Gene: PRSS1 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1223231582
rs1223231582
PRSS1
0.020 GeneticVariation BEFREE To our knowledge, this is the first reported case of chronic pancreatitis accompanied by pancreatic cancer in a patient with the SPINK1 N34S mutation. 15084977

2004
dbSNP: rs1223231582
rs1223231582
PRSS1
0.020 GeneticVariation BEFREE The frequencies of the promotor polymorphisms of IL10-627A, IL10-1117A, TNF-238A and TNF-308A in patients with alcoholic chronic pancreatitis, idiopathic pancreatitis, SPINK1-N34S-associated chronic pancreatitis and pancreatic cancer did not differ significantly from the control group. 14560157

2003
dbSNP: rs111033565
rs111033565
PRSS1
0.010 GeneticVariation BEFREE HP patients with the p.R122H mutation have a 35% lifetime risk of developing pancreatic cancer, but the oncogenetic process remains unknown. 18946221

2008
dbSNP: rs267606982
rs267606982
PRSS1
0.010 GeneticVariation BEFREE HP patients with the p.R122H mutation have a 35% lifetime risk of developing pancreatic cancer, but the oncogenetic process remains unknown. 18946221

2008
dbSNP: rs199769221
rs199769221
PRSS1
0.010 GeneticVariation BEFREE A relevant contribution of the Arg117His-mutation to pathogenesis of pancreatic cancer might be possible, since also asymptomatic individuals have been reported to carry this mutation and individuals with only mild symptoms may be undiagnosed as hp. 11062709

2000