rs1799883
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The alanine to threonine amino acid substitution at codon 54 (Ala54Thr) of the intestinal fatty acid binding protein (FABP2) has been associated with elevated levels of insulin and blood glucose as well as with dyslipidemia.
|
26703680 |
2015 |
rs1799883
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The results from the published studies on the association of fatty acid-binding protein 2 (FABP2) Ala54Thr polymorphism with dyslipidemia are conflicting and inconclusive.
|
20047744 |
2010 |
rs1799883
|
|
|
0.050 |
GeneticVariation |
BEFREE |
To investigate whether or not the intestinal fatty acid binding protein gene (FABP2)-Ala54Thr variation is related to non-insulin dependent diabetes mellitus (NIDDM), obesity, dyslipidemia and glucose stimulated insulin secretion (GSIS) in Chinese.
|
11593593 |
1999 |
rs1799883
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Our data suggested that Ala54Thr polymorphism of the FABP2 gene is not a major contributing factor for obesity and obesity with dyslipidemia in Japanese children.
|
11866034 |
2001 |
rs1799883
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Our objectives were to determine whether Ala54Thr FABP2 and G-493T MTP polymorphisms are associated with increased risks of insulin resistance syndrome (IRS) in youth and/or modify the expression of accompanying dyslipidemia.
|
15547295 |
2005 |
rs1217691063
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Further studies are needed to confirm the role of tHcy and the MTHFR C677T mutation in the development of dyslipidemia in a larger sample.
|
26442927 |
2017 |
rs1217691063
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The aim of the present study was to evaluate the effect of simvastatin treatment on circulating Hcy levels in obese women without hypertension, diabetes or dyslipidaemia; and to determine whether the 677C>T polymorphism located in methylenetetrahydrofolate reductase (NAD(P)H) (MTHFR) gene modulates the effects of this treatment on Hcy and nitrite (as a biomarker of nitric oxide (NO) bioavailability).
|
25115547 |
2014 |
rs1217691063
|
|
|
0.040 |
GeneticVariation |
BEFREE |
In conclusion, in these type 2 diabetic outpatients circulating levels of tHcy, folate, and the MTHFR C677T mutation are not associated with DPN, which was predicted by creatinine levels, CHD, and dyslipidemia.
|
26233336 |
2016 |
rs1217691063
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Supplementation with Watermelon Extract Reduces Total Cholesterol and LDL Cholesterol in Adults with Dyslipidemia under the Influence of the MTHFR C677T Polymorphism.
|
26934084 |
2016 |
rs1260326
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We evaluated, in a general French population, the contribution of the GCKR rs1260326-P446L polymorphism to quantitative metabolic parameters and to dyslipidemia and hyperglycemia risk.
|
18556336 |
2008 |
rs1260326
|
|
|
0.030 |
GeneticVariation |
BEFREE |
A polymorphism in the GCKR gene predicted dyslipidaemia (rs1260326, OR 1.15, 95% CI 1.09-1.22, p < 0.00001) but not the metabolic syndrome.
|
18853134 |
2008 |
rs1260326
|
|
|
0.030 |
GeneticVariation |
BEFREE |
There were significant associations between rs1260333 (OR is 0.82, 95 % CI 0.74-0.92, p ~ 3.96 × 10(-4)), rs1260326 (OR is 0.82, 95 % CI 0.74-0.92, p ~ 5.31 × 10(-4)), and rs964184 (OR is 1.36, 95 % CI 1.20-1.55, p ~ 1.89 × 10(-6)) and dyslipidemia.
|
23832694 |
2013 |
rs1800206
|
|
|
0.030 |
GeneticVariation |
BEFREE |
When the most common haplotype L-G (established by r</span>s1800206, rs4253778) was treated as the reference group, the V-G haplotype was associated with dyslipidemia (P < 0.001), higher TC and TG levels (P < 0.01).
|
24460649 |
2014 |
rs1800206
|
|
|
0.030 |
GeneticVariation |
BEFREE |
In addition, the Leu162Val polymorphism was not associated with WHO-defined obesity or dyslipidaemia in case-control settings involving 961 obese and 2563 lean subjects and 1399 dyslipidaemic and 4399 normolipidaemic subjects, respectively.
|
17129741 |
2007 |
rs1800206
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The present study was performed to evaluate the association between the PPARalpha polymorphism L162V and the presence of dyslipidemia and/or atherosclerotic disease in patients with DM-2 in comparison with nondiabetic controls.
|
15199365 |
2004 |
rs268
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Carriers of N291S or D9N missense mutations in the lipoprotein lipase (LPL) gene exhibit reductions in LPL activity and are predisposed to dyslipidemia and cardiovascular disease.
|
10636447 |
1999 |
rs268
|
|
|
0.030 |
GeneticVariation |
BEFREE |
There was a significant interaction between Asn291Ser and insulin resistance in normoglycaemic subjects, indicating that dyslipidaemia is more severe in Asn/ Ser carriers with reduced insulin sensitivity.
|
11073182 |
2000 |
rs268
|
|
|
0.030 |
GeneticVariation |
BEFREE |
This meta-analysis indicates that the Asn291Ser variant in the LPL gene is a risk factor for dyslipidemia, characterized by hypertriglyceridemia and low HDL-C levels.
|
16741292 |
2006 |
rs662799
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The objective of this study was to analyze the interaction of a high fat diet with the APOA2 (rs3813627 and rs5082), APOA5 (rs662799 and rs3135506) and LEPR (rs8179183 and rs1137101) polymorphisms and its relationship with obesity and dyslipidemia in young subjects.
|
26365669 |
2015 |
rs662799
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Multivariable logistic regression analysis of combined genotypes with adjustment for age, gender and diabetes mellitus revealed that rs662799 and rs6929846 significantly and synergistically affected dyslipidemia.
|
22576629 |
2012 |
rs662799
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our data indicate that the rs662799 polymorphism is associated with dyslipidemia and the severity of CHD in Chinese women.
|
27716220 |
2016 |
rs670
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Results revealed significant differences in rs670 and rs2292318 allele frequencies between cases and controls (P<0.025). rs670 G allele carriers were more likely to develop dyslipidemia than A allele carriers (OR = 1.315, OR 95% CI: 1.067-2.620; P = 0.010). rs2292318 T allele carriers were more likely to develop dyslipidemia than A allele carriers (OR = 1.264, OR 95% CI: 1.037-1.541; P = 0.020).
|
29758034 |
2018 |
rs670
|
|
|
0.030 |
GeneticVariation |
BEFREE |
ApoB rs512535 and ApoA1 rs670 major G allele homozygotes had increased MetS risk (OR 1.65 [CI 1.24, 2.20], P = 0.0006; OR 1.42 [CI 1.08, 1.87], P = 0.013), which may be, partly, explained by their increased abdominal obesity and impaired insulin sensitivity (P<0.05) but not dyslipidemia.
|
21122859 |
2011 |
rs670
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The frequencies of the A allele for rs670 were found to be 14.3% (dyslipidemia group) and 12.7% (control group).
|
27173266 |
2016 |
rs671
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Furthermore, the ALDH2 Glu504Lys polymorphism has been shown to be associated with certain traditional cardiovascular risk factors, such as dyslipidemia, hypertension, and diabetes mellitus or hyperglycemia.
|
25263942 |
2014 |