Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1345176461
rs1345176461
IRF2BPL ; LOC107984638
A 0.700 GeneticVariation CLINVAR

dbSNP: rs1569324457
rs1569324457
ASXL1
C 0.700 CausalMutation CLINVAR

dbSNP: rs61751362
rs61751362
MECP2
A 0.700 GeneticVariation CLINVAR

dbSNP: rs730882246
rs730882246
NPC2 ; ISCA2
A 0.700 GeneticVariation CLINVAR

dbSNP: rs3782219
rs3782219
NOS1
0.010 GeneticVariation BEFREE The T allele of NOS1 SNP rs3782219 was negatively associated with spastic quadriplegia (OR = 0.742, 95% CI = 0.600-0.918, after SNPSpD correction, p = 0.023). 29940959

2018
dbSNP: rs1800796
rs1800796
IL6 ; STEAP1B ; IL6-AS1
0.010 GeneticVariation BEFREE However, subgroup analysis found significant differences in allele frequencies between spastic tetraplegia in males compared with controls at rs1800796 (OR=1.39, P=0.033, P=0.099 after SNPSpD correction) and rs2069837 (OR=1.58, P=0.012, P=0.035 after SNPSpD correction). 23415255

2013
dbSNP: rs2069837
rs2069837
IL6 ; IL6-AS1
0.010 GeneticVariation BEFREE However, subgroup analysis found significant differences in allele frequencies between spastic tetraplegia in males compared with controls at rs1800796 (OR=1.39, P=0.033, P=0.099 after SNPSpD correction) and rs2069837 (OR=1.58, P=0.012, P=0.035 after SNPSpD correction). 23415255

2013