Polymorphisms of MTHFR C677T and A1298C association with oral carcinoma risk: a meta-analysis. 22536935

2012

dbSNP: rs2238135
rs2238135
VDR
0.010 GeneticVariation BEFREE Furthermore, the G/C genotype of the rs2238135 in the VDR gene was characterized by a 3.16 fold increased risk of oral cavity carcinoma</span>. 23189278

2012

dbSNP: rs2910164
rs2910164
0.010 GeneticVariation BEFREE Association between the rs2910164 polymorphism in pre-mir-146a and oral carcinoma progression. 22182931

2012

dbSNP: rs397507444
rs397507444
0.010 GeneticVariation BEFREE Polymorphisms of MTHFR C677T and A1298C association with oral carcinoma risk: a meta-analysis. 22536935

2012

dbSNP: rs1271546630
rs1271546630
MPO
0.010 GeneticVariation BEFREE The aim of this study was to evaluate the risks of the polymorphisms of oxidant stress-related enzymes on patients with oral cavity cancer by genotyping of manganese superoxide dismutase (MnSOD [1183T>C]), myeloperoxidase (MPO [-463G>A]), catalase (CAT [-15A>T]) and glutathione peroxidases 1 (GPx1 [Pro198Leu]). 20643115

2010