|
rs2132397
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this study, three GJA8-tagged single nucleotide polymorphisms related to an increased ARC risk were identified: rs2132397 for general ARC under both dominant and additive models; rs7541950 for general ARC under both recessive and additive models; and rs6657114 for cortical cataract under the recessive model.
|
30349978 |
2018 |
|
rs6657114
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this study, three GJA8-tagged single nucleotide polymorphisms related to an increased ARC risk were identified: rs2132397 for general ARC under both dominant and additive models; rs7541950 for general ARC under both recessive and additive models; and rs6657114 for cortical cataract under the recessive model.
|
30349978 |
2018 |
|
rs7541950
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this study, three GJA8-tagged single nucleotide polymorphisms related to an increased ARC risk were identified: rs2132397 for general ARC under both dominant and additive models; rs7541950 for general ARC under both recessive and additive models; and rs6657114 for cortical cataract under the recessive model.
|
30349978 |
2018 |
|
rs9640883
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The identified interaction between rs9640883 and FBG in relation to cortical cataract was not replicated but may warrant further investigation.
|
30267098 |
2018 |
|
rs104893736
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we report the structure and α-crystallin binding interface of the G18V variant of human γS-crystallin (γS-G18V), which is linked to hereditary childhood-onset cortical cataract.
|
24183572 |
2013 |
|
rs1063147
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results show that WRN-rs11574311 was initially associated with ARC in general, cortical, and mixed cataracts (P = 0.003, odds ratio [OR] = 1.49; P = 0.001, OR = 1.68; and P < 0.0001, OR = 2.08), BLM-rs1063147 with nuclear cataract (P = 0.03, OR = 1.31), WRN-rs2725383 with cortical cataract (P = 0.01, OR = 1.49), and WRN-rs4733220 and WRN-rs2725338 with mixed cataract (P = 0.04, OR = 0.74; P = 0.003, OR = 0.60).
|
23322570 |
2013 |
|
rs11574311
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results show that WRN-rs11574311 was initially associated with ARC in general, cortical, and mixed cataracts (P = 0.003, odds ratio [OR] = 1.49; P = 0.001, OR = 1.68; and P < 0.0001, OR = 2.08), BLM-rs1063147 with nuclear cataract (P = 0.03, OR = 1.31), WRN-rs2725383 with cortical cataract (P = 0.01, OR = 1.49), and WRN-rs4733220 and WRN-rs2725338 with mixed cataract (P = 0.04, OR = 0.74; P = 0.003, OR = 0.60).
|
23322570 |
2013 |
|
rs2725338
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results show that WRN-rs11574311 was initially associated with ARC in general, cortical, and mixed cataracts (P = 0.003, odds ratio [OR] = 1.49; P = 0.001, OR = 1.68; and P < 0.0001, OR = 2.08), BLM-rs1063147 with nuclear cataract (P = 0.03, OR = 1.31), WRN-rs2725383 with cortical cataract (P = 0.01, OR = 1.49), and WRN-rs4733220 and WRN-rs2725338 with mixed cataract (P = 0.04, OR = 0.74; P = 0.003, OR = 0.60).
|
23322570 |
2013 |
|
rs2725383
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results show that WRN-rs11574311 was initially associated with ARC in general, cortical, and mixed cataracts (P = 0.003, odds ratio [OR] = 1.49; P = 0.001, OR = 1.68; and P < 0.0001, OR = 2.08), BLM-rs1063147 with nuclear cataract (P = 0.03, OR = 1.31), WRN-rs2725383 with cortical cataract (P = 0.01, OR = 1.49), and WRN-rs4733220 and WRN-rs2725338 with mixed cataract (P = 0.04, OR = 0.74; P = 0.003, OR = 0.60).
|
23322570 |
2013 |
|
rs4733220
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results show that WRN-rs11574311 was initially associated with ARC in general, cortical, and mixed cataracts (P = 0.003, odds ratio [OR] = 1.49; P = 0.001, OR = 1.68; and P < 0.0001, OR = 2.08), BLM-rs1063147 with nuclear cataract (P = 0.03, OR = 1.31), WRN-rs2725383 with cortical cataract (P = 0.01, OR = 1.49), and WRN-rs4733220 and WRN-rs2725338 with mixed cataract (P = 0.04, OR = 0.74; P = 0.003, OR = 0.60).
|
23322570 |
2013 |
|
rs13155993
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A genome-wide association study using 187,657 single nucleotide polymorphisms (SNPs) for the bivariate outcome of CC and THV identified genome-wide significant association with CTNND2 SNPs rs17183619, rs13155993 and rs13170756 (P<2.6 × 10(-7)).
|
22984439 |
2012 |
|
rs13170756
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A genome-wide association study using 187,657 single nucleotide polymorphisms (SNPs) for the bivariate outcome of CC and THV identified genome-wide significant association with CTNND2 SNPs rs17183619, rs13155993 and rs13170756 (P<2.6 × 10(-7)).
|
22984439 |
2012 |
|
rs17183619
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Statistical interaction was demonstrated between rs17183619 and APP SNP rs2096488 on CC (P = 0.0015) and CC-THV (P = 0.038).
|
22984439 |
2012 |
|
rs2096488
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Statistical interaction was demonstrated between rs17183619 and APP SNP rs2096488 on CC (P = 0.0015) and CC-THV (P = 0.038).
|
22984439 |
2012 |
|
rs6678616
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Common variants in EPHA2 were found that showed significant association with cortical cataract, and rs6678616 was the most significant in meta-analyses.
|
19649315 |
2009 |