Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs6265
rs6265
BDNF ; BDNF-AS
0.020 GeneticVariation BEFREE Gene-environment interaction effects were detected between the BDNF-Val66Met polymorphism and maternal care on phobic anxiety, paternal care on hostility, maternal overprotection on somatization and paternal overprotection also in somatization. 24768157

2014
dbSNP: rs759834365
rs759834365
BDNF ; BDNF-AS
0.020 GeneticVariation BEFREE Gene-environment interaction effects were detected between the BDNF-Val66Met polymorphism and maternal care on phobic anxiety, paternal care on hostility, maternal overprotection on somatization and paternal overprotection also in somatization. 24768157

2014
dbSNP: rs6265
rs6265
BDNF ; BDNF-AS
0.020 GeneticVariation BEFREE The present study investigated the association between whole region polymorphisms, (including the Val66Met variant), in the BDNF gene and phobic disorders among Han Chinese young adults. 21295349

2011
dbSNP: rs759834365
rs759834365
BDNF ; BDNF-AS
0.020 GeneticVariation BEFREE The present study investigated the association between whole region polymorphisms, (including the Val66Met variant), in the BDNF gene and phobic disorders among Han Chinese young adults. 21295349

2011
dbSNP: rs1256049
rs1256049
ESR2
0.010 GeneticVariation BEFREE The A allele of ESR2 rs1256049 was associated with an increased risk of GAD [OR: 2.06, 95% CI: 1.09-3.87], while both ESR1 polymorphisms were specifically associated with phobia. 21570196

2011
dbSNP: rs2234693
rs2234693
ESR1
0.010 GeneticVariation BEFREE The C allele of ESR1 rs2234693 decreased the risk of phobia by 42% [95% CI: 0.41-0.83], and this remained significant even after Bonferroni correction. 21570196

2011
dbSNP: rs9340799
rs9340799
ESR1
0.010 GeneticVariation BEFREE The G allele of ESR1 rs9340799 was associated with a 31% decreased phobia risk [95% CI: 0.49-0.96]. 21570196

2011
dbSNP: rs5751876
rs5751876
ADORA2A ; ADORA2A-AS1 ; SPECC1L-ADORA2A
0.010 GeneticVariation BEFREE A variant within the corresponding ADORA2A gene (rs5751876) increased the risk for panic disorder (PD), for elevated anxiety during challenge tests in healthy probands and for anxiety-related arousal in blood-injury phobia. 20334879

2010
dbSNP: rs4680
rs4680
COMT ; MIR4761
0.010 GeneticVariation BEFREE Functional polymorphisms in the MAO-A uVNTR promoter gene, the COMT gene (Val158Met) exon 4, and the 5-HTT promoter gene (44 bp ins/del) were investigated in 101 patients with phobic disorders of the anxiety spectrum and 202 controls matched to the patients for sex, age and ethnicity. 15450911

2004