|
rs1010824
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We analysed single nucleotide polymorphisms of ANGPT1 (rs2507800, rs1954727 and rs1010824), ANGPT2 (rs3739390, rs2442598 and rs1868554) and caspase-5 (rs507879, rs518604 and rs523104) in 343 patients with PV and 347 healthy controls (HCs) by the SNaPshot method, and evaluated the risk for psoriasis conferred by the individual polymorphisms and haplotypes.
|
25753570 |
2015 |
|
rs1020760
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To investigate the potential association between rs1020760 and phenotypes of psoriasis vulgaris, we performed a genotype-phenotype analysis.
|
27346731 |
2016 |
|
rs1056198
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture.
|
26626624 |
2015 |
|
rs10733113
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We genotyped eight SNPs, four from <i>NLRP1</i> (rs8079034, rs11651270, rs11657747, and rs878329) and <i>NLRP3</i> (rs7512998, rs3806265, rs10754557, and rs10733113) each in 540 patients with PsV and 612 healthy controls in the Chinese Han population using an improved multiplexed ligation detection reaction (iMLDR) method.
|
29850521 |
2018 |
|
rs10754557
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The haplotype analysis of rs3806265 and rs10754557 also presented a significant association of TA haplotype with PsV (<i>χ</i><sup>2</sup> = 4.529; <i>p</i> = 0.033).
|
29850521 |
2018 |
|
rs10759932
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The comparison of allele distributions revealed that only one SNP (rs3804099) of 6 common SNPs(rs10759932, rs11536889, rs11536891, rs1927914, rs3804099, rs4696480) was significant associated with the risk of PsV (P<0.01; FDR p-Value).
|
27155792 |
2016 |
|
rs10865331
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture.
|
26626624 |
2015 |
|
rs11652075
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CARD14 gene polymorphism c.C2458T (p.Arg820Trp) is associated with clinical features of psoriasis vulgaris in a Chinese cohort.
|
26249641 |
2016 |
|
rs1217691063
|
|
|
0.010 |
GeneticVariation |
BEFREE |
There was no significant increase of the MTHFR 677 C > T mutation in patients with psoriasis vulgaris compared with controls (χ(2) = 0.733, p = 0.392).
|
22217364 |
2012 |
|
rs12445568
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture.
|
26626624 |
2015 |
|
rs12489120
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture.
|
26626624 |
2015 |
|
rs1250544
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture.
|
26626624 |
2015 |
|
rs12884468
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture.
|
26626624 |
2015 |
|
rs1295685
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture.
|
26626624 |
2015 |
|
rs17716942
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture.
|
26626624 |
2015 |
|
rs17728338
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In PsV a significant association was found for IL28RA (rs4649203, P = 9.53 × 10(-7)), TNIP1 (rs17728338, P = 1.21 × 10(-4)) and ERAP1 (rs27524, P = 1.17 × 10(-3)).
|
23252691 |
2013 |
|
rs1799864
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the meanwhile, CCR5 rs1800024 polymorphism also exhibited significant differences in genotype and allele distribution (P < .05), demonstrating its promoting effect on the risk of PV under heterozygous model (OR = 1.73, 95% CI = 1.06-2.82), dominance model (OR = 1.83, 95% CI = 1.14-2.94), and allele model (OR = 1.68, 95% CI = 1.13-2.48).CCR2 rs1799864 and CCR5 rs1800024 polymorphisms may function as independent risk factors for PV in Chinese population.
|
29145242 |
2017 |
|
rs1800024
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the meanwhile, CCR5 rs1800024 polymorphism also exhibited significant differences in genotype and allele distribution (P < .05), demonstrating its promoting effect on the risk of PV under heterozygous model (OR = 1.73, 95% CI = 1.06-2.82), dominance model (OR = 1.83, 95% CI = 1.14-2.94), and allele model (OR = 1.68, 95% CI = 1.13-2.48).CCR2 rs1799864 and CCR5 rs1800024 polymorphisms may function as independent risk factors for PV in Chinese population.
|
29145242 |
2017 |
|
rs1800925
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Both SNPs were found to be highly associated with susceptibility to PsA (rs1800925 ptrend = 6.1 × 10(-5) OR 1.33, rs20541 ptrend = 8.0 × 10(-4) OR 1.27), but neither SNP was significantly associated with susceptibility to PsV.
|
21349879 |
2011 |
|
rs181359
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture.
|
26626624 |
2015 |
|
rs1868554
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We analysed single nucleotide polymorphisms of ANGPT1 (rs2507800, rs1954727 and rs1010824), ANGPT2 (rs3739390, rs2442598 and rs1868554) and caspase-5 (rs507879, rs518604 and rs523104) in 343 patients with PV and 347 healthy controls (HCs) by the SNaPshot method, and evaluated the risk for psoriasis conferred by the individual polymorphisms and haplotypes.
|
25753570 |
2015 |
|
rs201285077
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No cases of GPP harboured an interleukin-36RN mutation, but one of 16 cases of GPP with a family history of psoriasis vulgaris harboured a c.1805C>T (p.Ser602Leu) mutation in CARD14.
|
26358359 |
2016 |
|
rs20541
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Both SNPs were found to be highly associated with susceptibility to PsA (rs1800925 ptrend = 6.1 × 10(-5) OR 1.33, rs20541 ptrend = 8.0 × 10(-4) OR 1.27), but neither SNP was significantly associated with susceptibility to PsV.
|
21349879 |
2011 |
|
rs2066819
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture.
|
26626624 |
2015 |
|
rs2233278
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Variants at HLA-A, HLA-C, and HLA-DQB1 Confer Risk of Psoriasis Vulgaris in Japanese.
|
29031612 |
2018 |