|
rs324420
|
|
|
0.040 |
GeneticVariation |
BEFREE |
In this study we investigated inter-individual differences in mood response to amphetamine in relation to four polymorphisms in the FAAH gene, including the FAAH missense variant rs324420C --> A (Pro129Thr), which was previously found to be associated with street drug use and addictive traits.
|
19890266 |
2010 |
|
rs324420
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The fatty acid amide hydrolase C385A (P129T) missense variant in cannabis users: studies of drug use and dependence in Caucasians.
|
17290447 |
2007 |
|
rs324420
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The human fatty acid amide hydrolase (FAAH) missense mutation c.385 C-->A, which results in conversion of a conserved proline residue to threonine (P129T), has been associated with street drug use and problem drug abuse.
|
16972078 |
2006 |
|
rs324420
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Reduced cellular expression and activity of the P129T mutant of human fatty acid amide hydrolase: evidence for a link between defects in the endocannabinoid system and problem drug use.
|
15254019 |
2004 |
|
rs4680
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Early-Life Adversity and Blunted Stress Reactivity as Predictors of Alcohol and Drug use in Persons With COMT (rs4680) Val158Met Genotypes.
|
31150143 |
2019 |
|
rs29221
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The drug use years and rs29221 GG genotype were associated with relapse during the following 2 years after drug rehabilitation.
|
30143926 |
2018 |
|
rs6902403
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Conclusion:</b> Dosage of methadone, plasma methadone concentration, several SNPs (rs3192723, rs6912029, rs6902403) of the <i>OPRM1</i> gene, and age of first drug use were associated with better MMT outcomes.
|
30420869 |
2018 |
|
rs9825563
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, DRD3 rs9825563 may influence onset age of drug use, partially mediated by novelty seeking in the non-psychosis AD group.
|
28028606 |
2018 |
|
rs2108622
|
|
|
0.010 |
GeneticVariation |
BEFREE |
VKORC1 - 1639G > A, CYP2C9*3, and CYP4F2 rs2108622 polymorphisms together with age, body mass index, antiplatelet drug use, amiodarone use, and current smoker status explained 51.3% of individual variability in stable warfarin doses.
|
28550460 |
2017 |
|
rs6265
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We conducted a case-control study by assessing 194 methamphetamine-dependent patients and 378 healthy volunteers without history of drug use on the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) and the presence of the BDNF Val66Met polymorphism and serum BDNF levels.
|
26280836 |
2015 |
|
rs759834365
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We conducted a case-control study by assessing 194 methamphetamine-dependent patients and 378 healthy volunteers without history of drug use on the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) and the presence of the BDNF Val66Met polymorphism and serum BDNF levels.
|
26280836 |
2015 |
|
rs4704846
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We genotyped rs4704846 in three independent cohorts of HIV-1 exposed seronegative (HESN) individuals with different geographic origin (Italy and Spain) and distinct route of exposure to HIV-1 (sexual and injection drug use).
|
25180498 |
2014 |
|
rs1143627
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The polymorphisms IL10 C-592A (rs1800872), C-rs3024505-T, IL1b C-3737T (rs4848306), G-1464C (rs1143623), T-31C (rs1143627) and PTGS2 (encoding COX-2) A-1195G (rs689466), G-765C (rs20417), and T8473C (rs5275) were assessed in relation to risk of colorectal cancer (CRC) and interaction with diet (red meat, fish, fibre, cereals, fruit and vegetables) and lifestyle (non-steroid-anti-inflammatory drug use and smoking status) was assessed in a nested case-cohort study of nine hundred and seventy CRC cases and 1789 randomly selected participants from a prospective study of 57,053 persons.
|
24194923 |
2013 |
|
rs3024505
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The polymorphisms IL10 C-592A (rs1800872), C-rs3024505-T, IL1b C-3737T (rs4848306), G-1464C (rs1143623), T-31C (rs1143627) and PTGS2 (encoding COX-2) A-1195G (rs689466), G-765C (rs20417), and T8473C (rs5275) were assessed in relation to risk of colorectal cancer (CRC) and interaction with diet (red meat, fish, fibre, cereals, fruit and vegetables) and lifestyle (non-steroid-anti-inflammatory drug use and smoking status) was assessed in a nested case-cohort study of nine hundred and seventy CRC cases and 1789 randomly selected participants from a prospective study of 57,053 persons.
|
24194923 |
2013 |
|
rs4684677
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A significant association between the GHRL SNP rs4684677 and ASI composite score of drug use was also reported (pc = 0.03).
|
23579732 |
2013 |
|
rs4848306
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The polymorphisms IL10 C-592A (rs1800872), C-rs3024505-T, IL1b C-3737T (rs4848306), G-1464C (rs1143623), T-31C (rs1143627) and PTGS2 (encoding COX-2) A-1195G (rs689466), G-765C (rs20417), and T8473C (rs5275) were assessed in relation to risk of colorectal cancer (CRC) and interaction with diet (red meat, fish, fibre, cereals, fruit and vegetables) and lifestyle (non-steroid-anti-inflammatory drug use and smoking status) was assessed in a nested case-cohort study of nine hundred and seventy CRC cases and 1789 randomly selected participants from a prospective study of 57,053 persons.
|
24194923 |
2013 |
|
rs5275
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The polymorphisms IL10 C-592A (rs1800872), C-rs3024505-T, IL1b C-3737T (rs4848306), G-1464C (rs1143623), T-31C (rs1143627) and PTGS2 (encoding COX-2) A-1195G (rs689466), G-765C (rs20417), and T8473C (rs5275) were assessed in relation to risk of colorectal cancer (CRC) and interaction with diet (red meat, fish, fibre, cereals, fruit and vegetables) and lifestyle (non-steroid-anti-inflammatory drug use and smoking status) was assessed in a nested case-cohort study of nine hundred and seventy CRC cases and 1789 randomly selected participants from a prospective study of 57,053 persons.
|
24194923 |
2013 |
|
rs1799972
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A C17T polymorphism in the mu opiate receptor is associated with quantitative measures of drug use in African American women.
|
21070507 |
2012 |
|
rs3775291
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We genotyped rs3775291 in a population of Spanish HIV-1-exposed seronegative (HESN) individuals who remain HIV seronegative despite repeated exposure through i.v. injection drug use (IDU-HESN individuals) as witnessed by their hepatitis C virus seropositivity.
|
22174453 |
2012 |
|
rs737866
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the multivariate analysis the inclusion of the NS subscore variable weakened the relationship between the COMT rs737866 TT genotype and an earlier age of onset of drug use.
|
21857968 |
2011 |
|
rs4939827
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The odds ratios between SMAD7 and colon cancer among individuals reporting recent aspirin/nonsteroidal anti-inflammatory drug use was 0.60 (95% CI, 0.43-0.85) for the CC genotype of the rs4939827 polymorphism and 1.69 (95% CI, 1.20-2.38) for the TT genotype of the rs1295371 polymorphism.
|
20124488 |
2010 |
|
rs1042522
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We assessed the association of TP53 Arg72Pro and p53PIN3 polymorphisms with colorectal cancer risk and their possible interaction with nonsteroidal anti-inflammatory drug use.
|
17622940 |
2007 |
|
rs1131691014
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We assessed the association of TP53 Arg72Pro and p53PIN3 polymorphisms with colorectal cancer risk and their possible interaction with nonsteroidal anti-inflammatory drug use.
|
17622940 |
2007 |
|
rs878854066
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We assessed the association of TP53 Arg72Pro and p53PIN3 polymorphisms with colorectal cancer risk and their possible interaction with nonsteroidal anti-inflammatory drug use.
|
17622940 |
2007 |