Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs7590387
rs7590387
0.010 GeneticVariation BEFREE When genotype distribution for RAMP1 rs7590387 was compared between healthy controls (n = 209) and MOH patients, carriers of rs7590387GG were found at lower risk of developing MOH (OR: 0.43, 95%CI: 0.22-0.85, P = 0.011). 25881990

2015

dbSNP: rs4680
rs4680
0.010 GeneticVariation BEFREE Our results indicate that genotyping for COMT rs4680 and SLC6A4 STin2 VNTR could be useful for the identification of MOH patients at higher risk of poor prognosis after drug withdrawal. 24684248

2014

dbSNP: rs1217691063
rs1217691063
0.010 GeneticVariation BEFREE By multivariate logistic stepwise regression analysis, type of migraine, regular and sufficient dietary intake, and methylenetetrahydrofolate reductase (MTHFR) C677T (rs1801133) and dopamine D2 receptor (DRD2) C939T (rs6275) polymorphisms were selected as significant factors that contribute independently to the development from migraine to MOH (P < 0.05). 22290307

2013

dbSNP: rs1801133
rs1801133
0.010 GeneticVariation BEFREE By multivariate logistic stepwise regression analysis, type of migraine, regular and sufficient dietary intake, and methylenetetrahydrofolate reductase (MTHFR) C677T (rs1801133) and dopamine D2 receptor (DRD2) C939T (rs6275) polymorphisms were selected as significant factors that contribute independently to the development from migraine to MOH (P < 0.05). 22290307

2013

dbSNP: rs6275
rs6275
0.010 GeneticVariation BEFREE By multivariate logistic stepwise regression analysis, type of migraine, regular and sufficient dietary intake, and methylenetetrahydrofolate reductase (MTHFR) C677T (rs1801133) and dopamine D2 receptor (DRD2) C939T (rs6275) polymorphisms were selected as significant factors that contribute independently to the development from migraine to MOH (P < 0.05). 22290307

2013

dbSNP: rs1042173
rs1042173
0.010 GeneticVariation BEFREE Although a minor contribution of SLC6A4 variants in the genetic liability of MOH cannot be excluded, haplotype-based analysis of STin2 VNTR and rs1042173T>G polymorphisms allowed to identify a subgroup of MOH patients with a higher number of monthly headache and, possibly, with a more severe disease. 21585624

2012

dbSNP: rs6265
rs6265
0.010 GeneticVariation BEFREE Drug consumption in medication overuse headache is influenced by brain-derived neurotrophic factor Val66Met polymorphism. 19517061

2009

dbSNP: rs759834365
rs759834365
0.010 GeneticVariation BEFREE Drug consumption in medication overuse headache is influenced by brain-derived neurotrophic factor Val66Met polymorphism. 19517061

2009

dbSNP: rs734312
rs734312
0.010 GeneticVariation BEFREE To test the influence of WFS1 polymorphisms on medication overuse headache (MOH), a chronic headache condition related to symptomatic drugs overuse, we analyzed 82 MOH patients for the WFS1 His611Arg polymorphism, and performed a comparison between clinical features of Arg/Arg (R/R) and non-R/R individuals. 17719176

2007