Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs773256562
rs773256562
MAP3K9
0.700 GeneticVariation UNIPROT

dbSNP: rs779372373
rs779372373
ITK
0.700 GeneticVariation UNIPROT

dbSNP: rs781375003
rs781375003
BRDT
0.700 GeneticVariation UNIPROT

dbSNP: rs782203759
rs782203759
TRRAP
0.700 GeneticVariation UNIPROT

dbSNP: rs922655349
rs922655349
EPHA2
0.700 GeneticVariation UNIPROT

dbSNP: rs1217691063
rs1217691063
MTHFR
0.010 GeneticVariation BEFREE Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and susceptibility to gastric adenocarcinoma in an Italian population. 17972183

2007
dbSNP: rs397507444
rs397507444
MTHFR
0.010 GeneticVariation BEFREE Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and susceptibility to gastric adenocarcinoma in an Italian population. 17972183

2007
dbSNP: rs28933369
rs28933369
ERBB2 ; MIR4728
A 0.700 GeneticVariation CLINVAR Prediction of cancer driver mutations in protein kinases. 18339846

2008
dbSNP: rs1801282
rs1801282
PPARG
0.010 GeneticVariation BEFREE Analysis of Pro12Ala PPAR gamma polymorphism and Helicobacter pylori infection in gastric adenocarcinoma and peptic ulcer disease. 18372284

2008
dbSNP: rs1805192
rs1805192
PPARG
0.010 GeneticVariation BEFREE Analysis of Pro12Ala PPAR gamma polymorphism and Helicobacter pylori infection in gastric adenocarcinoma and peptic ulcer disease. 18372284

2008
dbSNP: rs1057519991
rs1057519991
TP53
0.710 GeneticVariation BEFREE Mutational analysis of the TP53 gene revealed a point mutation in exon 5 (A536G), which resulted in H179R in the gastric choriocarcinoma but not in the gastric adenocarcinoma. 19665071

2009
dbSNP: rs391957
rs391957
HSPA5 ; LOC107987127
0.010 GeneticVariation BEFREE These data provide the first evidence that the GRP78 rs391957 polymorphism can predict clinical outcome in localized GA and locally advanced CRC patients. 21382870

2011
dbSNP: rs2274223
rs2274223
PLCE1
0.010 GeneticVariation BEFREE Recent genome-wide association studies (GWAS) have found a single nucleotide polymorphism (SNP, rs2274223 A>G) in PLCE1 to be associated with risk of gastric adenocarcinoma. 22412849

2012
dbSNP: rs714
rs714
DCC
0.010 GeneticVariation BEFREE Further, DCC rs714 (A>G) AA genotype showed significantly increased risk for both gastric squamous cell carcinoma (OR = 5.63; P = 0.02; FDR Pcorr = 0.01) and gastric adenocarcinoma (OR = 2.15; P = 0.02; FDR Pcorr = 0.01). 23765761

2013
dbSNP: rs4986790
rs4986790
TLR4
0.010 GeneticVariation BEFREE We found the Asp299Gly polymorphism carrier to be significantly associated (p value 0.03)with the development of tumours in the distal part of the stomach and Thr399Ile polymorphism to be significantly associated(p value 0.008) with the development of well-differentiated gastric adenocarcinoma.The IL-8 T-251A polymorphism was not found to be associated with any of the clinicopathological characteristics. 24295404

2014
dbSNP: rs4986791
rs4986791
TLR4
0.010 GeneticVariation BEFREE We found the Asp299Gly polymorphism carrier to be significantly associated (p value 0.03)with the development of tumours in the distal part of the stomach and Thr399Ile polymorphism to be significantly associated(p value 0.008) with the development of well-differentiated gastric adenocarcinoma.The IL-8 T-251A polymorphism was not found to be associated with any of the clinicopathological characteristics. 24295404

2014
dbSNP: rs2296616
rs2296616
PANK1 ; MIR107
0.010 GeneticVariation BEFREE miR-107 is dysregulated in GAC pathogenesis and the SNP rs2296616 may play a role in the process. 25771723

2014
dbSNP: rs2294008
rs2294008
PSCA ; JRK
0.710 GeneticVariation BEFREE Two SNPs of rs2294008 (C>T) and rs2976392 (G>A) were identified to be associated with GAC risk. rs2294008, rs2976392 and rs10216533 made up two statistically significant haplotypes (Hap-CGG and Hap-TAG). 26006239

2015
dbSNP: rs10216533
rs10216533
PSCA
0.010 GeneticVariation BEFREE Two SNPs of rs2294008 (C>T) and rs2976392 (G>A) were identified to be associated with GAC risk. rs2294008, rs2976392 and rs10216533 made up two statistically significant haplotypes (Hap-CGG and Hap-TAG). 26006239

2015
dbSNP: rs2976392
rs2976392
PSCA ; JRK
0.010 GeneticVariation BEFREE Two SNPs of rs2294008 (C>T) and rs2976392 (G>A) were identified to be associated with GAC risk. rs2294008, rs2976392 and rs10216533 made up two statistically significant haplotypes (Hap-CGG and Hap-TAG). 26006239

2015
dbSNP: rs2294008
rs2294008
PSCA ; JRK
T 0.710 GeneticVariation GWASCAT Loss-of-function variants in ATM confer risk of gastric cancer. 26098866

2015
dbSNP: rs140081212
rs140081212
GBAP1
G 0.700 GeneticVariation GWASCAT Loss-of-function variants in ATM confer risk of gastric cancer. 26098866

2015
dbSNP: rs12826786
rs12826786 		0.010 GeneticVariation BEFREE A common functional single-nucleotide polymorphism (SNP) (rs12826786 C>T) at the HOTAIR promoter has been reported to influence HOTAIR expression and gastric adenocarcinoma susceptibility, but relation of HOTAIR rs12826786 C>T polymorphism with BC susceptibility and clinicopathological characteristics has yet to be reported. 26577852

2016
dbSNP: rs1057519991
rs1057519991
TP53
G 0.710 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs1023835002
rs1023835002
B2M ; PATL2
G 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016