|
rs1800896
|
|
|
0.030 |
GeneticVariation |
BEFREE |
In conclusion, <i>IL-10</i> gene rs1800896 polymorphism is associated with the decreased risk of PCa.
|
29029504 |
2017 |
|
rs1800896
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Minor alleles of rs2243250 (T) in IL4 (OR = 1.46, 95% CI 1.03-2.08, P-trend = 0.03), rs1800896 (G) in IL10 (OR = 0.77, 95% CI 0.61-0.96, P-trend = 0.02), rs2430561 (A) in IFNG (OR = 1.33, 95% CI 1.02-1.74; P-trend = 0.04), rs3747531 (C) in MSR1 (OR = 0.55, 95% CI 0.32-0.95; P-trend = 0.03), and possibly rs4073 (A) in IL8 (OR = 0.81, 95% CI 0.64-1.01, P-trend = 0.06) were associated with higher- (Gleason 7-10; N = 222), but not lower- (Gleason 2-6; N = 380) grade prostate cancer.
|
28317149 |
2017 |
|
rs1800896
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We found no association between IL-10 gene rs1800896 polymorphism and PCa in overall population (G versus A: OR=1.00, 95%CI=0.91-1.10, P=0.99; AG+GG versus AA: OR=1.18, 95%CI=0.97-1.43, P=0.10; GG versus AA+AG: OR=1.04, 95%CI=0.86-1.26, P=0.67).
|
21211963 |
2011 |
|
rs1800871
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We did not detect an association between IL-10 gene rs1800871 polymorphism and PCa in overall population (T versus C: OR=0.96, 95%CI=0.85-1.08, P=0.51; CT+TT versus CC: OR=0.94, 95%CI=0.80-1.11, P=0.48; TT versus CC+CT: OR=0.94, 95%CI=0.81-1.10, P=0.44).
|
21211963 |
2011 |
|
rs1800872
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This meta-analysis suggests that there is no association between IL-10 gene rs1800896, rs1800871 and rs1800872 polymorphisms and PCa.
|
21211963 |
2011 |
|
rs3024496
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Associations of IL10 haplotypes with prostate cancer were explained by high linkage disequilibrium between two tagSNPs (rs1800890 and rs3024496) and -1082G>A.
|
19267370 |
2009 |