|
rs4680
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Catechol-O-methyltransferase Val158-Met polymorphism and a response of hyperactive-impulsive symptoms to methylphenidate: A replication study from South Korea.
|
24763183 |
2014 |
|
rs4680
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The Barratt Impulsiveness Scale (BIS-11) was applied to 82 healthy volunteers (including 42 females) who were genotyped for COMT rs4680.
|
23440431 |
2013 |
|
rs4680
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Here we report an association study of both dopaminergic (COMT rs4680, DRD4 48 bp VNTR, DRD2/ANKK1 rs1800497) and serotonergic (HTR1A rs6925, HTR1B rs13212041, SLC6A4 5-HTTLPR) gene polymorphisms and trait impulsivity assessed with the Barratt Impulsiveness Scale (BIS-11) in a sample of 687 Caucasian young adults.
|
22259185 |
2012 |
|
rs4680
|
|
|
0.040 |
GeneticVariation |
BEFREE |
T/T carriers of HTR2A T102C polymorphism, that also had Met/Met genotype of COMT Val158Met single nucleotide polymorphism, scored significantly higher on impulsiveness than Val allele carriers (P=0.005).
|
20431430 |
2010 |
|
rs6313
|
|
|
0.030 |
GeneticVariation |
BEFREE |
In our main analyses with Barratt Impulsiveness Scale (BIS-11) total score, there were significant (i.e. p<.01 and False Discovery Rate <.10) interactions between (1) gender and TPH2 (rs1386483) genotype; (2) gender and HTR2A (rs6313) genotype; and epistatic interactions among (3) 5-HTTLPR and MAOA uVNTR; (4) 5-HTTLPR and rs6313 and (5) HTR1B (rs6296) and rs6313 genotypes.
|
22735397 |
2012 |
|
rs6313
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The interaction between COMT Val158Met and HTR2A T102C polymorphisms was found to be associated with subscale impulsiveness.
|
20431430 |
2010 |
|
rs6313
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Rates of commission (impulsive) errors in a variant of the Continuous Performance Test (CPT) were compared across the genotypes of the T102C polymorphism in adults recruited from the community.
|
11920859 |
2002 |
|
rs4245146
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Analysis revealed an influence of rs4245146 of the dopamine D2 receptor (DRD2) gene on the BIS-11 attention first-order factor, such that self-reported attentional impulsiveness increased in an additive fashion with each copy of the T allele.
|
28000543 |
2018 |
|
rs3219151
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No main effect of the GABRA6 rs3219151 was detected, but in those exposed to recent negative life events GABRA6 T allele increased current anxiety and depression as well as specific elements of suicide risk including suicidal and death-related thoughts, hopelessness, restlessness and agitation, insomnia and impulsiveness as measured by the STOP task.
|
29018204 |
2017 |
|
rs79874540
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Regression analyses showed that among the HTR2B Q20* carriers, temperamental traits resembled a passive-dependent personality profile, and the presence of the HTR2B Q20* predicted impulsive and aggressive behaviors particularly under the influence of alcohol.
|
26575222 |
2015 |
|
rs1130864
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We have previously reported an association between a polymorphism located in the CRP gene, +1444C>T (rs1130864), and the personality trait impulsiveness in women assessed using the Karolinska Scales of Personality.
|
23277135 |
2013 |
|
rs1360780
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The SNP rs1360780 showed a significant association; participants with more minor alleles (T) were less impulsive in intertemporal choice for delayed gain (multiplicity-corrected P = 0.047).
|
23857789 |
2013 |
|
rs279827
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A potential functional SNP rs279827, located next to a splice site, is located in the most significant region for both impulsiveness and LAPS.
|
23566244 |
2013 |
|
rs13212041
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here we report an association study of both dopaminergic (COMT rs4680, DRD4 48 bp VNTR, DRD2/ANKK1 rs1800497) and serotonergic (HTR1A rs6925, HTR1B rs13212041, SLC6A4 5-HTTLPR) gene polymorphisms and trait impulsivity assessed with the Barratt Impulsiveness Scale (BIS-11) in a sample of 687 Caucasian young adults.
|
22259185 |
2012 |
|
rs1386483
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In our main analyses with Barratt Impulsiveness Scale (BIS-11) total score, there were significant (i.e. p<.01 and False Discovery Rate <.10) interactions between (1) gender and TPH2 (rs1386483) genotype; (2) gender and HTR2A (rs6313) genotype; and epistatic interactions among (3) 5-HTTLPR and MAOA uVNTR; (4) 5-HTTLPR and rs6313 and (5) HTR1B (rs6296) and rs6313 genotypes.
|
22735397 |
2012 |
|
rs1800497
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here we report an association study of both dopaminergic (COMT rs4680, DRD4 48 bp VNTR, DRD2/ANKK1 rs1800497) and serotonergic (HTR1A rs6925, HTR1B rs13212041, SLC6A4 5-HTTLPR) gene polymorphisms and trait impulsivity assessed with the Barratt Impulsiveness Scale (BIS-11) in a sample of 687 Caucasian young adults.
|
22259185 |
2012 |
|
rs279826
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In a sample of 173 families (449 subjects), 129 of whom had at least one member diagnosed with alcohol dependence or abuse, carriers for the G allele in two single-nucleotide polymorphisms (SNPs) and haplotypes were more likely to have alcohol dependence symptoms (rs279858, P=0.01; rs279826, P=0.05; haplotype, P=0.02) and higher NEO Personality Inventory-Revised (NEO-PI-R) Impulsiveness scores (rs279858, P=0.016; rs279826, P=0.012; haplotype, P=0.032) with a stronger effect in women (rs279858, P=0.011; rs279826, P=0.002; haplotype, P=0.006), all P-values are corrected for family history and age.
|
21483437 |
2012 |
|
rs279858
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In a sample of 173 families (449 subjects), 129 of whom had at least one member diagnosed with alcohol dependence or abuse, carriers for the G allele in two single-nucleotide polymorphisms (SNPs) and haplotypes were more likely to have alcohol dependence symptoms (rs279858, P=0.01; rs279826, P=0.05; haplotype, P=0.02) and higher NEO Personality Inventory-Revised (NEO-PI-R) Impulsiveness scores (rs279858, P=0.016; rs279826, P=0.012; haplotype, P=0.032) with a stronger effect in women (rs279858, P=0.011; rs279826, P=0.002; haplotype, P=0.006), all P-values are corrected for family history and age.
|
21483437 |
2012 |
|
rs6296
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In our main analyses with Barratt Impulsiveness Scale (BIS-11) total score, there were significant (i.e. p<.01 and False Discovery Rate <.10) interactions between (1) gender and TPH2 (rs1386483) genotype; (2) gender and HTR2A (rs6313) genotype; and epistatic interactions among (3) 5-HTTLPR and MAOA uVNTR; (4) 5-HTTLPR and rs6313 and (5) HTR1B (rs6296) and rs6313 genotypes.
|
22735397 |
2012 |
|
rs6925
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here we report an association study of both dopaminergic (COMT rs4680, DRD4 48 bp VNTR, DRD2/ANKK1 rs1800497) and serotonergic (HTR1A rs6925, HTR1B rs13212041, SLC6A4 5-HTTLPR) gene polymorphisms and trait impulsivity assessed with the Barratt Impulsiveness Scale (BIS-11) in a sample of 687 Caucasian young adults.
|
22259185 |
2012 |
|
rs75634836
|
|
|
0.010 |
GeneticVariation |
BEFREE |
T/T carriers of HTR2A T102C polymorphism, that also had Met/Met genotype of COMT Val158Met single nucleotide polymorphism, scored significantly higher on impulsiveness than Val allele carriers (P=0.005).
|
20431430 |
2010 |
|
rs594242
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The complementary makers (rs594242-rs6311: G-C and rs6311: C) were associated with increased risk for non-violent (p=0.01; p=0.009 respectively) and impulsive suicidal behavior (p=0.03; p=0.01 respectively).
|
16814396 |
2006 |
|
rs6311
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The complementary makers (rs594242-rs6311: G-C and rs6311: C) were associated with increased risk for non-violent (p=0.01; p=0.009 respectively) and impulsive suicidal behavior (p=0.03; p=0.01 respectively).
|
16814396 |
2006 |
|
rs5569
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A significant association was found between norepinephrine transporter gene G1287A genotypes and response to methylphenidate for hyperactive-impulsive subscale scores (mean score reduction was 7.15 and 6.94 for G/G and G/A genotype, respectively, and 2.13 for A/A; p = .012) but not inattentive scores.
|
15322419 |
2004 |